54 research outputs found

    Attention deficit hyperactivity disorder symptoms and cannabis use after one year among students of the i-Share cohort

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    International audienceBackground. Cannabis use in university students is associated with academic achievement failure and health issues. The objective of the study was to evaluate the association between attention deficit hyperactivity disorder (ADHD) symptoms and cannabis use after 1 year among students according to previous cannabis use.Methods. Students in France were recruited from February 2013 to July 2020 in the i-Share cohort. 4,270 participants were included (2,135 who never used cannabis at inclusion and 2,135 who did). The Adult ADHD Self-Report Scale (ASRS) was used to assess ADHD symptoms at inclusion. Cannabis use frequency was evaluated 1 year after inclusion. Multinomial regressions were conducted to assess the association between inclusion ADHD symptoms and cannabis use after 1 year.Results. Increase in ASRS scores was linked with a greater probability to use cannabis after 1 year and to have a higher cannabis use frequency (once a year-once a month adjusted odds ratio [OR]: 1.24 (1.15-1.34), more than once a month adjusted OR: 1.43 (1.27-1.61)). Among participants who never used cannabis at inclusion, this association disappeared (once a year-once a month adjusted OR: 1.15 (0.95-1.39), more than once a month adjusted OR: 1.16 (0.67-2)) but remained in participants who ever used cannabis at inclusion (once a year-once a month adjusted OR: 1.17 (1.06-1.29), more than once a month adjusted OR: 1.35 (1.18-1.55)). onclusions. High levels of ADHD symptoms in students could lead to continued cannabis use rather than new initiations

    Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

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    AbstractUnderstanding SARS-CoV-2 transmission in higher education settings is important to limit spread between students, and into at-risk populations. In this study, we sequenced 482 SARS-CoV-2 isolates from the University of Cambridge from 5 October to 6 December 2020. We perform a detailed phylogenetic comparison with 972 isolates from the surrounding community, complemented with epidemiological and contact tracing data, to determine transmission dynamics. We observe limited viral introductions into the university; the majority of student cases were linked to a single genetic cluster, likely following social gatherings at a venue outside the university. We identify considerable onward transmission associated with student accommodation and courses; this was effectively contained using local infection control measures and following a national lockdown. Transmission clusters were largely segregated within the university or the community. Our study highlights key determinants of SARS-CoV-2 transmission and effective interventions in a higher education setting that will inform public health policy during pandemics.</jats:p

    STOICHIOMETRY DEPENDENCE OF ZEEMAN HYPERFINE INTERACTIONS IN Fe1+x Ti2(1+x)S4 (x = 0, 0.030, 0.052)

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    Le rôle de la méthode de préparation du traitement thermique et de la non stoechiométrie sur l'ordre cristallographique et les propriétés magnétiques du chalcogénure ternaire FeTi2S4, a été le sujet de contradictions ces dernières années. Afin de contribuer à l'étude de ces questions, nous avons pensé voir comment les paramètres mentionnés ci-dessus se reflètent dans les spectres Mössbauer. Les résultats obtenus entre 4,2 K et 300 K sont discutés par comparaison aux résultats cristallographiques et magnétiques antérieurs.The role of the method of preparation, of the heat treatment and of the non stoichiometry, on the crystallographic and magnetic ordering of the ternay chalcogenide FeTi2S4 is not well inderstood to date. In order to clarify these questions, or, at least, to give supplementary data for future discussions, we have looked how the parameters mentioned above are reflected in the Mössbauer spectra. The results obtained between 4.2 K and 300 K showed marked differences between stoichiometric and non stoichiometric samples, and small or no differences between the different heat treatments and the different methods of preparation, respectively, and are discussed in terms of crystallographic and magnetic ordering
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