Surgical Outcome in Laparoscopic Abdominal Surgical Operations with Clostridium Difficile Infection

Introduction: Postoperative Clostridium difficile infection (CDI) has associated morbidity, but it is unknown how it impacts different operations. We sought to determine the incidence and postoperative morbidity following abdominal surgery.Method: The National Surgical Quality Improvement Program database (2015-2019) was utilized to evaluate adult (≥18 years-old) patients who developed CDI following laparoscopic abdominal operations. Univariate and multivariate analysis were performed to evaluate outcomes.Results: A total of 973 338 patients were studied and the overall incidence of CDI was .3% within 30 days of operation. Colorectal surgery had the highest incidence of CDI (1601/167 949,1.0%) with significantly longer mean length of stay (LOS) (8.0 days± 9.0, P < .01) compared to other surgical procedures. CDI patients also had a longer mean length of stay (6.6± 8.0 vs 2.1 ± 3.6 days, P < .01) and increased mortality (1.8% vs .2%, AOR: 4.64, CI: 3.45-5.67, P < .01) compared to patients without CDI.Conclusions: This national analysis demonstrates that CDI is a significant complication following abdominal surgery and is associated with increased LOS and mortality. Furthermore, laparoscopic colorectal surgery appears to have the greatest risk of CDI. Future research is needed to determine the exact cause in order to decrease the incidence of CDI by reconsidering the protocol of antibiotic use within the high-risk population

Risk of Postoperative Venous Thromboembolism Among Pregnant Women

Venous thromboembolism (VTE) is a critical complication after surgery. Although pregnancy is a known risk factor of VTE, available data on the risk of postoperative VTE are scarce. Using the American College of Surgeons National Surgical Quality Improvement Program database between 2006 and 2012, we matched 2,582 pregnant women to 103,640 nonpregnant women based on age, race, body mass index, and modified Rogers score. Pregnant women, compared with matched nonpregnant women, experienced higher incidence of VTE (0.5% vs 0.3%; odds ratio 1.93, 95% confidence interval 1.1 to 3.37, p = 0.02). Pregnant women also showed higher risk of pneumonia, ventilator dependence ≥48 hours, bleeding, and sepsis than did the counterparts. In conclusion, pregnancy was associated with higher risk of VTE after surgery as well as other postoperative complications. The absolute risk difference was small, and careful evaluation against the potential risk and benefit should be given when surgical treatment is considered among pregnant women

Minimally invasive surgery for rectal cancer.

Minimally invasive surgical treatments for colon cancers have revolutionized surgical approaches and have been implemented broadly over the last two decades. On the other hand, robotic-assisted versus laparoscopic resections for rectal cancer and comparison of these minimally invasive approaches with the traditional open operation are controversial and challenging topics to discuss between the different surgical investigators. Recent published studies have shown somewhat differing data and results from randomized controlled and non-randomized trials comparing laparoscopic with open rectal resections as well as robotic-assisted with both open and laparoscopic approaches. The surgical approach for rectal cancer is a fascinating subject since there are several different endpoints which have been used to measure quality and outcome. Overall survival, disease free survival, and quality of life (QOL) are the most relevant endpoints of rectal cancer treatment. Among minimally invasive approaches, the robotic approach seems to be less invasive than conventional laparoscopic surgery (LS) and less than hand assisted approach due partly to the less traumatic intra-abdominal handling of tissues. A convincing clinical benefit of minimally invasive rectal cancer approaches could be due to diminished surgical stress response leading to reduced morbidity. For this review, we have performed a systematic review of rectal cancer surgical management focusing on minimally invasive approaches, focusing specifically on the latest results of randomized trials for robotic assisted and laparoscopic rectal cancer resection

Minimally invasive surgery for rectal cancer.

Minimally invasive surgical treatments for colon cancers have revolutionized surgical approaches and have been implemented broadly over the last two decades. On the other hand, robotic-assisted versus laparoscopic resections for rectal cancer and comparison of these minimally invasive approaches with the traditional open operation are controversial and challenging topics to discuss between the different surgical investigators. Recent published studies have shown somewhat differing data and results from randomized controlled and non-randomized trials comparing laparoscopic with open rectal resections as well as robotic-assisted with both open and laparoscopic approaches. The surgical approach for rectal cancer is a fascinating subject since there are several different endpoints which have been used to measure quality and outcome. Overall survival, disease free survival, and quality of life (QOL) are the most relevant endpoints of rectal cancer treatment. Among minimally invasive approaches, the robotic approach seems to be less invasive than conventional laparoscopic surgery (LS) and less than hand assisted approach due partly to the less traumatic intra-abdominal handling of tissues. A convincing clinical benefit of minimally invasive rectal cancer approaches could be due to diminished surgical stress response leading to reduced morbidity. For this review, we have performed a systematic review of rectal cancer surgical management focusing on minimally invasive approaches, focusing specifically on the latest results of randomized trials for robotic assisted and laparoscopic rectal cancer resection