Results of ambulatory arterial blood pressure monitoring in children with obesity

Objectives: The relationship between obesity and essential hypertension is well known. In this study, we aimed to evaluate ambulatory arterial blood pressure monitoring of obese and non-obese children who had similar demographic characteristics.Materials and methods: Seventy one children and adolescents (n=39 obesity, n=32 controls) were studied. Blood pressure of the children were measured by 24 hour ambulatory blood pressure monitoring device.Results: Obese children had significantly higher mean blood pressure values (systolic 121.9±11.7 mmHg, diastolic 70.2±5.3 mmHg) than control subjects (systolic 109.3±6.7 mmHg, diastolic 65.1±4.6 mmHg, p<0.05). Also, daytime and nighttime systolic and diastolic blood pressures were higher in patients with obesity than controls (p<0.05). Distribution of dipping status was not different between groups (p>0.05). Blood pressure load was found to be increased in obese children compared to the controls (%13.6±12.9 and %2.6±3.4, respectively; p<0.05). Serum total cholesterol and LDL-cholesterol levels of obese children (181.1±33.4 and 131.1±23.1mg/dl) were significantly higher than those of the controls (134.3±11.1 and 103.3±14.2 mg/dl, p<0.05).Conclusions: Obesity in children and adolescents should not be regarded as variations of normality, but as abnormality with an extremely high risk for the development of hypertension and hyperlipidemia in adulthood

Hemolytic uremic syndrome

Haemolytic uremic syndrome (HUS) is a severe disease with microangiopathic anemia, thrombocytopenia and leading cause of acute renal failure in children. Several etiological factors causing to HUS have been identified, like infections, genetic mutations, drugs, systemic diseases. In this review, we present the new classification of the disease, detailed information about pathogenesis, diagnostic methods and therapeutic approaches

Influence of Sowing Dates on Grain Yield and Some Cluster Properties of Quinoa (Chenopodium quinoa Willd.) Under Harran Plain Conditions

Quinoa (Chenopodium quinoa Willd.) is grown for its tiny edible seeds. Its seeds are high in protein and fiber. The seeds are also high in fiber and oil and are a good source of iron, magnesium, phosphorus, potassium, calcium, zinc, copper, vitamin E, and a number of antioxidants. The plants are also frost-resistant, salt-tolerant, and can be grown in poor soils. Quinoa can be used in any number of sweet or savoury dishes and is commonly boiled like rice or ground as a flour to fortify baked goods. In recently, quinoa growing and consumption are increasing day by day in the world. This study was aimed to determine different sowing dates on the grain yield and some cluster and kernel properties of quinoa under Harran Plain Conditions. Research was conducted according to randomized complete blocks design with three replicates in Harran plain conditions in 2016, Sanliurfa, Turkey. Q-52 Quinoa (Chenopodium quinoa Willd.) variety was used as plant material. In the study 9 different sowing dates were used such as 15 February, 1 March, 15 March, 1 April, 15 April, 1 May, 15 May, 1 June and 15 June. As a result of the research%253B statistically significant differences were seen between sowing dates at tested characteristics (Ple%253B0.01). Cluster number of plant ranged from 10.3 to 16.0 numbers, branches number of main clusters from 18.0 to 32.3 numbers and main cluster length from 31.6 to 46.2 cm. Thousand kernel weights were between 2.325 g. and 2.426 g, hectoliter weight between 69.17 and 69.83 kg hl-1 and grain yield 168.0 kg da-1 and 226.8 kg da-1. It was seen that tested characteristics generally increased from 15 February to 1 April sowing dates, but after 1 April sowing dates decreased. The highest grain yield was obtained from 1 April sowing date with 226.8 kg da-1 whereas the lowest grain yield was seen at June 15 sowing date with 168.8 kg da-1

Impact of Sowing Dates on Forage Value of Quinoa (Chenopodium quinoa Willd.) Under Semi-arid Conditions

This study was aimed to determine forage value of quinoa at the different sowing dates under semi-arid conditions. Research was conducted according to randomized complete blocks design with three replicates in Harran plain conditions in 2016, Sanliurfa, Turkey. Q-52 Quinoa (Chenopodium quinoa Willd.) variety was used as plant material. In the study 9 different sowing dates were used such as 15 February, 1 March, 15 March, 1 April, 15 April, 1 May, 15 May, 1 June and 15 June. In the research plant height, stem diameter, number of branches per plant, biomass yield, dry forage yield and harvest index were investigated. As a result of the research, statistically significant differences were seen between sowing dates at tested characteristics (Ple%253B0.01). As a result of the research, statistically significant differences were seen between sowing dates at tested characteristics (Ple%253B0.01). Plant height ranged from 81.8 cm to 109.4 cm, stem diameter from 9.0 mm to 12.6 mm, number of branches per plant from 10.3 to 12.7 number. The highest biomass yield was obtained from 1 April sowing date with 1751.40 kg da-1 whereas the lowest biomass yield was seen at June 15 sowing date with 1295.28 kg da-1. Dry matter yield values were between 415.8 (15 February) and 546.88 kg da-1 (1 April). Harvest index values were between 39.3%25 and 42.0%25. Quinoa yield characteristics in generally increased from 15 February to 1 April sowing dates, but after 1 April sowing dates decreased. Higher values were obtained from April and May sowing dates. The most suitable planting date for quinoa plant in semi-arid climatic conditions was determined as 1 April and can be recommended in similar ecologies

Vitamin D Deficiency and Insufficiency in Obese Children and Adolescents and Its Relationship with Insulin Resistance

Objectives. We aimed to determine the relationship between insulin resistance and serum 25-hydroxyvitamin D (25-OHD) levels in obese children and their nonobese peers. Materials and Methods. Included in the study group were 188 obese children (aged 9–15 years), and 68 age- and gender-matched healthy children of normal weight as control group. Anthropomorphic data were collected on patients and fasting serum glucose, insulin, serum lipids, alanine aminotransaminase (ALT) and 25-OHD were measured. The homeostatic model assessment of insulin resistance (HOMA-IR) was calculated in both groups. Results. The levels of 25-OHD in the obese group were significantly lower than those of the nonobese (). HOMA-IR, triglycerides, low-density lipoprotein, and ALT levels in the obese group were significantly higher than values of control group ( and , resp.). In the obese group, vitamin D deficiency, insufficiency, and sufficiency (25-OHD 10 ng/dl; > 20 ng/dl, resp.) were not correlated with HOMA-IR (, ). HOMA-IR was negatively correlated with BMI, BMI SDS, and BMI%, and triglycerides, low-density lipoprotein, and ALT levels (). Conclusion. The insulin resistance of the obese subjects who were vitamin D deficient and insufficient did not statistically differ from those with vitamin D sufficiency. Low 25-hydroxyvitamin D levels were not related with higher insulin resistance in obese children and adolescents. In obese subjects, insulin resistance was affected more from BMI, BMI SDS, and BMI% than from 25-hydroxyvitamin D levels

Acute tumor lysis syndrome secondary to a single-dose methylprednisolone in acute lymphoblastic leukemia

[No Abstract Available

The different cutaneous presentations in three cases of Kawasaki disease as confounding factor of diagnosis

WOS: 000386138300031PubMed ID: 27654745We report three paediatric cases of Kawasaki disease (KD). Erythema multiforme (EM) was the presenting cutaneous feature in two patients, with young age (43 days old), macular rash and meningitis in the third patient. Diagnosis of KD was difficult due either to initial misdiagnosis of drug eruption, incomplete presentation, or the young age of the patient. Clinicians should be aware of these cutaneous presentations to prevent KD complications

The Importance of Mean Platelet Volume in Children with Nephrotic Syndrome

Objective: The importance of mean platelet volume (MPV) in chronic inflammation was demonstrated in many dis­eases. We aimed to evaluate the role of MPV in nephrotic syndrome of childhood and relation with steroid response. Methods: We enrolled 59 children with nephrotic syndrome (24 steroid-resistance and 35 steroid-sensitive) and 34 healthy controls into the study. We evaluated total cholesterol, proteinuria, CRP, and albumin from study group and MPV and platelet count from both control and study group. Results: MPV level was higher in children with nephrotic syndrome when compared with control (8.6 ± 1.39 fl versus 7.09 ± 0.96 fl, p<0.001). Also platelet count was elevated in study group (406.092 ± 125.891 / μl versus 321.382 ± 78.666 / μl, p<0.001). MPV level and platelet count was similar in control and study subjects (p=0.798 and p=0.56). Conclusion: We demonstrated elevated MPV and platelet count in children with nephrotic syndrome. MPV is cheap, simple and important method to demonstrate platelet activation in nephrotic syndrome