Ouro, porcos, escravos e café: as origens das fortunas oitocentistas em São Pedro de Cantagalo, Rio de Janeiro (últimas décadas do século XVIII e primeiras do XIX)

The municipality of Cantagalo in the state of Rio de Janeiro is historically linked to gold exploration, the breading of pigs and to the production of food for the domestic market and of coffee by slaves for export markets. I will analyze the construction of the material daily life of the region “Novas Minas dos Sertões de Macacu” or “Cantagalo”, as it was named at the end of the eighteenth century. Later, it became known as the city of São Pedro de Cantagalo, in 1814, it retained this name through the last decades of the eighteenth century and the first decades of the nineteenth century. The documental basis used are post-mortem inventories, official correspondence exchanged between colonial and metropolitan authorities, parochial records of baptism, marriage and death and newspaper articles of the Rio de Janeiro press.O município de Cantagalo, no estado do Rio de Janeiro, tem sua história ligada à exploração de ouro, criação de porcos e produção de alimentos para o mercado interno, e à cafeicultura escravista e mercantil exportadora. Analiso a construção do cotidiano material da região das “Novas Minas dos Sertões de Macacu” ou de “Cantagalo”, como foi denominada no fim do século XVIII, e vila de São Pedro de Cantagalo em 1814, entre as últimas décadas do século XVIII e as primeiras do XIX. Utilizo como base documental inventários post-mortem, correspondência oficial trocada entre autoridades coloniais e metropolitanas, registros paroquiais de batizados, casamentos e óbitos e artigos de periódicos da imprensa do Rio de Janeiro

Fontes textuais e vida material: observações preliminares sobre casas de moradia nos Campos dos Goitacases, sécs. XVIII e XIX

The author explores a rich collection of 18th.-19th-century inventories regarding inhabitants from CamPos dos Goitacazes (the area nowadays known as "Norte Fluminense", State of Rio de Janeiro, Brazil). Inferences are made on several subjects, including morphological and technological attributes of the structures, patterns of activities (particularly the productive onesL spatial ensembles, artifact systems, relationships with family organization, servile condition, valorative systems etc. Observable changes are registered.A autora explora uma rica coleção de inventários dos séculos XVIII e XIX, referentes a habitantes dos Campos de Goitacazes (no atual Norte Fluminense, RJ). São propostas inferências sobre vários tópicos: atributos morfológicos e tecnológicos das estruturas, padrões de atividades (em particular as f:!rodutivas), arranjos espaciais, sistemas de artefatos, relações com a organização familiar, a condição servil, sistemas de valor, etc. Também se registram as mudanças observadas

Fontes textuais e vida material: observações preliminares sobre casas de moradia nos Campos dos Goitacases, sécs. XVIII e XIX

A autora explora uma rica coleção de inventários dos séculos XVIII e XIX, referentes a habitantes dos Campos de Goitacazes (no atual Norte Fluminense, RJ). São propostas inferências sobre vários tópicos: atributos morfológicos e tecnológicos das estruturas, padrões de atividades (em particular as f:!rodutivas), arranjos espaciais, sistemas de artefatos, relações com a organização familiar, a condição servil, sistemas de valor, etc. Também se registram as mudanças observadas

Strengthening therapeutic adherence and pharmacovigilance to antimalarial treatment in Manaus, Brazil: a multicomponent strategy using mHealth

Background: Public health initiatives for improving adherence to primaquine based regimens and enhancing effective pharmacovigilance are needed to support the efforts for malaria elimination in real world conditions. Methods: A multicomponent patient-oriented strategy using a Smart Safety Surveillance (3S) approach including: (1) educational materials for treatment counselling and identification of warning symptoms of haemolytic anaemia; (2) an mHealth component using Short Message Service (SMS) treatment reminders and (3) development and implementation of follow-up phone surveys three days after treatment completion, using a web-based platform linked to the local information system of malaria. Adherence was measured using the Morisky Medication Adherence Scale. Self-reported events were registered using a structured questionnaire and communicated to the Brazilian Health Regulatory Agency. Results: Educational materials were disseminated to 5594 patients, of whom 1512 voluntarily entered the mHealth component through the local information system; 7323 SMS were sent, and 1062 participants completed a follow-up survey after treatment. The mean age of patients was 37.36 years (SD 13.65), 61.24% were male, 98.54% were infected with. Plasmodium vivax and 95.90% received a short regimen of chloroquine plus primaquine (CQ + PQ 7 days), as per malaria case management guidelines in Brazil. From the 1062 surveyed participants 93.31% were considered adherent to the treatment. Most of the patients (95.20%) reported at least one adverse event. Headache, lack of appetite and nausea/vomiting were the most frequently reported adverse events by 77.31%, 70.90% and 56.78% of the patients respectively. A quarter of the patients reported anxiety or depression symptoms; 57 (5.37%) patients reported 5 to 6 warning symptoms of haemolytic anaemia including jaundice and dark urine in 44 (4.14%). Overall, three patients presenting symptoms of haemolytic anaemia attended a hospital and were diagnosed with G6PD deficiency, and one had haemolysis. All of them recovered. Conclusions: Under real world conditions, a multicomponent patient-oriented strategy using information and communication technologies allowed health care providers to reinforce treatment adherence and enhance safety surveillance of adverse events associated with regimens using primaquine. Active monitoring through phone surveys also reduced under-reporting of ADRs. This approach is low-cost, scalable and able to support prioritized activities of the national malaria programme.Fil: Macías Saint Gerons, Diego. Universidad de Valencia; EspañaFil: Rodovalho, Sheila. Universidad Federal del Amazonas.; BrasilFil: Barros Dias, Ádila Liliane. Universidad Federal del Amazonas.; BrasilFil: Lacerda Ulysses de Carvalho, André. Pan American Health Organization; BrasilFil: Beratarrechea, Andrea Gabriela. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Monteiro, Wuelton Marcelo. Universidad Federal del Amazonas.; BrasilFil: Barata Machado, Myrna. State of Amazonas Health Surveillance Foundation; BrasilFil: Fernandes da Costa, Cristiano. State of Amazonas Health Surveillance Foundation; BrasilFil: Yoshito Wada, Marcelo. No especifíca;Fil: Maximiano Faria de Almeida, Márcia Helena. No especifíca;Fil: Silva de Matos Fonseca, Rayanne. Fundação de Medicina Tropical Dr. Heitor Vieira Dourado; BrasilFil: Mota Cordeiro, Jady Shayenne. Fundação de Medicina Tropical Dr. Heitor Vieira Dourado; BrasilFil: Rodrigues Antolini, Alinne Paula. No especifíca;Fil: Nepomuceno, João Altecir. No especifíca;Fil: Fleck, Karen. Brazilian Health Regulatory Agency; BrasilFil: Simioni Gasparotto, Fernanda. Brazilian Health Regulatory Agency; BrasilFil: Lacerda, Marcus. Fundação de Medicina Tropical Dr. Heitor Vieira Dourado; BrasilFil: Rojas Cortés, Robin. Pan American Health Organization; Estados UnidosFil: Pal, Shanthi Narayan. No especifíca;Fil: Porrás, Analía I.. Pan American Health Organization; Estados UnidosFil: Ade, María de la Paz. Pan American Health Organization; Estados UnidosFil: Castro, José Luis. Pan American Health Organization; Estados Unido