Caracterização química e físico-química de novos híbridos de Maracujá Amarelo.

O maracujá pertence à ordem Passiflorales, família Passifloraceae, gênero Passiflora. No Brasil, existem cerca de 150 espécies nativas de maracujá. As espécies mais cultivadas no Brasil e no mundo são os maracujás amarelo (Passiflora edulis Sims f. flavicarpa Deg.), roxo (P. edulis f. edulis Sims), e doce (Passiflora alata Curtis), sendo a última de grande ocorrência silvestre no Brasil (Junqueira, 2006)

Effects of Cement Bases on the Stresses in Amalgam Restorations

A computerized dental model was used to study the stress induced in a Class 1 amalgam restoration when supported by bases of varying materials and thicknesses. Under the same load, the maximum tensile stresses and deftections in the amalgam restoration increased at least threefold with a zinc oxideeugenol base as compared with a ZnPO 4 cement base.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67330/2/10.1177_00220345750540010101.pd

Stress distribution within circumferential clasp arms

An analysis of stress distributions within circumferential clasp arms with various tapers, was undertaken in an effort to (1) determine the area of maximum stress concentration in both tapered and non-tapered clasps, and (2) to compare this point of maximum stress concentration with the area of frequent clasp breakage. The non-tapered clasp showed better distribution of stresses than the tapered clasps. The less favourable stress concentrations could result in eventual failure of the clasp when coupled with other factors such as porosities. The maximum shear stresses in the non-tapered clasp also were lower than those in the tapered clasps. As the taper of the clasp became more accentuated, the magnitude of the stresses increased and shifted towards the tip of the clasp. The maximum tensile stress calculated in a replica of a chromium–cobalt–nickel clasp was in the order of 34 MN/m 2 which is well below the ultimate tensile strength of the alloy. This observation leads to the proposal that failure of clasps is a function not only of design but also of other variables, such as porosities, surface irregularities, and fatigue.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/71998/1/j.1365-2842.1976.tb01453.x.pd

Anthropometric characteristics, quality of life and functional capacity in adults living with HIV in Puerto Rico

Survival and longevity rates in people living with HIV (HIV+) have increased with the availability and use of antiretroviral therapy (ART). However, despite the above HIV+ adults treated with ART have a higher risk of developing dyslipidemia and high waist circumference. In addition, they have lower cardiorespiratory fitness, loss of muscle mass, reduced balance, and reduced functional capacity, which affects their quality of life. To explore the impact of balance perception, treadmill time, grip strength, body mass index (BMI), and waist-to-height ratio (WHtR) on quality of life in Latino Hispanic people living with HIV. This study recruited twenty-five participants from a community-based center, La Perla de Gran Precio, in San Juan, Puerto Rico, with the medical diagnosis of HIV. Descriptive measures were obtained for all variables of interest, and correlation and regression analyses were used to assess the associations between functional capacity, quality of life, and anthropometric measures. Result: Men had greater left- and right-hand grip strength than women (86.9±18.8, 56.9±26.8 kg; p=0.003 and 87.6±15.1 vs. 61.4±26.6 kg; p =0.004). Two anthropometric variables showed a trend toward a moderate positive correlation with quality of life:  WHtR (r= -0.38, p =0.12) and BMI (r= -0.38, p = p-0.14). Although gender differences in upper body strength are expected, handgrip strength is within the gender-specific average range of the general population. The integration of anthropometric characteristics and upper body strength when prescribing exercise must be considered since these factors influence functional capacity and quality of life among HIV+ adults

The effect of instant arabica coffee on the viability of lactobacillus acidophilus and bifidobacterium bifidum in a probiotic, lacto-free dessert.

O objetivo deste estudo foi avaliar a viabilidade de bactérias probióticas Bifidobacterium bifidum subsp. lactis e Lactobacillus acidophilus em uma sobremesa sem lactose, à base de extrato de soja, com diferentes concentrações de café (0 a 1,5%), armazenada a 7 [graus] C. Quatro formulações produzidas foram avaliadas quanto ao pH, acidez e contagem das bactérias probióticas após 0, 7, 14 e 21 dias de armazenamento. Nem o tempo, nem o teor de café influenciaram significativamente o teor de ácido lático e o pH das amostras estudadas. De acordo com a ANVISA, para que o produto possa ser considerado probiótico, a contagem total de cada cepa por porção (100g) deve ser igual ou superior a 10 [elevado a 8]. No presente estudo, este valor foi observado para L.acidophilus até 21 dias, e para B.bifidum até 7 dias de armazenamento, ambos sem interferência do teor ou percentual de café.Food: the tree that sustains life. 1636

Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes.

Serine/threonine protein phosphatase 5 (PP5) is ubiquitously expressed in eukaryotic cells; however, its function in cardiomyocytes is unknown. Under basal conditions, PP5 is autoinhibited, but enzymatic activity rises upon binding of specific factors, such as the chaperone Hsp90. Here we show that PP5 binds and dephosphorylates the elastic N2B-unique sequence (N2Bus) of titin in cardiomyocytes. Using various binding and phosphorylation tests, cell-culture manipulation, and transgenic mouse hearts, we demonstrate that PP5 associates with N2Bus in vitro and in sarcomeres and is antagonistic to several protein kinases, which phosphorylate N2Bus and lower titin-based passive tension. PP5 is pathologically elevated and likely contributes to hypo-phosphorylation of N2Bus in failing human hearts. Furthermore, Hsp90-activated PP5 interacts with components of a sarcomeric, N2Bus-associated, mechanosensor complex, and blocks mitogen-activated protein-kinase signaling in this complex. Our work establishes PP5 as a compartmentalized, well-controlled phosphatase in cardiomyocytes, which regulates titin properties and kinase signaling at the myofilaments