Caffeine, Energy Drinks and Atrial Fibrillation: A Mini-Review

The present mini-review analyzes the relationship between caffeine and atrial fibrillation (AF) and specifically referred to the association between energy drinks (EDs) and occurrence of AF. The topic is very actual whereas data in literature are controversial. The quantity of caffeine in EDs is really high and is often underestimated by users. Several case-reports suggested a risk of AF in subjects assuming high quantity of EDs and it is becoming a social problem due to the wide use of mix drinks (EDs and alcohol) among youth

Eye Tracking Impact on Quality-of-Life of ALS Patients

Chronic neurological disorders in their advanced phase are characterized by a progressive loss of mobility (use of upper and lower limbs), speech and social life. Some of these pathologies, such as amyotrophic lateral sclerosis and multiple sclerosis, are paradigmatic of these deficits. High technology communication instruments, such as eye tracking, can be an extremely important possibility to reintroduce these patients in their family and social life, in particular when they suffer severe disability. This paper reports and describes the results of an ongoing experimentation about Eye Tracking impact on the quality of life of amyotrophic lateral sclerosis patients. The aim of the experimentation is to evaluate if and when eye tracking technologies have a positive impact on patients' live

The association between tumor-infiltrating lymphocytes (TILs) and metastatic course in neuroendocrine neoplasms.

A moderate lymphocytic infiltration was found in about 25% of these well-differentiated neoplasms, all of which had no distant metastases to liver or pulmonary hilar lymph nodes during a follow-up period >10 years; mild or absent lymphocytic infiltrates have been observed in those cases with metastatic spread, discovered synchronously or after follow-up of 10 years (P < .05)

Gender differences in adherence to mediterranean diet and risk of atrial fibrillation

Adherence to the Mediterranean Diet i associated with a reduction of overall mortality and mortality from cardiovascular disease and cancer

Education in anesthesia: three years of online logbook implementation in an Italian school

BACKGROUND: The progress of physicians through residency training in anesthesiology can be monitored using an online logbook. The aim of this investigation was to establish how residents record clinical activities in their computerized web-based logbooks during their first years of anesthesiology training. METHODS: For this retrospective observational trial, the ESSE 3(©) digital registry of the University of Modena and Reggio Emilia, Italy was used to record all anesthesia-related activities performed by three consecutive year-groups of residents (Groups A, B and C) between 2009 and 2012. The ratio of activities to sessions was chosen as a surrogate measure of compliance. RESULTS: A total of 41,348 actions were analyzed. The ratio of activities to sessions showed a statistically significant decline for all activities concerning the perioperative management of anesthesia, with a steady reduction from the first to the last year-group (Group A 23.7, Group B 14.1 and Group C 2.2; p = 0.003). CONCLUSIONS: An online activities logbook is a useful tool for recording and assessing the clinical activities undertaken by each resident during residency training in anesthesiology

Dhea as marker of good surgical homeostasis

The serum DHEA concentration can represent a valuable indicator of an "equilibrated" metabolic condition

Radiotherapy-induced mesorectum alterations: histological evaluation of 90 consecutive cases.

Abstract Objective. In order to identify the radiotherapy-induced histological modifications in the mesorectum, we reviewed the surgical specimens of 90 rectal resections comprehensive of the total mesorectal excision (23 cases radiologically classified as cT2N0M0 and 67 as cT3N0M0). All patients were preoperative treated with radiotherapy: 20 with 50 Gy, 20 with 20 Gy and 50 Gy irradiation associated to FOLFOX scheme chemotherapy. Material and methods. Routine hematoxylin and eosin stained serial slides at 5 mm of intervals were obtained from surgical specimens and included the tumor site and the adjacent irradiated mucosa, the submucosa and the muscular layers of the rectal wall and the mesorectal adipose tissue, completely removed until to the mesorectal fascia. Ten subjects (eight cT2N0M0 and two cT3N0M0), who did not received preoperative oncological treatments were adopted as controls. Results. Histologically, examination revealed fibrosis of the adipose tissue in 86 cases (95%), vascular damage including vasculities and fibrotic thickening wall of arteries and veins in 46 cases (51%), sclero-hyalinosis of lymph nodes with pericapsular fibrosis in 22 cases (23%) and perineural deposition of fibrosis in 12 (13%). These findings were ubiquitously observed in the whole mesorectum. Fibrosis of the adipose tissue and vasculitis were mainly associated to the combination of 50 Gy radiations plus chemotherapy (p < 0.05). Conclusion. The detection of histopathological alterations in the mesorectum can give reason of the well-known postoperative complications and long-term sequels