Respiratory Infections in Children Associated to Parainfluenza Virus Type 4

Little is known about the role of certain viruses, such as parainfluenza virus type 4 (HPIV-4) in the etiology of respiratory infections. The objective of this study is to present preliminary data on respiratory infections associated with HPIV-4 in children living in the city of Fortaleza capital of the state of Ceará, Brazil. A set of 846 samples of nasopharyngeal aspirates collected during four years from children with acute respiratory infections were submitted to direct immunofluorescence for the detection of HPIV-4. Fifteen HPIV-4 were detected. Cases of the upper respiratory infections, bronchiolitis and pneumonia were associated to this virus. Further studies are needed to clarify the clinical significance of HPIV-4 infections

Protocolo de manejo de suspeita de infecção viral de vias respiratórias em pacientes com neoplasia hematológica do serviço de hematologia e transplante de medula óssea do Hospital Universitário Walter Cantídio (HUWC)

Infecção respiratória viral é causa significativa de morbi-mortalidade em paciente com doenças hematológicas. Deve ser suspeitado sempre que houver sintomas como coriza, obstrução nasal, odinofagia, tosse e dispnéia e deve-se seguir à identificação viral, quando possível. Os casos podem ser classificados como possível, provável ou confirmado. E observando-se o risco de progressão da infecção para vias aéreas inferiores, o diagnóstico deve ser precoce e as medidas terapêuticas específicas aos vírus bem como medidas de controle da infecção no ambiente hospitalar devem ser prontamente tomadas. O presente trabalho visa descrever um protocolo de manejo da infecção viral de vias respiratórias em pacientes com neoplasia hematológica dentro do Serviço de Hematologia e Transplante de medula do Hospital Universitário Walter Cantídio

Trajetórias da Educomunicação nas Políticas Públicas e a Formação de seus Profissionais

Esta obra é composta com os trabalhos apresentados no primeiro subtema, TRAJETÓRIA – Educação para a Comunicação como Política pública, nas perspectivas da Educomunicação e da Mídia-Educação, do II Congresso Internacional de Comunicação e Educação. Os artigos pretendem propiciar trocas de informações e produzir reflexões com os leitores sobre os caminhos percorridos, e ainda a percorrer, tendo como meta a expansão e a legitimação das práticas educomunicativas e/ou mídia-educativas como política pública para o atendimento à formação de crianças, adolescentes, jovens e adultos, no Brasil e no mundo

Infecções respiratórias agudas virais em crianças de Salvador: análise antigênica e genômica dos vírus sincicial respiratório e adenovírus isolados com correlação clínica

Submitted by Repositório Arca ([email protected]) on 2019-09-04T17:23:20Z No. of bitstreams: 1 license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2019-09-05T18:28:56Z (GMT) No. of bitstreams: 2 Fernada Edna Araujo Moura Interações...2001.pdf: 88974128 bytes, checksum: b834b47401291b6974bdf1212d5e4588 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5)Made available in DSpace on 2019-09-05T18:28:56Z (GMT). No. of bitstreams: 2 Fernada Edna Araujo Moura Interações...2001.pdf: 88974128 bytes, checksum: b834b47401291b6974bdf1212d5e4588 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2001À Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.O presente estudo foi desenvolvido com o objetivo de contribuir para o conhecimento da prevalência viral em casos de infecções respiratórias agudas (IRA) em crianças de Salvador, assim como realizar a caracterização antigênica e genômica dos adenovírus e vírus sincicial respiratório (VSR) isolados. Um total de 482 casos de infecção respiratória aguda do ano de 1998 foram investigados quanto a etiologia viral através de imunofluorescência indireta e isolamento em cultura celular. Trinta adenovírus isolados em 1998, 1997 e 1996 foram submetidos soroneutralização e análise de restrição enzimática. Imunofluorescência indireta e ELISA foram utilizados para caracterização antigênica de VSR detectados em 1998 e 1999, respectivamente. A caracterização genômica de VSR foi realizada através da amplificação do gene da proteína G e posterior seqüenciamento de nucleotídeos. Cento e cinquenta e quatro casos de infecção respiratória aguda tiveram sua etiologia viral diagnosticada. Os vírus mais prevalentes em ordem decrescente foram o VSR, influenza A, parainfluenza 3, adenovírus, influenza B e parainfluenza 1. As IRA virais acometeram principalmente crianças até um ano de idade, do sexo masculino, e foram diagnosticadas predominantemente como infecção de vias aéreas superiores. Dos 30 Adenovírus analisados, dezoito eram Ad2, seis Adl, cinco Ad3 e um Ad5. A caracterização genômica dos Ad2 mostrou que circularam o genotipo D5 e uma nova variante genômica. Entre os Ad 1, circularam o genotipo DI e duas novas variantes genômicas. Representantes dos Ad3 e Ad5 foram os tipos genômicos 3f e 5#, respectivamente. Entre 84 VSR detectados em 1998,64 pertenciam ao grupo A e 14 ao grupo B. A análise genômica de 6 cepas de VSR mostrou a existência de vários genótipos circulantes em 1999. O VSR foi o vírus mais prevalente entre sete vírus investigados. Durante o mesmo período epidêmico houve a circulação de ambos os grupos antigênicos e de vários genótipos de VSR. Genotipos do grupo B de Salvador não parecem estar relacionadas com as cepas B uruguaias. Houve um predomínio de Adenovírus do subgênero C, representados predominantemente pelos Ad2 e Adl. Alguns genotipos de adenovírus até então não detectados no Brasil circularam em Salvador durante o período de estudo.The present study was performed with the aim of to contribute for the knowledge of viral prevalence in acute respiratory infections (ARI) in children from Salvador, as to characterize in the antigenic and genomic level isolates of respiratory syncytial virus and adenovirus. Indirect immunofluorescence and cell culture isolation were used to investigate the viral etiology of 482 cases of acute respiratory infections observed during 1998.Thirty adenoviruses were isolated during 1998, 1997 and 1996 were submitted to soroneutralization and restriction enzyme analysis. Respiratory syncytial virus (RSV) detected in 1998 and 1999 were submitted to Indirect immunofluoresce and ELISA, respectively, for antigenic characterization. Partial nucleotide sequences of gene G of group A and B RSV strains were analised for genomic characterization. Viruses were detected in 154 cases of ARI. RSV, Influenza A, Parainfluenzavirus type 3, Adenovirus, Influenza B and Parainfluenzavirus type 1 were the most prevalent viruses in decreasing order. IRA were more frequent in children untill one year of age and male, and were diagnosed mostly as upper respiratory tract infections. From 30 analised adenoviruses for soroneutralization were detected 18 Ad2, 6 Adi, 5 Ad3 and 1 Ad5. Seventeen of eigtheen Ad2 were represented by genotype D5.A new variant genomic of Ad2 circulated in 1996.Among Adi were found the genotype Dl(lp) and two new genomic variants.The only genotypes of Ad3 e Ad5 were 3f and 5# , respectively. Among 84 RSV, 64 belonged to group A and 14 to group B. Fourteen antigenic variants ans several genotypes of RSV circulated during 1999. RSV was the most prevalent virus among the seven investigated and the main agent of lower respiratory tract infection. Both antigenic groups and several genotypes of RSV circulated during the same epidemic period. RSV B strains from Salvador were not correlated with strains isolated in Uruguay. Subgenus C of adenovirus was predominant and was represented mostly by Ad2 and Adi.Some genotypes of adenovirus still not detected in Brazil were found in Salvador

Parainfluenza virus infections in a tropical city: clinical and epidemiological aspects

Little information on the epidemiology and clinical characteristics of human parainfluenza virus (HPIV) infections, especially in children from tropical countries, has been published. The aim of this study was to determine the frequency of HPIV infections in children attended at a large hospital in Fortaleza in Northeast Brazil, and describe seasonal patterns, clinical and epidemiological characteristics of these infections. From January 2001 to December 2006, a total of 3070 nasopharyngeal aspirates collected from children were screened by indirect immunofluorescence for human parainfluenza viruses 1, 2, and 3 (HPIV-1, 2 and 3) and other respiratory viruses. Viral antigens were identified in 933 samples and HPIV in 117. The frequency of HPIV-3, HPIV-1 and HPIV-2 was of 83.76%, 11.96% and 4.27%, respectively. Only HPIV-3 showed a seasonal occurrence, with most cases observed from September to November, and with an inverse relationship to the rainy season. Most HPIV-3 infections seen in outpatients were diagnosed as upper respiratory tract infections

Respiratory syncytial virus infections during an epidemic period in Salvador, Brazil. Viral antigenic group analysis and description of clinical and epidemiological aspects.

Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2012-03-27T21:13:35Z No. of bitstreams: 1 Moura FE Respiratory syncytial virus....pdf: 541227 bytes, checksum: c94434b568a112eaaf6798cafe97ae38 (MD5)Made available in DSpace on 2012-03-27T21:13:35Z (GMT). No. of bitstreams: 1 Moura FE Respiratory syncytial virus....pdf: 541227 bytes, checksum: c94434b568a112eaaf6798cafe97ae38 (MD5) Previous issue date: 2003Universidade Federal do Ceará. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.Acute respiratory infections (ARI) caused by respiratory syncytial virus (RSV) were studied in 482 children from Salvador, BA, Brazil, over a period of 12 months. The epidemic period of RSV infections in Salvador occurred from February (summer) to August (winter), with peaks in May, June, and July. The grouping characteristics of 84 RSV present in nasopharyngeal secretions of children seen at a reference university hospital were analyzed. RSV represented 17.4% of all cases and 54.5% of the positive samples. Sixty-four RSV strains were assigned to group A and 14 to group B. Both groups circulated in the five months of the epidemic period studied. Infections by both groups of RSV were more frequent in children up to one year of age. The incidence of RSV ARI was slightly more frequent in males, although group B had more infected females

Respiratory Syncytial Virus Infections during an Epidemic Period in Salvador, Brazil. Viral Antigenic Group Analysis and Description of Clinical and Epidemiological Aspects

Acute respiratory infections (ARI) caused by respiratory syncytial virus (RSV) were studied in 482 children from Salvador, BA, Brazil, over a period of 12 months. The epidemic period of RSV infections in Salvador occurred from February (summer) to August (winter), with peaks in May, June, and July. The grouping characteristics of 84 RSV present in nasopharyngeal secretions of children seen at a reference university hospital were analyzed. RSV represented 17.4% of all cases and 54.5% of the positive samples. Sixty-four RSV strains were assigned to group A and 14 to group B. Both groups circulated in the five months of the epidemic period studied. Infections by both groups of RSV were more frequent in children up to one year of age. The incidence of RSV ARI was slightly more frequent in males, although group B had more infected females