8,395 research outputs found
Black Hole Production by Cosmic Rays
Ultra-high energy cosmic rays create black holes in scenarios with extra
dimensions and TeV-scale gravity. In particular, cosmic neutrinos will produce
black holes deep in the atmosphere, initiating quasi-horizontal showers far
above the standard model rate. At the Auger Observatory, hundreds of black hole
events may be observed, providing evidence for extra dimensions and the first
opportunity for experimental study of microscopic black holes. If no black
holes are found, the fundamental Planck scale must be above 2 TeV for any
number of extra dimensions.Comment: 4 pages, 4 figures, PRL versio
Fractal Conductance Fluctuations in a Soft Wall Stadium and a Sinai Billiard
Conductance fluctuations have been studied in a soft wall stadium and a Sinai
billiard defined by electrostatic gates on a high mobility semiconductor
heterojunction. These reproducible magnetoconductance fluctuations are found to
be fractal confirming recent theoretical predictions of quantum signatures in
classically mixed (regular and chaotic) systems. The fractal character of the
fluctuations provides direct evidence for a hierarchical phase space structure
at the boundary between regular and chaotic motion.Comment: 4 pages, 4 figures, data on Sinai geometry added to Fig.1, minor
change
Extreme events in multilayer, interdependent complex networks and control
This work was supported by NSF under Grant No. 1441352.Peer reviewedPublisher PD
Mechanical properties of mesoporous ceria nanoarchitectures
Architectural constructs are engineered to impart desirable mechanical properties facilitating bridges spanning a thousand meters and buildings nearly 1 km in height. However, do the same 'engineering-rules' translate to the nanoscale, where the architectural features are less than 0.0001 mm in size? Here, we calculate the mechanical properties of a porous ceramic functional material, ceria, as a function of its nanoarchitecture using molecular dynamics simulation and predict its yield strength to be almost two orders of magnitude higher than the parent bulk material. In particular, we generate models of nanoporous ceria with either a hexagonal or cubic array of one-dimensional pores and simulate their responses to mechanical load. We find that the mechanical properties are critically dependent upon the orientation between the crystal structure (symmetry, direction) and the pore structure (symmetry, direction). This journal i
Ethanol Exposure Alters Protein Expression in a Mouse Model of Fetal Alcohol Spectrum Disorders
Alcohol exposure during development can result in variable growth retardation and facial dysmorphology known as fetal alcohol spectrum disorders. Although the mechanisms underlying the disorder are not fully understood, recent progress has been made that alcohol induces aberrant changes in gene expression and in the epigenome of embryos. To inform the gene and epigenetic changes in alcohol-induced teratology, we used whole-embryo culture to identify the alcohol-signature protein profile of neurulating C6 mice. Alcohol-treated and control cultures were homogenized, isoelectrically focused, and loaded for 2D gel electrophoresis. Stained gels were cross matched with analytical software. We identified 40 differentially expressed protein spots (P < 0.01), and 9 spots were selected for LC/MS-MS identification. Misregulated proteins include serotransferrin, triosephosphate isomerase and ubiquitin-conjugating enzyme E2 N. Misregulation of serotransferrin and triosephosphate isomerase was confirmed with immunologic analysis. Alteration of proteins with roles in cellular function, cell cycle, and the ubiquitin-proteasome pathway was induced by alcohol. Several misregulated proteins interact with effectors of the NF-κB and Myc transcription factor cascades. Using a whole-embryo culture, we have identified misregulated proteins known to be involved in nervous system development and function
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