33 research outputs found

    Current Noninvasive MR-Based Imaging Methods in Assessing NAFLD Patients

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    The chapter will focus on the different aspects of nonalcoholic fatty liver disease (NAFLD). An update in noninvasive MR-based imaging will be offered in detail, pointing mainly to fat, iron, and fibrosis deposition and the accuracy of quantitative methods in disease grading and severity assessment. NAFLD is the most common cause of chronic liver disease (CLD) in Western countries. MRI is used to evaluate the disease, to assess the severity, and to quantify the amount of fat deposition, being also the method of choice to evaluate and quantify iron overload. Diagnosis and staging of liver fibrosis is one of the most challenging aspects of noninvasive imaging. “Virtual biopsy” refers to the possibility of imaging techniques to depict, map, and measure fibrosis minimizing the need for invasive liver biopsies in CLD. MRI allows an accurate determination of steatosis, iron overload, and fibrosis, even if they coexist

    Strain Elastography in Invasive Lobular Carcinoma

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    Breast cancer remains the second cause of mortality in women, even if the mortality rates linked to it have drastically dropped at the present time. Invasive lobular carcinoma (ILC) accounts for 5–15% of the breast cancers and it is the second most encountered type among invasive carcinomas. There has been reported a high rate for bilateral lesions (6–47%), multifocality/multicentricity (21%), all affecting ILC overall survival. Due to its nonspecific symptoms and to the fact that it does not invoke a vigorous desmoplastic response and has a low likelihood of producing calcifications, the ILC tends to be insidious on mammography. Contrast enhanced MRI has the lowest false negative rate in detecting ILC and it is the most accurate method of determining the lesion extension, though it is expensive and not widely available. Therefore, the ultrasound (US) plays a significant role in the diagnosis of ILC. US elastography imaging (EI) individualizes malignant breast lesions with high sensitivity and specificity. Recent studies suggested that US elastography can even diagnose lobular cancers that have benign findings on conventional imaging. Goal: present various US aspects and exemplify the added diagnostic value of strain elastography—how it may change the BIRADS category and further therapeutic management

    CLINICAL EVALUATION OF EDENTULOUS PATIENTS USING COMPUTERIZED PROGRAMS OF SCORING

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    The purpose of this study is to show how a computerized program can improve medical reasoning for young practitioners and dental students, and to show to the patients the outcome of their treatment plan. Materials and methods: We used a computerized program, developed by Prof. Dr. Norina Forna, for medical reasoning in choosing a correct treatment plan, for partial edentulous patients, a program developed for dental students and young practitioners, that offers the best prosthetic solution according to clinical evaluation, general health, psychological, and economical status. We applied this program for a number of 305 patients treated in the Faculty of Dental Medicine, in the department of removable prosthetics, from 2010 until 2013. Results: For all the 305 patients treated we started clinical evaluation, general health evaluation, psychological evaluation and environmental evaluation. The results that we obtained showed that dental students do not have the holistic view over a case, that they regard only the clinical aspects, and less the general, psychological and environmental status of the patients, so they can easily obtain an incorrect solution for a case. The program offers indications by valuing all this parameters, and in regard of these offers a good, medium or poor prognosis for the case. This prognosis is extremely efficient for the patient also, for that he knows what to expect from his rehabilitation. Conclusions: A fully comprehensive computerized program is proven to be extremely efficient in adapting prosthetic rehabilitation to the patient, in order to obtain maximum of efficiency

    Urethral Mesh Assessment in Cancer Patients

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    Urethral mesh placement has become a common surgical intervention for the management of stress urinary incontinence. While this procedure offers significant benefits, it is not without potential complications. This review article aims to provide a comprehensive overview of urethral mesh assessment in oncologic patients. The article explores normal magnetic resonance imaging (MRI) and computed tomography (CT) mesh appearances and highlights the pathological aspects associated with urethral mesh complications including both short-term and long-term post-operative complications. By understanding the spectrum of normal findings of urethral mesh and the possible complications, clinicians can improve patient outcomes and make informed decisions regarding urethral mesh management in this patient population
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