Models of information systems devoted to medical-imaging labs: an experience in the CNR clinical physiology institute

At the end of the 1990s, the SPERIGEST project, supported by the Italian Health Ministry, and fully developed at the Institute of Clinical Physiology, established an operative integrated clinical and healthcare information system. Continuously evolving and dynamically optimising procedures and protocols solve problems of: harmonisation of instrumentation of different brands; management of multimedia data provided by different medical imaging labs; satisfaction of both clinical and research needs; legal and economical requirements; user-friendship of the system. A ten years experience shows positive approach by medical and healthcare operators, coordinated activity, higher efficiency, simplified procedures, major concentration on medical decision-making

Information systems for medical imaging labs: the experience of the CNR Clinical Physiology Institute

In the late 1990s the CNR Clinical Physiology Institute was entrusted with the "SPERIGEST" project, granted by the Italian Health Ministry. Among the technical challenges of the project, the following issues were faced: 1) the definition of a system architecture able to conjugate a centric view, as required by data integration needs, with flexibility and modularity in order to satisfy the different healthcare environments; 2) the creation of local information systems devoted to the management of each single laboratory activity; 3) the creation of a suitable network to exchange information both inside and outside the hospital; 4) the overcoming of safety and security issues in the treatment of healthcare data; 5) the data processing for extracting knowledge from the archived data and for supporting the diagnostic/treatment process; 6) the education of healthcare personnel; 7) the adoption of standards for both storage and distribution of data. An hospital information system was developed according to a three layers mode

Information systems for the management of clinical, administrative and government data of clinical imaging laboratories

Integrated network-based medical information systems are in continuous development an d evolution, furthered by the ongoing technology: the aim is to limit healthcare expend iture, while facing the increase of the demand of health services, as a result of the improvement of socialeconomic conditions, ageing of the population, and progress in medical knowledge and technologies. Today the discipline of OHealth Informaticso takes care of the design and the impleme ntation of information systems, to provide to the organization, processing, integration, storage, distribution and management, of the clinical and administrative data

Information systems for medical imaging labs: the experience of the CNR Clinical Physiology Institute

Local information systems, devoted to the management of the clinical and healthcare activity in laboratories for biomedical imaging, has been realized in IFC. Herein is a presentation of the main results obtained after a ten years development and employment of such a complex information system

Models of Information Systems devoted to Medical Imaging Labs: an experience in the CNR Clinical Physiology Institute

abstract for the paper presentation about the decennal experience at IFC on information systems developped for medical imaging labsabstract per la presentazione relativa alla decennale esperienza presso IFC sui sistemi informativi sviluppati per uso dei laboratori dedicati all\u27imaging clinico e di ricerca medic

Information Systems for the Management of Clinical, Administrative and Government Data of Clinical Imaging Laboratories

The integrated clinical and healthcare information system, developed at the CNR Clinical Physiology Institute, undergoes to updated and upgraded procedures and protocols, by solving problems of: harmonization of instrumentation of different brands; management of multimedial data provided by different medical imaging labs; satisfaction of both clinical and research needs as well as legal and economical requirements; user-friendship of the provided tools. Peculiar attention has been paid to the management of the laboratories devoted to biomedical imaging: medical and healthcare operators have coworked with engineers, to get a system able to guarantee coordinated activity, higher efficiency, simplified procedures, major concentration onto the medical decision-making issues, by supporting conventional techniques as well as new hybrid imaging technologies.Il sistema informativo per uso clinico e sanitario, sviluppato presso l\u27Istituto di Fisiologia Clinica del CNR, e\u27 in continuo aggiornamento e sviluppo di procedure e protocolli, che risolvano problemi relativi a: armonizzazione di strumentazione prodotta da diversi marchi commerciali e non; gestione dei dati multimediali forniti dai vari laboratori di imaging clinico; soddisfazione delle esigenze di ricerca e cliniche nonche\u27 deei requisiti di legalita\u27 ed economicita\u27; facilita\u27 d\u27uso degli strumenti proposti all\u27utente. Particolare attenzione e\u27 stata dedicata al "governo" dei laboratori di imaging medicale, e i vari operatori sanitari hanno collaborato con quelli tecnologici per realizzare un sistema capace di garantire un\u27attivita\u27 coordinata, piu\u27 elevata efficienza, procedure semplificate, maggiore concentrazione sulla "decisione" medica, sia dando sostegno alle tradizionali tecniche di acquisizione che alle innovative tecniche ibride

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Parameters derived by ultrasonic myocardial characterization in dialysis patients are associated with mortality

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Segmentation of lung fields in digital chest radiographs by artificial neural networks

Lung field segmentation is a basic step for virtually any quantitative procedure. In this view, due to the imaging process and the complexity of the imaged district, an efficient use of prior anatomical knowledge is crucial. In this report we describe a new approach to lung field segmentation which is based on fuzzy boundary modeling and a neural network architecture including supervised multilayer networks and topology preserving maps

Myeloperoxidase modulation by LDL apheresis in Familial Hypercholesterolemia

<p>Abstract</p> <p>Background</p> <p>Myeloperoxidase (MPO) is a marker of plaque vulnerability and a mechanistic bridge between inflammation and cardiovascular disease, and thus is a suitable target for therapeutic strategy against cardiovascular disease.</p> <p>Methods</p> <p>Since hypercholesterolemia is associated with atherosclerosis and inflammation, we tested whether MPO serum levels were up-regulated in Familial Hypercholesterolemia (FH) and whether acute reduction of total cholesterol (TC) would also reduce MPO concentration. FH subjects undergoing LDL-apheresis (LDL-A) treatment are a paradigmatic clinical model where TC rapidly plunges from extremely high to extremely low levels after selective LDL removal, and then spontaneously rebounds to baseline conditions. This clinical setting allows multiple intra-patient observations at different plasma TC concentrations. We measured MPO levels in serum by ELISA tests, and in peripheral leukocytes by immunofluorescence, to learn whether they were affected by the changes in TC levels. Serum MPO was measured before and serially up to the 14^thday following LDL-A.</p> <p>Results</p> <p>In both serum and peripheral leukocytes, MPO concentrations were <it>i) </it>higher than in sex- and age-matched healthy controls (<it>p </it>< 0.01); <it>ii) </it>decreased with TC reduction; <it>iii) </it>parallel with TC time course; <it>iv) </it>correlated with plasma TC. At regression analysis, plasma TC was the only variable considered that influenced MPO serum levels (<it>β </it>0.022 ± 0.010, <it>p </it>< 0.0001).</p> <p>Conclusions</p> <p>In FH the MPO serum levels were modulated through changes in the TC concentrations carried out by LDL-A. Further study is needed to determine whether reduced MPO levels obtained by LDL-A could have any therapeutic impact.</p