475 research outputs found
Increasing Value for Money in Higher Education Development Cooperation A German Perspective Based on Project Coordinators’ Experiences
The concept value for money, usually defined as the three E’s (economy, efficiency and effectiveness), does not fully apply to projects in development cooperation. The paper on hand argues that the concept should not be perceived as economic benefit in monetary terms only. It encourages a qualitative approach defining value for money as a long-term effect of a project that can be reached by only a little more input of resources than usually available for development cooperation projects. Thus, the concept of value for money is closely connected to that of sustainability of a project. Recent studies show that German-African development cooperation in the field of higher education not always can live up to the expectations concerning sustainability (DAAD 2013 / Hansert et al. 2012). Based on the authors’ experiences with development projects aiming at higher education quality, this article critically reflects on development cooperation in higher education and identifies prerequisites which could foster a beneficial use of (monetary and non-monetary) input in development cooperation projects. As will be shown, critical evaluative thinking, joint project planning, realistic expectations and the acknowledgement of intercultural differences can be key to successful project work in development cooperation and thus can help to increase the value for money and sustainability alike. Keywords: higher education management, quality assurance, project management, international cooperation, development cooperatio
Interventional Left Atrial Appendage Closure: Focus on Practical Implications
Catheter-based left atrial appendage closure is an evolving therapy for the prophylaxis of thromboembolic complications in nonvalvular atrial fibrillation patients, which are ineligible for long-term oral anticoagulation. For this indication, it is recommended by the current European guidelines. This review of the existing literature should facilitate the understanding of the therapy’s practical implications. It presents a clinical approach toward a correct patient selection, gives an overview of the different devices and the procedural aspects, reflects differences and benefits between several postprocedural regimens for device surveillance as well as antithrombotic medication and rounds off with a summary of the relevant studies concerning efficacy and safety outcome measures
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Methodological considerations for implementing the U.S. Soil Conservation Service Land Evaluation and Site Assessment (LESA) System in Oregon, with special reference to Marion County, Oregon
Oregon land use specialists believe that the present
definitions of farm and forest land in the state planning
goals are too broad. This results in poor quality resource
lands being as strongly protected as those of top quality.
With persistent growth pressure on rural lands, a means to
distinguish among primary, secondary and nonresource lands
must be developed so that these areas may be zoned for the
uses for which they are best-suited.
The Oregon Land Conservation and Development Commission
established a Rural Lands Advisory Committee in 1985 to
study the resource lands problem. The committee is
considering using a form of the U.S. Soil Conservation
Service Land Evaluation and Site Assessment System to make
the distinction among resource categories. Based on the
experience of Marion County, Oregon, such an application of
the system appears to be feasible. At least five other
states have adopted some form of a statewide evaluation
system, but, such a system could be more difficult to
develop in Oregon because of the state's size, agricultural
diversity and complex land use planning process.
There are several ways in which the Land Evaluation and
Site Assessment System can be used in the Oregon land use
program. To be most effective, the system should be
developed and implemented at a regional or county level with
close supervision by the Department of Land Conservation and
Development. No matter what level of government is
responsible, there are a number of technical and political
issues that must be resolved before the system can be used
in the Oregon program. Resolution of the problems hinges on
thoughtful guidance by the Department and is necessary for
consistent and justifiable results
Cyanotoxins associated with macrophytes in Berlin (Germany) water bodies – Occurrence and risk assessment
Publisher Copyright: © 2022Fatal dog poisoning after uptake of neurotoxic cyanobacteria associated with aquatic macrophytes in Tegeler See (Berlin, Germany) raised concerns about critical exposure of humans, especially children, to cyanotoxins produced by macrophyte associated cyanobacteria during recreational activity. From 2017 to 2021 a total of 398 samples of macrophytes washed ashore at bathing sites located at 19 Berlin lakes were analysed for anatoxins, microcystins, and cylindrospermopsins, as were 463 water samples taken in direct proximity to macrophyte accumulations. Cyanotoxins were detected in 66 % of macrophyte samples and 50 % of water samples, with anatoxins being the most frequently detected toxin group in macrophyte samples (58 %) and cylindrospermopsins in water samples (41 %). Microcoleus sp. associated with the water moss Fontinalis antipyretica was identified as anatoxin producing cy-anobacterium in isolated strains as well as in field samples from Tegeler See. Anatoxin contents in macrophyte samples rarely exceeded 1 mu g/g macrophyte fresh weight and peaked at 9.2 mu g/g f.w. Based on established toxicological points of departure, a critical anatoxin content of macrophyte samples of 3 mu g/g f.w. is proposed. Five samples, all taken in Tegeler See and all associated with the water moss Fontinalis antipyretica, exceeded this value. Contents and concentra-tions of microcystins and cylindrospermopsins did not reach critical levels. The potential exposure risks to anatoxins for children and dogs are assessed and recommendations are given.Peer reviewe
Peripheral Ventricular Assist Devices in Interventional Cardiology: The Impella® Micro-Axial Pump
Coronary artery disease (CAD) presents an ever-growing burden on health systems especially in the Western world. While percutaneous coronary intervention (PCI) is feasible in increasingly complex CAD, certain patient groups possess a high risk for major cardiac adverse events (MACE) during PCI. Poor outcome is associated with significantly depressed left ventricular function, complexity of relevant lesions, and increasing incidence of pre-existing cerebrovascular comorbidities and poor pre-interventional status. However, these risk factors also translate into a high peri-operative risk for coronary artery bypass graft (CABG) rendering some of these patients inoperable. Peripheral ventricular assist devices (pVADs) are temporarily inserted axial or centrifugal pumps that support ventricular output during PCI. The Impella® micro-axial device (Abiomed, Danvers, Massachusetts, USA) is an easily implantable pVAD that may improve patient outcome during PCI in high-risk patients (termed “protected PCI”) and in patients with cardiogenic shock (CS). pVADs in general and the Impella® system in particular play important roles in interventional cardiology and its indications and use will likely expand in the future. This chapter outlines in detail the indications, applications, and future trends concerning the Impella® system. Practical advice is given on the correct implantation of the device
Variability of the microcystin synthetase gene cluster
Abstract In populations of Planktothrix, microcystin-producers and non-producers, which are morphologically identical, coexist. In order to develop a basis for the reliable detection of microcystin producers in field samples with polymerase chain reaction (PCR) based methods, we studied the presence and variability of eight regions of the mcy gene cluster in 46 Planktothrix strains, including both microcystin-producing and non-producing ones. PCR-amplification products for two mcy gene regions were also found in non-microcystin-producing strains, indicating the existence of natural mutants. PCR-products of the other regions studied were only detected in microcystin-producing strains. Two of these mcy-amplicons were variable in sequence and length. Four gene regions remained that were conserved and specific for microcystin-producing Planktothrix strains, and thus qualified to detect the respective chemotypes in environmental samples
Assessment of response to neoadjuvant radiochemotherapy with F-18 FLT and F-18 FDG PET/CT in patients with rectal cancer
Gamification in der Regionalplanung: ein Ansatz zur Aktivierung formeller Planungsstrategien
„Fortschritt! Deiner Gemeinde gelingt die Ansiedlung eines führenden Unternehmens als Cash Cow. Spiele
diese Karte, um eine beliebige weitere Karte abzulegen.“ Während formale Festlegungen und deren
zugrundeliegenden Abwägungsprozesse, wie in der Planung üblich, abstrakt und für Laien wie politische
Entscheidungsträgerinnen schwer verständlich sind, können spielbasierte Medien Sachverhalte kurz und
dennoch prägnant darstellen. Dies gilt sowohl für die Funktionsweise der Raumplanung auf verschiedenen
Ebenen und insbesondere die formelle Regionalplanung an sich, als auch für die tatsächlichen Folgen
kommunaler Untätigkeit oder des Konterkarierens regionaler Festlegungen, wie in diesem Beitrag dargelegt.
Während Gamification in der Planung bereits seit Jahren diskutiert wird, sieht die Planungsrealität (noch)
anders aus.1
In diesem Beitrag werden die Probleme formeller Regionalplanung generell und am Beispiel der
Region Stuttgart dargestellt. Bekannt als starke Wirtschaftsregion in Baden-WĂĽrttemberg mit Global Playern
wie Daimler, Porsche und Bosch, sieht sich auch die Region Stuttgart mit Herausforderungen fĂĽr deren
zukĂĽnftige Entwicklung konfrontiert, die sich im GroĂźen und Ganzen als Wachstumsschmerzen
zusammenfassen lassen. Es stehen sich Akteure der Regionalentwicklung, BĂĽrgerinnen und politische
Entscheidungsträger aus verschiedenen Kommunen in vielfältigen Konstellationen mit ihren Positionen und
Motivationen gegenĂĽber. Aufgrund der administrativen Kleinteiligkeit und des verbreiteten
Konkurrenzdenkens wird die regionale Entwicklung durch inter-kommunale Spannungen, Stagnation durch
saturierte „Wohlfühl“-Gemeinden sowie schlicht unsolidarisches öffentliches Handeln behindert. In diesem
Zusammenhang sind auch verstärkte Phänome wie NIMBY („not in my backyard”) oder BANANA („built
absolutly nothing anywhere near anbody”) zu nennen. Darüber hinaus stößt der formelle Regionalplan als
räumliches Gesamtkonzept, das die funktionalen Zusammenhänge der Region integriert berücksichtigen und
zwischen konkurrierenden Nutzungen vermitteln soll, häufig auf Unverständnis, Widerwillen oder gar
Gegenwind – mit entsprechend negativen Folgen für die Akzeptanz und Wertschätzung der Inhalte. Auch
wenn der Stuttgarter Regionalplan als starke Bremse fungiert und den Rahmen des Instruments durch
restriktive Regelungen ausschöpft, stößt er dennoch an seine Grenzen, da er nicht in der Lage ist, die
relevanten Akteure zu aktivieren und zum Handeln zu bewegen, um die wirtschaftliche Spitzenposition und
Lebensqualität der Region zu halten. Es fehlt daher unter anderem an unterstützenden, persuasiven
Instrumenten, um dessen Konzepte in politischen Entscheidungsprozessen ĂĽberzeugend zu vermitteln.
In diesem Beitrag wird ein spielbasierter Ansatz fĂĽr die oben skizzierte Problematik mit den Schwerpunkten
Mediation, Konsultation und Integration in politische Entscheidungsprozesse, welcher im Rahmen eines
Studienprojekts im Masterstudiengang „Stadt- und Regionalentwicklung“ an der Technischen Universität
Kaiserslautern entwickelt wurde, vorgestellt. Das Kartenspiel richtet sich an BĂĽrgerinnen sowie politische
Entscheidungsträger der Kommunen an der Schnittstelle zur Regionalplanung und bietet eine Möglichkeit,
regional relevante, aber schwer greifbare Sachverhalte wie politische Handlungsoptionen, planerische
Grundsätze sowie gutes und schlechtes regionales Handeln verständlich darzustellen und für eine breite
Zielgruppe herunterzubrechen. Dabei schlüpfen politische Entscheidungsträger in die Rolle von Gemeinden,
um deren zukĂĽnftige Entwicklung zu bestimmen, wobei ihnen auf 60 illustrierten Karten die Folgen
verschiedener (Nicht-) Handlungen und Trends aufgezeigt werden. Die sachlich bis humorvoll gestalteten
Motive umfassen sowohl Erfolge und RĂĽckschritte als auch einfache Stopp-, Sammel- und Aktionskarten.
Ebenso wird aufgezeigt, in welchen Praxisfeldern das entwickelte Kartenspiel eingesetzt werden kann
Comparison of peri and post-procedural complications in patients undergoing revascularisation of coronary artery multivessel disease by coronary artery bypass grafting or protected percutaneous coronary intervention with the Impella 2.5 device
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