Modeling factors of environmental tourism development in innovation economy

© Foundation Environmental Protection & Research-FEPR. The factors’ modeling of ecological tourism development in innovative economy is carried out in the article. The relevance of the article is due to the fact that the issues of the services industry’s development, especially in the field of ecological tourism, have not yet been fully resolved and require additional study and systematization of the factors determining them, which is especially important in the conditions of formation and development of the service economy in Russia. The purpose of the article is to systematize the factors of ecological tourism sector development from the position of cluster development of territories and evaluation of entrepreneurial potential in this area. The main research methods used in the article are description, comparison, generalization, analysis and synthesis, descriptive and cluster analysis. The clustering of Russia’s regions in five groups with similar socio-economic characteristics was carried out on the basis of cluster analysis in terms of paid services’ volume in the ecotourism market, real incomes of the population, per capita income of the population, profitability of goods sold in the industrial sector, innovative activity of organizations. The article systematizes the data of organizations’ business activity in the sphere of services in the field of ecological tourism, identifies the key drivers and inhibitors of entrepreneur confidence of business entities in the sector of the economy specializing in the provision of services in the field of ecological tourism. The materials of the article can be used in the development of measures to improve the efficiency of the service sector of the economy and eco-tourism, taking into account socio-economic trends in the innovation economy

Integrated management of flows in petroleum products supply chains in the field of hydrocarbons deep processing

© 2016, Econjournals. All rights reserved.The urgency of the problems stated in the article is reasoned by the fact that the requirements on the supply chain management system in the petrochemical industry become high on the basis of an integrated logistics concept. The purpose of the article is to develop methods to systematize the advantages of an integrated model of the petroleum products’ supply chain. The leading approach to the study of this problem is the modeling method that allows assessing of the effectiveness of petroleum products’ integrated supply chains. The article presents an analytical review of petroleum products’ market development in the Tatarstan Republic. The content of integrated control of flows in the supply chain of petroleum products in the field of hydrocarbons’ deep processing is disclosed. The submissions of the article have theoretical and practical significance for the development of models of the integrated supply chains management in the petrochemical industry

Integrated Management of Flows in Petroleum Products Supply Chains in the Field of Hydrocarbons Deep Processing

The urgency of the problems stated in the article is reasoned by the fact that the requirements on the supply chain management system in the petrochemical industry become high on the basis of an integrated logistics concept. The purpose of the article is to develop methods to systematize the advantages of an integrated model of the petroleum products' supply chain. The leading approach to the study of this problem is the modeling method that allows assessing of the effectiveness of petroleum products' integrated supply chains. The article presents an analytical review of petroleum products' market development in the Tatarstan Republic. The content of integrated control of flows in the supply chain of petroleum products in the field of hydrocarbons' deep processing is disclosed. The submissions of the article have theoretical and practical significance for the development of models of the integrated supply chains management in the petrochemical industry. Keywords: Supply Chain, Industry, Petroleum Products, Integrated Management, Petrochemical and Gas Complex. JEL Classifications: F15, L22, M11

Взаимосвязь спектроскопических и структурных свойств j-агрегатов индоцианина зеленого

Indocyanine green (ICG), when in free form in a liquid, can form stable nanoparticle structures or colloidal solution, while changing its spectroscopic properties. In the work, the aggregation degree and the average size of nanoparticles depending on the concentration of a colloidal solution of indocyanine green (ICG NPs) in the form of J-aggregates were investigated by various methods based on light scattering. The size of nanoparticles is an important parameter from the point of view of clinical application, because the technique of intravenous administration of drugs, in order to avoid microvascular thrombosis and embolism, provides dosage forms with inclusions of individual molecules or their clusters, not exceeding 500 nm diameter. In turn, small nanoparticles less than 30 nm lead to prolonged circulation of the drug in the body with an increased possibility of permeation into cells of healthy tissue. In the course of studies, it was found that an increase in the concentration of ICG NPs in the solution leads to an increase in the average size of spontaneously formed J-aggregates, which, in turn, leads to a decrease in the absorption coefficient in the aggregates. Presumably, this phenomenon, i.e. the established nonlinear dependence of the J-aggregate absorption on its size, can be explained by the formation of absorption centers on the J-aggregate surface in the form of mobile surface molecules. The threshold range of ICG molecule concentration was determined, at which there is a transition from aggregation with an increase in size with a slow addition of ICG J-aggregate molecules in height to a rapid addition in width.Индоцианин зеленый (ICG), находясь в растворе, способен образовывать стабильные структуры наночастиц или коллоидный раствор, изменяя при этом свои спектроскопические свойства. В работе различными методами, основанными на светорассеянии, были исследованы степень агрегации и средний размер наночастиц в зависимости от концентрации коллоидного раствора наночастиц индоцианина зеленого (ICG NPs) в форме J-агрегатов. Размер наночастиц представляет собой важный параметр с точки зрения клинического применения, так как техника внутривенного введения препаратов, с целью избежания тромбозов микрососудов и эмболии, предусматривает лекарственные формы с включениями, в виде отдельных молекул или их кластеров, не превышающими в диаметре 500 нм. С другой стороны, наночастицы размером менее 30 нм длительно циркулируют в организме и могут проникать в клетки здоровой ткани. В ходе исследований, было установлено, что увеличение концентрации ICG NPs в растворе ведет к увеличению среднего размера спонтанно формируемых J-агрегатов, что в свою очередь ведет к уменьшению коэффициента поглощения в агрегатах. Предположительно, нелинейная зависимость поглощения J-агрегата от его размера, может быть объяснен формированием центров поглощения на поверхности J-агрегата в виде подвижных поверхностных молекул. Был определен пороговый диапазон концентрации молекул ICG, при котором происходит переход от агрегации с увеличением размера с медленным прибавлением молекул J-агрегата ICG в высоту, но с быстрым прибавлением в ширину

МЕТОДЫ ФОТОНИКИ ДЛЯ ОЦЕНКИ КАЧЕСТВА ПРИЖИВЛЕНИЯ КОЖНЫХ ТРАНСПЛАНТАТОВ

 In this review, based on more than 70 articles of Russian and foreign authors, methods of skin engraftment monitoring are discussed. Main processes occurring in skin on cellular and subcellular levels at different stages of engraftment are considered. Optical methods which allow performing non-invasive analysis of blood vessels, collagen concentration and form of cellular respiration (by NADH fluorescence) are described. Comparative analysis of nuclear and optical methods for engraftment monitoring highly developed and widespread nowadays is presented. The advantages of optical methods includes multifunctionality, usability and clarity of results, safety and low cost. In contrast to X-ray CT, MRI and ultrasound, optical methods can be used in monitoring mode. One of the promising directions for improving quality of engraftment due to antibacterial effect, photodynamic therapy, is described in details. The use of crystalline organic nanophotosensitizers (particularly aluminum phthalocyanine) is shown to be the most promising. The main distinctive feature of its application is that nanoparticles injected into wound surface or contact area of tissue graft are not photoactive until the moment the inflammation starts. The development of method for assessing skin condition by spectroscopic properties of tissue components (using fluorescent dyes and photosensitizers in molecular and nanoforms), which allows analyzing physiological state of skin (degree and rate of engraftment or rejection) and controlling certain biochemical and physiological parameters of a tissue graft or an entire area of affected skin is shown to be crucial.Настоящий обзор, основанный более чем на 70 проанализированных статьях российских и зарубежных авторов, посвящен методам мониторинга состояния трансплантируемых участков кожи. В обзоре рассмотрены основные процессы, происходящие в коже на клеточном и субклеточном уровнях на разных этапах приживления трансплантата. Описаны оптические методы, позволяющие проводить неинвазивный анализ состояния кровеносных сосудов, концентрации коллагена, типа клеточного дыхания (по флуоресценции NADH). Приведена сравнительная таблица ядерных и оптических методов мониторинга состояния приживления трансплантата, наиболее широко развитых и использующихся на сегодняшний день. Отмечено, что преимущество оптических методов заключается в многофункциональности, простоте использования и интерпретации результатов, безопасности, низкой стоимости, а также в возможности использования в режиме мониторинга, в отличие от рентгено-компьютерной томографии, МРТ и УЗИ. Подробно рассмотрено одно из перспективных направлений, используемых для улучшения качества приживления трансплантатов преимущественно за счет антимикробного эффекта – фотодинамическая терапия. Отмечено, что перспективным является использование для фотодинамической терапии кристаллических наночастиц органических фотосенсибилизаторов, в частности фталоцианина алюминия. Основная отличительная особенность их использования заключается в том, что наночастицы, введенные в область раневой поверхности или в контактную область приживляемой ткани или трансплантата, не проявляют фотоактивности до момента начала воспаления. Сделан вывод, что актуальной является задача по разработке метода оценки состояния кожного покрова по спектроскопическим свойствам компонентов тканей (с использованием флуоресцентных красителей и фотосенсибилизаторов в молекулярной и наноформах), который позволит анализировать физиологическое состояние кожного покрова (степень и скорость приживления или отторжения), а также контролировать некоторые биохимические и физиологические параметры трансплантата или всей области поражения кожи

Complex-formation properties of orginal and generic fluoroquinolon drugs with respect to magnesium ions dependent of dissolution pH

The article deals with the influence of the dissolution medium’s pH value on the complexing properties of generic fluoroquinolones with respect to magnesium ions in vitro.В статье рассмотрено влияние значения pH среды растворения на комплексообразующие свойства воспроизведённых препаратов фторхинолонов по отношению к ионам магния in vitro

Modeling factors of environmental tourism development in innovation economy

© Foundation Environmental Protection & Research-FEPR. The factors’ modeling of ecological tourism development in innovative economy is carried out in the article. The relevance of the article is due to the fact that the issues of the services industry’s development, especially in the field of ecological tourism, have not yet been fully resolved and require additional study and systematization of the factors determining them, which is especially important in the conditions of formation and development of the service economy in Russia. The purpose of the article is to systematize the factors of ecological tourism sector development from the position of cluster development of territories and evaluation of entrepreneurial potential in this area. The main research methods used in the article are description, comparison, generalization, analysis and synthesis, descriptive and cluster analysis. The clustering of Russia’s regions in five groups with similar socio-economic characteristics was carried out on the basis of cluster analysis in terms of paid services’ volume in the ecotourism market, real incomes of the population, per capita income of the population, profitability of goods sold in the industrial sector, innovative activity of organizations. The article systematizes the data of organizations’ business activity in the sphere of services in the field of ecological tourism, identifies the key drivers and inhibitors of entrepreneur confidence of business entities in the sector of the economy specializing in the provision of services in the field of ecological tourism. The materials of the article can be used in the development of measures to improve the efficiency of the service sector of the economy and eco-tourism, taking into account socio-economic trends in the innovation economy

Management of the finances of households in conditions of sustainable development

To successfully implement a sustainable development in Russia, it becomes crucial to form a culture of personal finance management in civil society that is impossible without developing the investment potential of households and increasing the overall level of financial literacy. The need for sustainable development and the advancement of society is determined by the activity of civil society in this direction. The key role of households in solving the long-term sustainable development problems is determined by the state's concern with the solution of pressing problems, especially in the crisis conditions. This determines the decisive role of the improvement and development of civil society structures, which includes public organizations, mass movements, public policy institutions and expert institutions of sustainable development. The possibility of active participation of all sectors of society, including government, business and civil society, stands on the path to success of progress towards sustainable development, solving social and economic problems on the basis of ensuring "green" production and consumption. The research materials are of practical importance, since they consider citizens' money as an investment resource for the introduction of green economy and the concept of sustainable development, and can be applied as a diversification and rationalization of personal finance management

Integrated management of flows in petroleum products supply chains in the field of hydrocarbons deep processing

© 2016, Econjournals. All rights reserved.The urgency of the problems stated in the article is reasoned by the fact that the requirements on the supply chain management system in the petrochemical industry become high on the basis of an integrated logistics concept. The purpose of the article is to develop methods to systematize the advantages of an integrated model of the petroleum products’ supply chain. The leading approach to the study of this problem is the modeling method that allows assessing of the effectiveness of petroleum products’ integrated supply chains. The article presents an analytical review of petroleum products’ market development in the Tatarstan Republic. The content of integrated control of flows in the supply chain of petroleum products in the field of hydrocarbons’ deep processing is disclosed. The submissions of the article have theoretical and practical significance for the development of models of the integrated supply chains management in the petrochemical industry

Integrated management of flows in petroleum products supply chains in the field of hydrocarbons deep processing

© 2016, Econjournals. All rights reserved.The urgency of the problems stated in the article is reasoned by the fact that the requirements on the supply chain management system in the petrochemical industry become high on the basis of an integrated logistics concept. The purpose of the article is to develop methods to systematize the advantages of an integrated model of the petroleum products’ supply chain. The leading approach to the study of this problem is the modeling method that allows assessing of the effectiveness of petroleum products’ integrated supply chains. The article presents an analytical review of petroleum products’ market development in the Tatarstan Republic. The content of integrated control of flows in the supply chain of petroleum products in the field of hydrocarbons’ deep processing is disclosed. The submissions of the article have theoretical and practical significance for the development of models of the integrated supply chains management in the petrochemical industry