On a model mechanism for the spatial patterning of teeth primordia in the Alligator

We propose a model mechanism for the initiation and spatial positioning of teeth primordia in the alligator,Alligator mississippiensis. Detailed embryological studies by Westergaard & Ferguson (1986, 1987, 1990) show that jaw growth plays a crucial role in the developmental patterning of the tooth initiation process. Based on biological data we develop a reaction-diffusion mechanism, which crucially includes domain growth. The model can reproduce the spatial pattern development of the first seven teeth primordia in the lower half jaw ofA. mississippiensis. The results for the precise spatio-temporal sequence compare well with detailed developmental experiments

Description of an ancient social bee trapped in amber using diagnostic radioentomology

The application of non-invasive imaging technologies using X-radiation (diagnostic radioentomology, ‘DR') is demonstrated for the study of amber-entombed social bees. Here, we examine the external and internal morphology of an Early Miocene (Burdigalian) stingless bee (Apinae: Meliponini) from the Dominican Republic using non-destructive X-ray microtomography analysis. The study permits the accurate reconstruction of features otherwise obscured or impossible to visualize without destroying the sample and allows diagnosis of the specimen as a new species, Proplebeia adbita Greco and Enge

Measurements of the Diffuse Ultraviolet Background and the Terrestrial Airglow with the Space Telescope Imaging Spectrograph

Far-UV observations in and near the Hubble Deep Fields demonstrate that the Space Telescope Imaging Spectrograph (STIS) can potentially obtain unique and precise measurements of the diffuse far-ultraviolet background. Although STIS is not the ideal instrument for such measurements, high-resolution images allow Galactic and extragalactic objects to be masked to very faint magnitudes, thus ensuring a measurement of the truly diffuse UV signal. The programs we have analyzed were not designed for this scientific purpose, but would be sufficient to obtain a very sensitive measurement if it were not for a weak but larger-than-expected signal from airglow in the STIS 1450-1900 A bandpass. Our analysis shows that STIS far-UV crystal quartz observations taken near the limb during orbital day can detect a faint airglow signal, most likely from NI\1493, that is comparable to the dark rate and inseparable from the far-UV background. Discarding all but the night data from these datasets gives a diffuse far-ultraviolet background measurement of 501 +/- 103 ph/cm2/sec/ster/A, along a line of sight with very low Galactic neutral hydrogen column (N_HI = 1.5E20 cm-2) and extinction (E(B-V)=0.01 mag). This result is in good agreement with earlier measurements of the far-UV background, and should not include any significant contribution from airglow. We present our findings as a warning to other groups who may use the STIS far-UV camera to observe faint extended targets, and to demonstrate how this measurement may be properly obtained with STIS.Comment: 7 pages, Latex. 4 figures. Uses corrected version of emulateapj.sty and apjfonts.sty (included). Accepted for publication in A

Rabies elimination research: juxtaposing optimism, pragmatism and realism

More than 100 years of research has now been conducted into the prevention, control and elimination of rabies with safe and highly efficacious vaccines developed for use in human and animal populations. Domestic dogs are a major reservoir for rabies, and although considerable advances have been made towards the elimination and control of canine rabies in many parts of the world, the disease continues to kill tens of thousands of people every year in Africa and Asia. Policy efforts are now being directed towards a global target of zero human deaths from dog-mediated rabies by 2030 and the global elimination of canine rabies. Here we demonstrate how research provides a cause for optimism as to the feasibility of these goals through strategies based around mass dog vaccination. We summarize some of the pragmatic insights generated from rabies epidemiology and dog ecology research that can improve the design of dog vaccination strategies in low- and middle-income countries and which should encourage implementation without further delay. We also highlight the need for realism in reaching the feasible, although technically more difficult and longer-term goal of global elimination of canine rabies. Finally, we discuss how research on rabies has broader relevance to the control and elimination of a suite of diseases of current concern to human and animal health, providing an exemplar of the value of a ‘One Health’ approach

The Large-scale and Small-scale Clustering of Lyman-Break Galaxies at 3.5 < z< 5.5 from the GOODS survey

We report on the angular correlation function of Lyman-break galaxies (LBGs) at z~4 and 5 from deep samples obtained from the Great Observatories Deep Origins Survey (GOODS). Similar to LBGs at z~3, the shape of w(theta) of the GOODS LBGs is well approximated by a power-law with slope beta~0.6 at angular separation theta > 10 arcsec. The clustering strength of z~4, 5 LBGs also depends on the rest-frame UV luminosity, with brighter galaxies more strongly clustered than fainter ones, implying a general correlation between halos' mass and LBGs' star-formation rate. At smaller separations, w(theta) of deep samples significantly exceeds the extrapolation of the large-scale power-law fit, implying enhanced spatial clustering at scales r < 1 Mpc. We also find that bright LBGs statistically have more faint companions on scales theta < 20 arcsec than fainter ones, showing that the enhanced small-scale clustering is very likely due to sub-structure, namely the fact that massive halos can host multiple galaxies. A simple model for the halo occupation distribution and the CDM halo mass function reproduce well the observed w(theta). The scaling relationship of the clustering strength with volume density and with redshift is quantitatively consistent with that of CDM halos. A comparison of the clustering strength of three samples of equal luminosity limit at z ~ 3, 4 and 5 shows that the LBGs at z~5 are hosted in halos about one order of magnitude less massive than those in the lower redshift bins, suggesting that star-formation was more efficient at higher-redshift.Comment: replaced with the version accepted for publication in ApJ. 46 pages, 10 figures; minor changes to text, one subsection adde

Spectroscopic Observations of Lyman-Break Galaxies at Redshift ~ 4, 5 and 6 in the GOODS-South Field

We report on observations of Lyman-break galaxies (LBGs) selected from the Great Observatories Origins Deep Survey at mean redshift z~4, 5 and 6, obtained with FORS2 spectrograph at the ESO-VLT.This program has yielded spectroscopic identifications for 114 galaxies of which 51 are at z~4, 31 at z~5, and 32 at z~6. The adopted selection criteria are effective, identifying galaxies at the expected redshift with minimal foreground contamination. Once selection effects are properly accounted for, the rest-frame UV spectra of the higher-redshift LBGs appear to be similar to their counterparts at z~3. As at z~3, LBGs at z~4 and z~5 show Lya both in emission and in absorption; when in absorption, strong interstellar lines and red UV spectra are observed, a fact also measured at z~2 and 3. At z~6, sensitivity issues bias our sample towards galaxies with Lya in emission; nevertheless, these spectra appear to be similar to their lower-redshift counterparts. As in other studies at similar redshifts, we find clear evidence that brighter LBGs tend to have weaker Lya emission lines. At fixed rest-frame UV luminosity, the equivalent width of the Lya emission line is larger at higher redshifts. At all redshifts where the measurements can be reliably made, the redshift of the Lya emission line turns out to be larger than that of the interstellar absorption lines,with a median velocity difference DeltaV~400 km/s at z~4 and 5, consistent with results at lower redshifts. This shows that powerful, large-scale winds are common at high redshift.In general,there is no strong correlation between the morphology of the UV light and the spectroscopic properties. However, galaxies with deep interstellar absorption lines and strong Lya absorption appear to be more diffuse than galaxies with Lya in emission.(abridged)Comment: 58 pages, 19 figures, accepted for publication in The Astrophysical Journa

Stellar populations across the NGC4244 truncated galactic disk

We use HST/ACS to study the resolved stellar populations of the nearby, nearly edge-on galaxy NGC4244 across its outer disk surface density break. The stellar photometry allows us to study the distribution of different stellar populations and reach very low equivalent surface brightnesses. We find that the break occurs at the same radius for young, intermediate age, and old stars. The stellar density beyond the break drops sharply by a factor of at least 600 in 5 kpc. The break occurs at the same radius independent of height above the disk, but is sharpest in the midplane and nearly disappears at large heights. These results make it unlikely that truncations are caused by a star formation threshold alone: the threshold would have to keep the same radial position from less than 100 Myr to 10 Gyr ago, in spite of potential disturbances such as infall and redistribution of gas by internal processes. A dynamical interpretation of truncation formation is more likely such as due to angular momentum redistribution by bars or density waves, or heating and stripping of stars caused by the bombardment of dark matter sub-halos. The latter explanation is also in quantitative agreement with the small diffuse component we see around the galaxy.Comment: ApJ Letters, in press. Five pages, 2 figure

Description of an ancient social bee trapped in amber using diagnostic radioentomology

The application of non-invasive imaging technologies using X-radiation (diagnostic radioentomology, ‘DR’) is demonstrated for the study of amber-entombed social bees. Here, we examine the external and internal morphology of an Early Miocene (Burdigalian) stingless bee (Apinae: Meliponini) from the Dominican Republic using non-destructive X-ray microtomography analysis. The study permits the accurate reconstruction of features otherwise obscured or impossible to visualize without destroying the sample and allows diagnosis of the specimen as a new species, Proplebeia adbita Greco and Engel