Using General Anesthesia plus Muscle Relaxant in a Patient with Spinal Muscular Atrophy Type IV: A Case Report

Spinal muscular atrophy (SMA) is a rare genetic disease characterized by degeneration of spinal cord motor neurons, which results in hypotonia and muscle weakness. Patients with type IV SMA often have onset of weakness from adulthood. Anesthetic management is often difficult in these patients as a result of muscle weakness and hypersensitivity to neuromuscular blocking agents as shown by (Lunn and Wang; 2008, Simic; 2008, and Cifuentes-Diaz et al.; 2002). Herein we report a case of anesthetic management of a patient with SMA type IV for mammectomy and review some other cases of SMA patients receiving different kinds of anesthesia

Amplifying Frequency Up-Converted Infrared Signals with a Molecular Optomechanical Cavity

Frequency up-conversion, enabled by molecular optomechanical coupling, has recently emerged as a promising approach for converting infrared signals into the visible range through quantum coherent conversion of signals. However, detecting these converted signals poses a significant challenge due to their inherently weak signal intensity. In this work, we propose an amplification mechanism capable of enhancing the signal intensity by a factor of 1000 or more in a molecular-cavity system consisting $10^{7}$ molecules. The mechanism takes advantage of the strong coupling enhancement with molecular collective mode and Stokes sideband pump. Our work demonstrates a feasible approach for up-converting infrared signals to the visible range.Comment: 5 pages, 4 figures for the main text; 6 pages, 2 figures for Supplementary Materia

2,4-Dibromo-6-{(E)-[(R)-1-phenyl­ethyl]imino­meth­yl}phenol

In the title Schiff base, C15H13Br2NO, the benzene and phenyl rings form a dihedral angle of 75.18 (13)°. The N=C bond length of 1.263 (6) Å is shorter than of the N—C bond [1.476 (5) Å], indicating a double bond. In the crystal, there is some pseudosymmetry. This occurs because most of the two mol­ecules are centrosymmetrically related. The mol­ecular structure is stabilized by intra­molecular O—H⋯N hydrogen bonds

catena-Poly[[(2,2′-bipyridine-κ2 N,N′)copper(I)]-μ-cyanido-κ2 C:N-[(2,2′-bipyridine-κ2 N,N′)copper(I)]-μ-thio­cyanato-κ2 S:N]

The title compound, [Cu2(CN)(SCN)(C10H8N2)2]n, contains two crystallographically independent CuI atoms, each in a distorted tetra­hedral geometry. Each Cu atom is coordinated by a bidentate chelating 2,2′-bipyridine ligand. A bridging cyanide anion links the two Cu(2,2′-bipyridine) units to form a binuclear unit. Adjacent binuclear units are connected by a thio­cyanate anion into a one-dimensional helical chain along [010]. The cyanide anion is disordered, with each site occupied by both C and N atoms in an occupancy ratio of 0.61 (5):0.39 (5). The S atom of the thio­cyanate anion is also disordered over two sites, with occupancy factors of 0.61 (3) and 0.39 (3). There are π–π inter­actions between the pyridyl rings of neighbouring chains [centroid–centroid distance = 3.82 (1) Å]

Preparation and characterization of hexadecyltrimethylammonium bromide modified nanocrystalline cellulose / graphene oxide composite thin film and its potential in sensing copper ion using surface plasmon resonance technique

In this study, the preparation of hexadecyltrimethylammonium bromide modified nanocrystalline cellulose/graphene oxide composite (CTA-NCC/GO) solution under mild condition has been described. The CTA-NCC/GO thin film then was prepared by spin coating technique. Moreover, the CTA-NCC/GO thin film was characterized by Fourier transform infrared spectroscopy (FTIR) and atomic force microscopy (AFM) for the structural properties while the optical properties were characterized by ultraviolet-visible (UV–vis). FTIR confirmed the functional group that is contained in CTA-NCC/GO thin film and the surface morphology obtained from AFM results showed that the thin film is homogenous. The UV–vis analysis also showed that CTA-NCC/GO thin film has high absorption with optical band gap of 4.00 eV. Furthermore, the CTA-NCC/GO thin film has been studied to be incorporated with surface plasmon resonance spectroscopy (SPR) to detect copper ion. The SPR results showed that copper ion can be detected as low as 0.01 ppm using this thin film