262 research outputs found
Parity-dependent State Engineering and Tomography in the ultrastrong coupling regime
Reaching the strong coupling regime of light-matter interaction has led to an
impressive development in fundamental quantum physics and applications to
quantum information processing. Latests advances in different quantum
technologies, like superconducting circuits or semiconductor quantum wells,
show that the ultrastrong coupling regime (USC) can also be achieved, where
novel physical phenomena and potential computational benefits have been
predicted. Nevertheless, the lack of effective decoupling mechanism in this
regime has so far hindered control and measurement processes. Here, we propose
a method based on parity symmetry conservation that allows for the generation
and reconstruction of arbitrary states in the ultrastrong coupling regime of
light-matter interactions. Our protocol requires minimal external resources by
making use of the coupling between the USC system and an ancillary two-level
quantum system.Comment: Improved version. 9 pages, 5 figure
Scalable quantum memory in the ultrastrong coupling regime
Circuit quantum electrodynamics, consisting of superconducting artificial
atoms coupled to on-chip resonators, represents a prime candidate to implement
the scalable quantum computing architecture because of the presence of good
tunability and controllability. Furthermore, recent advances have pushed the
technology towards the ultrastrong coupling regime of light-matter interaction,
where the qubit-resonator coupling strength reaches a considerable fraction of
the resonator frequency. Here, we propose a qubit-resonator system operating in
that regime, as a quantum memory device and study the storage and retrieval of
quantum information in and from the Z2 parity-protected quantum memory, within
experimentally feasible schemes. We are also convinced that our proposal might
pave a way to realize a scalable quantum random-access memory due to its fast
storage and readout performances.Comment: We have updated the title, abstract and included a new section on the
open-system dynamic
Introduction: The New England Town Meeting: A Founding Myth of American Democracy
Notwithstanding notable exceptions, historical investigation is far from central in deliberative scholarship and even recent work on participatory research stresses the need for more historical work. The aim of our introduction to this collective volume is to assess and to draw attention to the contribution of historical analysis in the current scholarly debate on democracy, in particular regarding the ways in which participation and deliberation emerge and develop in New England’s famous town meetings. Town meetings have traditionally been cited as one of the fullest and earliest realizations of the idea of democratic government and of deliberation at work. Nowadays the great debate on deliberative and participatory democracy has contributed to restoring the town meetings as a symbol of democratic deliberation. The critical study of how one of the oldest and most inspiring forms of democratic participation has evolved is not only a fascinating endeavor in itself, it is also a unique opportunity to better understand how and to what extent these institutional practices, inspired by ideals of deliberation and participation, can support – or impede – the democratization of today’s societies
Design and synthesis of wm5 analogues as HIV-1 TAR RNA binders
The 6-aminoquinolone WM5, previously identified by us, is among the most selective small molecules known as TAR RNA binders to show anti-HIV activity. Methods: Starting from WM5, a series of analogues modified at N-1, C-6 or C-7 position was prepared by inserting guanidine or amidine groups as well as other protonable moieties intended to electrostatically bind the phosphate backbone of TAR. All the compounds were tested for their ability to inhibit HIV-1 replication in MT-4 cells and in parallel for their cytotoxicity. The active compounds were also evaluated for their ability to interfere with the formation of the Tat-TAR complex using a Fluorescence Quenching Assay (FQA). Results: Some of the synthesized compounds showed an anti-HIV-1 activity in the sub-micromolar range with the naphthyridone derivatives being the most potent. Three of the synthesized derivatives were able to interact with the Tat-TAR complex formation presenting Ki values improved as compared to the values obtained with WM5. Conclusion: The addition of a pyridine-based protonable side chain at the N-1 position of the quinolone/naphthyridone core imparted to the compounds the ability to interfere with Tat-TAR complex formation and HIV-1 replicatio
I linguaggi standard del W3C e gli strumenti Open Source per la gestione dei dati archeologici
Employment among Childhood Cancer Survivors: A Systematic Review and Meta-Analysis
To date, there are heterogeneous studies related to childhood cancer survivors’ (CCS) employment rates. Given the importance of this topic, we aimed to perform a systematic review and meta-analysis to investigate the prevalence of employment among CCS and to examine its association with socio-demographic and clinical factors. We followed the PRISMA guidelines to search for pertinent articles in relevant electronic databases. Eighty-nine articles comprising 93 cohorts were included. The overall prevalence of employment was 66% (CI: 95% 0.63–0.69). Subgroup meta-analyses showed that lower rates were found for central nervous system tumor survivors (51%, CI: 95% 0.43–0.59), and for CCS treated with cranial-radiotherapy (53%, CI: 95% 0.42–0.64) or haematopoietic stem-cell transplantation (56%, CI: 95% 0.46–0.65). The studies conducted in Asia highlighted employment rates of 47% (CI: 95%, 0.34–0.60). Univariate meta-regressions identified the following socio-demographic factors associated with higher rates of employment: a female gender (p = 0.046), a higher mean age at the time of investigation (p = 0.00), a longer time since diagnosis (p = 0.00), a higher educational level (p = 0.03), and a married status (p = 0.00). In conclusion, this systematic review and meta-analysis provides evidence that two-thirds of CCS are employed worldwide. Identifying vulnerable groups of CCS may allow for the design of multidisciplinary support strategies and interventions to promote employment in this population
Experimental preparation of Werner state via spontaneous parametric down-conversion
We present an experiment of preparing Werner state via spontaneous parametric
down-conversion and controlled decoherence of photons in this paper. In this
experiment two independent BBO (beta-barium borate) crystals are used to
produce down-conversion light beams, which are mixed to prepare Werner state.Comment: 6 pages, 4 figures and 2 table
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