9 research outputs found

    A modified procedure for naming 332 pictures and collecting norms: Using tangram pictures in psycholinguistic studies

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    International audienceTangram pictures are abstract pictures which may be used as stimuli in various fields ofexperimental psychology and are often used in the field of dialogue psychology. The present study provides the first norms for a set of 332 tangram pictures. These pictures were standardized on a set of variables classically used in the literature on cognitive processes, such as visual perception, language and memory: name agreement, image agreement, familiarity, visual complexity, image variability and age of acquisition. Furthermore, norms for concreteness were also provided owing to the influence of this variable on the processes involved in lexical production. Correlational analyses on all variables were performed on the data collected from French native speakers. This new set of standardized pictures constitutes a reliable database for researchers when they select tangram pictures. Given the abstract nature of tangram pictures, this paper also discusses the similarities and differences with the literature on line drawings, and highlights their value for dialogue psychology studies, for psycholinguistics studies and for cognitive psychology in general

    Cognitive decline in Huntington's disease expansion gene carriers

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    Reduced Cancer Incidence in Huntington's Disease: Analysis in the Registry Study

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    Background: People with Huntington's disease (HD) have been observed to have lower rates of cancers. Objective: To investigate the relationship between age of onset of HD, CAG repeat length, and cancer diagnosis. Methods: Data were obtained from the European Huntington's disease network REGISTRY study for 6540 subjects. Population cancer incidence was ascertained from the GLOBOCAN database to obtain standardised incidence ratios of cancers in the REGISTRY subjects. Results: 173/6528 HD REGISTRY subjects had had a cancer diagnosis. The age-standardised incidence rate of all cancers in the REGISTRY HD population was 0.26 (CI 0.22-0.30). Individual cancers showed a lower age-standardised incidence rate compared with the control population with prostate and colorectal cancers showing the lowest rates. There was no effect of CAG length on the likelihood of cancer, but a cancer diagnosis within the last year was associated with a greatly increased rate of HD onset (Hazard Ratio 18.94, p < 0.001). Conclusions: Cancer is less common than expected in the HD population, confirming previous reports. However, this does not appear to be related to CAG length in HTT. A recent diagnosis of cancer increases the risk of HD onset at any age, likely due to increased investigation following a cancer diagnosis
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