ACUTE RESPIRATORY INFECTIONS PREVENTION AND TREATMENT IN CHILDREN

The article examines the aspects of clinical efficacy in prevention and treatment of acute respiratory infections and influenza by Arbidolum with direct anti-virus and indirect immunostimulating and interferon inducing effects. It outlines the results of various research studies that have proved the soundness of its application. A study involving 500 children that was conducted at the State Educational Institution of Higher Professional Education Russian State Medical University has proved the economic efficiency of regiments for treatment and prevention of ARI using this medication in sickly and chronic children.Key words: Arbidolum, antiviral agent, sickly children

ACUTE RESPIRATORY INFECTIONS PREVENTION AND TREATMENT IN CHILDREN

The article examines the aspects of clinical efficacy in prevention and treatment of acute respiratory infections and influenza by Arbidolum with direct anti-virus and indirect immunostimulating and interferon inducing effects. It outlines the results of various research studies that have proved the soundness of its application. A study involving 500 children that was conducted at the State Educational Institution of Higher Professional Education Russian State Medical University has proved the economic efficiency of regiments for treatment and prevention of ARI using this medication in sickly and chronic children.Key words: Arbidolum, antiviral agent, sickly children

ПРОФИЛАКТИКА И ЛЕЧЕНИЕ ОРИ У ДЕТЕЙ

The article examines the aspects of clinical efficacy in prevention and treatment of acute respiratory infections and influenza by Arbidolum with direct anti-virus and indirect immunostimulating and interferon inducing effects. It outlines the results of various research studies that have proved the soundness of its application. A study involving 500 children that was conducted at the State Educational Institution of Higher Professional Education Russian State Medical University has proved the economic efficiency of regiments for treatment and prevention of ARI using this medication in sickly and chronic children.Key words: Arbidolum, antiviral agent, sickly children.В статье рассмотрены аспекты клинической эффективности профилактики и лечения ОРИ и гриппа с применением Арбидола — препарата с прямым противовирусным действием и дополнительной иммуностимулирующей и интерферониндуцирующей активностью. Приведены результаты различных исследований, доказавших обоснованность его применения. Наблюдение, проведенное с участием 500 детей в ГОУ ВПО РГМУ, доказало экономическую эффективность схем лечения и профилактики ОРИ с применением данного препарата у часто и длительно болеющих детей. Ключевые слова: противовирусное средство, индуктор интерферона, часто и длительно болеющие дети.(Педиатрическая фармакология. – 2009;6(6): 92-97

The structure of interstitial lung diseases in children of the first two years of life

For the first time in Russia, the article provides data on interstitial lung diseases structure in children of the first two years of life, based on a series of observations of 68 patients with these rare diseases, as a part of multi-center ambispective study. Interstitial lung diseases in observed children included: Wilson-Mikity syndrome (23,4%), neuroendocrine hyperplasia of infancy (22%), bronchiolitis obliterans with organizing pneumonia (7,4%), primary pulmonary hypoplasia (1,5%), secondary pulmonary hypoplasia with Jeune syndrome (10,3%), secondary pulmonary hypoplasia with Edwards syndrome (2,9%), secondary pulmonary hypoplasia with other associated pathology (omphalocele - 1,5%, non-immune fetal hydrops - 1,5%), subpleural cysts in patients with Down syndrome (5,9%), congenital deficiency of surfactant protein B (1,5%), brain-lung- thyroid syndrome (2,9%), congenital alveolar-capillary dysplasia (1,5%), interstitial lung diseases with systemic diseases (Langerhans cell histiocytosis - 16,2%, Niemann-Pick disease - 1,5%). The article summarizes clinical features, the results of image diagnosis and disease outcomes. © 2015, Pediatria Ltd. All rights reserved

The structure of interstitial lung diseases in children of the first two years of life

For the first time in Russia, the article provides data on interstitial lung diseases structure in children of the first two years of life, based on a series of observations of 68 patients with these rare diseases, as a part of multi-center ambispective study. Interstitial lung diseases in observed children included: Wilson-Mikity syndrome (23,4%), neuroendocrine hyperplasia of infancy (22%), bronchiolitis obliterans with organizing pneumonia (7,4%), primary pulmonary hypoplasia (1,5%), secondary pulmonary hypoplasia with Jeune syndrome (10,3%), secondary pulmonary hypoplasia with Edwards syndrome (2,9%), secondary pulmonary hypoplasia with other associated pathology (omphalocele - 1,5%, non-immune fetal hydrops - 1,5%), subpleural cysts in patients with Down syndrome (5,9%), congenital deficiency of surfactant protein B (1,5%), brain-lung- thyroid syndrome (2,9%), congenital alveolar-capillary dysplasia (1,5%), interstitial lung diseases with systemic diseases (Langerhans cell histiocytosis - 16,2%, Niemann-Pick disease - 1,5%). The article summarizes clinical features, the results of image diagnosis and disease outcomes. © 2015, Pediatria Ltd. All rights reserved