6 research outputs found
Eventos de supercontagio.
Los eventos de supercontagio, aquellos donde se produce una transmisiĂłn de la enfermedad a un nĂşmero de personas mucho mayor al promedio para esa misma enfermedad, presentan un riesgo importante para el manejo de la pandemia de COVID-19 en los prĂłximos meses. En esta nota intentamos avanzar en la caracterizaciĂłn, a partir de un repaso de la literatura existente, de los eventos de supercontagio, entender su relevancia en el marco de la COVID-19, y presentar algunas posibles acciones que, a travĂ©s del control de este tipo de eventos, podrĂan ser Ăştiles para el manejo general de la pandemia, en especial en el caso de Uruguay
Selection signatures in ancestral populations.
<p>SNP with significant FLK value at the 5% FDR level, with estimated allele frequencies in all ancestral groups. The number of genes included in each region (1Mb up-or-downstream the position) and the rank of candidate genes within the region is also provided. : signatures of selection previously identified <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0103813#pone.0103813-Kijas2" target="_blank">[4]</a>.</p
Selection signatures in the 7 geographical groups.
<p>Regions identified with the hapFLK or FLK test, with the corresponding population group and most differentiated populations (except for the AFR group). Full names of groups and populations are given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0103813#pone-0103813-t001" target="_blank">Table 1</a>. The number of genes included in each region and the rank of candidate genes within the region is also provided. Overlapping regions detected in different population groups or with different tests are grouped within horizontal lines (in this case candidate genes are the same for all overlapping regions and are only reported in the first one). : signatures of selection previously identified <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0103813#pone.0103813-Kijas2" target="_blank">[4]</a>. : this outlying region is not due to evolutionary processes (see details in the main text).</p
Localization of selection signatures identified in 7 groups of populations.
<p>Candidate genes are indicated above their genomic localization. Only chromosomes harboring selection signatures are plotted.</p