The Dust Content of Galaxy Clusters

We report on the detection of reddening toward z ~ 0.2 galaxy clusters. This is measured by correlating the Sloan Digital Sky Survey cluster and quasar catalogs and by comparing the photometric and spectroscopic properties of quasars behind the clusters to those in the field. We find mean E(B-V) values of a few times 10^-3 mag for sight lines passing ~Mpc from the clusters' center. The reddening curve is typical of dust but cannot be used to distinguish between different dust types. The radial dependence of the extinction is shallow near the cluster center suggesting that most of the detected dust lies at the outskirts of the clusters. Gravitational magnification of background z ~ 1.7 sources seen on Mpc (projected) scales around the clusters is found to be of order a few per cent, in qualitative agreement with theoretical predictions. Contamination by different spectral properties of the lensed quasar population is unlikely but cannot be excluded.Comment: 4 pages, 3 figure

The Luminosity Function of Galaxies in Compact Groups

From R-band images of 39 Hickson compact groups (HCGs), we use galaxy counts to determine a luminosity function extending to M_R=-14.0, approximately two magnitudes deeper than previous compact group luminosity functions. We find that a single Schechter function is a poor fit to the data, so we fit a composite function consisting of separate Schechter functions for the bright and faint galaxies. The bright end is best fit with M^*=-21.6 and alpha=-0.52 and the faint end with M^*=-16.1 and alpha=-1.17. The decreasing bright end slope implies a deficit of intermediate luminosity galaxies in our sample of HCGs and the faint end slope is slightly steeper than that reported for earlier HCG luminosity functions. Furthermore, luminosity functions of subsets of our sample reveal more substantial dwarf populations for groups with x-ray halos, groups with tidal dwarf candidates, and groups with a dominant elliptical or lenticular galaxy. Collectively, these results support the hypothesis that within compact groups, the initial dwarf galaxy population is replenished by "subsequent generations" formed in the tidal debris of giant galaxy interactions.Comment: 26 pages, to be published in The Astrophysical Journal, 8 greyscale plates (figures 1 and 2) can be retrieved at http://www.astro.psu.edu/users/sdh/pubs.htm

Investigating the timecourse of accessing conversational implicatures during incremental sentence interpretation

Many contextual inferences in utterance interpretation are explained as following from the nature of conversation and the assumption that participants are rational. Recent psycholinguistic research has focussed on certain of these ‘Gricean’ inferences and have revealed that comprehenders can access them in online interpretation. However there have been mixed results as to the time-course of access. Some results show that Gricean inferences can be accessed very rapidly, as rapidly as any other contextually specified information (Sedivy, 2003; Grodner, Klein, Carbery, & Tanenhaus, 2010); while other studies looking at the same kind of inference suggest that access to Gricean inferences are delayed relative to other aspects of semantic interpretation (Huang & Snedeker, 2009; in press). While previous timecourse research has focussed on Gricean inferences that support the online assignment of reference to definite expressions, the study reported here examines the timecourse of access to scalar implicatures, which enrich the meaning of an utterance beyond the semantic interpretation. Even if access to Gricean inference in support of reference assignment may be rapid, it is still unknown whether genuinely enriching scalar implicatures are delayed. Our results indicate that scalar implicatures are accessed as rapidly as other contextual inferences. The implications of our results are discussed in reference to the architecture of language comprehension

The Rest-Frame UV Luminosity Density of Star-Forming Galaxies at Redshifts z>3.5

We have measured the rest--frame lambda~1500 Ang comoving specific luminosity density of star--forming galaxies at redshift 3.5<z<6.5 from deep images taken with the Hubble Space Telescope (HST)and the Advanced Camera for Surveys (ACS), obtained as part of the Great Observatories Origins Deep Survey (GOODS). We used color selection criteria to construct samples of star--forming galaxies at redshifts z~4, 5 and 6, identified by the signature of the 912 Ang Lyman continuum discontinuity and Lyman-alpha forest blanketing in their rest--frame UV colors (Lyman--break galaxies). The ACS samples cover ~0.09 square degree, and are also relatively deep, reaching between 0.2 and 0.5 L_3^*, depending on the redshift, where $L_3^*$ is the characteristic UV luminosity of Lyman--break galaxies at z~3. The specific luminosity density of Lyman--break galaxies appears to be nearly constant with redshift from z~3 to z~6, although the measure at z~6 remains relatively uncertain, because it depends on the accurate estimate of the faint counts of the z~6 sample. If Lyman--break galaxies are fair tracers of the cosmic star formation activity, our results suggest that at z~6 the universe was already producing stars as vigorously as it did near its maximum several Gyr later, at 1<~z<~3. Thus, the onset of large--scale star formation in the universe is to be sought at around z~6 or higher, namely at less than ~7% of the current cosmic age.Comment: AAS LaTeX macros 4.0, 11 pages, 1 postscript figure. Accepted for publication in The Astrophysical Journal, Letter. Minor changes to the figure caption. The data and the GOODS-group papers can be found at http://www.stsci.edu/science/goods

Far-ultraviolet imaging of the Hubble Deep Field-North: Star formation in normal galaxies at z < 1

We present far-ultraviolet (FUV) imaging of the Hubble Deep Field-North (HDF-N) taken with the Solar Blind Channel of the Advanced Camera for Surveys (ACS SBC) and the FUV MAMA detector of the Space Telescope Imaging Spectrograph onboard the Hubble Space Telescope. The full WFPC2 deep field has been observed at 1600 Å. We detect 134 galaxies and one star down to a limit of FUV_(AB) ~ 29. All sources have counterparts in the WFPC2 image. Redshifts (spectroscopic or photometric) for the detected sources are in the range 0 < z < 1. We find that the FUV galaxy number counts are higher than those reported by GALEX, which we attribute at least in part to cosmic variance in the small HDF-N field of view. Six of the 13 Chandra sources at z < 0.85 in the HDF-N are detected in the FUV, and those are consistent with starbursts rather than active galactic nuclei. Cross-correlating with Spitzer sources in the field, we find that the FUV detections show general agreement with the expected L_(IR)/L_(UV) versus β relationship. We infer star formation rates (SFRs), corrected for extinction using the UV slope, and find a median value of 0.3 M_☉ yr^(-1) for FUV-detected galaxies, with 75% of detected sources having SFR < 1 M_☉ yr^(-1). Examining the morphological distribution of sources, we find that about half of all FUV-detected sources are identified as spiral galaxies. Half of morphologically selected spheroid galaxies at z < 0.85 are detected in the FUV, suggesting that such sources have had significant ongoing star formation in the epoch since z ~ 1

Dynamical Friction in dE Globular Cluster Systems

The dynamical friction timescale for globular clusters to sink to the center of a dwarf elliptical galaxy (dE) is significantly less than a Hubble time if the halos have King-model or isothermal profiles and the globular clusters formed with the same radial density profile as the underlying stellar population. We examine the summed radial distribution of the entire globular cluster systems and the bright globular cluster candidates in 51 Virgo and Fornax Cluster dEs for evidence of dynamical friction processes. We find that the summed distribution of the entire globular cluster population closely follows the exponential profile of the underlying stellar population. However, there is a deficit of bright clusters within the central regions of dEs (excluding the nuclei), perhaps due to the orbital decay of these massive clusters into the dE cores. We also predict the magnitude of each dE's nucleus assuming the nuclei form via dynamical friction. The observed trend of decreasing nuclear luminosity with decreasing dE luminosity is much stronger than predicted if the nuclei formed via simple dynamical friction processes. We find that the bright dE nuclei could have been formed from the merger of orbitally decayed massive clusters, but the faint nuclei are several magnitudes fainter than expected. These faint nuclei are found primarily in M_V > -14 dEs which have high globular cluster specific frequencies and extended globular cluster systems. In these galaxies, supernovae-driven winds, high central dark matter densities, extended dark matter halos, the formation of new star clusters, or tidal interactions may act to prevent dynamical friction from collapsing the entire globular cluster population into a single bright nucleus.Comment: 15 pages, 2 tables, 7 figures; to appear in the Astrophysical Journal, April 20, 200

Recovery of renal function in liver transplant alone versus combined liver kidney transplantation: analysis from the NHSBT UK registry

Introduction and Aims: Recovery of renal function after liver transplantation is strongly influenced by pretransplant degree and duration of renal insufficiency, despite imprecise methods for measuring renal dysfunction. Indications for combined liver-kidney transplantation (CLKT) have been defined, but these are still under debate and hepatorenal syndrome (HRS) is a particularly challenging condition given the hardly predictable spontaneous improvement with liver transplant alone (LTA). Methods: We analysed data of 6035 patients (Jan 2001-Dec 2012) from NHSBT UK Transplant Registry. Renal function at 1 years after transplantation was compared between CLKT and LTA with stratification on the basis of glomerular filtration rate (eGFR) at transplant (KDIGO Guidelines) and treatment with renal replacement therapy (RRT). Renal function post-transplantation was classified as eGFR &gt;60, between 59-30 and &lt;30 ml/min/1.73m2, the latter identified as non recovery of renal function. Univariate and multivariable analysis were performed. Results: 5912 patients (98.0%) underwent liver transplant alone (LTA) and 123 (2.0%) patients received a CLKT. 305 (5.2%) of the LTA group were on RRT at time of transplantation, compared to 72 (58.5%) of the CKLT group. No patient with a MELD score &lt;20 received RRT before transplant. No patients with eGFR ≥60 mL/min/1.73m2 received CLKT. 27% of patients receiving CLKT were diagnosed with pre-transplant glomerular/tubular kidney disease, 39% with polycystic disease and 34% were not specified. LTA patients on RRT were more frequently presenting ascites ( p&lt;0.001), variceal bleeding ( p=0.002), higher MELD score ( p&lt;0.001), higher INR ( p&lt;0.001) and bilirubin at transplant ( p&lt;0.001), suggesting the occurrence of HRS (data not available). Patients on RRT experience a significant difference of renal function recovery at 1 year post-transplant when receiving LTA versus CLKT, with the latter group experiencing a higher percentage of non-recovery ( p=0.001; table 1). This difference was not detected for other eGFR stratifications.The univariate analysis identified recipient age &gt;50 years, female gender, RRT in patients with MELD &gt;20, polycystic disease and diabetes as predictive factors for non-recovery of renal function in patients undergoing LTA. In a multivariable model including all clinically relevant variables simultaneously, the independent predictors of renal function non-recovery were female gender (HR 2.76; 95% CI 1.52-4.99, p=0.001), RRT in patients with MELD &gt;20 (HR 3.62; 95% CI 1.44-9.08, p=0.006) and diabetes (HR 2.55; 95% CI 1.38-4.73, p=0.003). Conclusions: Recovery of renal function post-LTA is acceptable for patients with different stratifications of eGFR pre-transplant. RRT, female gender and diabetes may suggest to perform CLKT

Vacuum-Induced Surface Freezing for the Freeze-Drying of the Human Growth Hormone: How Does Nucleation Control Affect Protein Stability?

Abstract In the present work, the effect of controlled nucleation on the stability of human growth hormone (hGH) during freeze-drying has been investigated. More specifically, the vacuum-induced surface freezing technique has been compared to conventional freezing, both with and without an annealing step. Size exclusion chromatography and cell-based potency assays have been used to characterize the formation of soluble aggregates and the biological activity of hGH, respectively. The results obtained indicate that controlled nucleation has a positive effect on both cycle performance and product homogeneity because of the formation of bigger ice crystals, and characterized by a narrower dimensional distribution. From the point of view of hGH stability, we observed that vacuum-induced surface freezing is not detrimental to the biological activity of the protein, or aggregate formation. In addition, the effect of 2 different formulations, including trehalose or cellobiose, on protein preservation was also considered for this study