A LITERATURE ANALYSIS ON 14 CASES OF ALLERGIC SHOCK CAUSED BY SAFFLOWER INJECTION

The objective of this paper was to investigate the characteristics and general rules of domestic safflower injection causing allergic shock, to retrieve the medical journals published domestically, and to make statistical analysis on the cases of allergic shock caused by safflower injection. Results showed that the incidence of allergic shock caused by safflower injection in patients above 40 years old was high: females were more than males. It occurred within 30min after medication, and no patient died after emergency treatment. The study concluded that allergic shock caused by safflower injection is related to many factors, and clinical care personnel should pay more attention to it

High-performance and Scalable Software-based NVMe Virtualization Mechanism with I/O Queues Passthrough

NVMe(Non-Volatile Memory Express) is an industry standard for solid-state drives (SSDs) that has been widely adopted in data centers. NVMe virtualization is crucial in cloud computing as it allows for virtualized NVMe devices to be used by virtual machines (VMs), thereby improving the utilization of storage resources. However, traditional software-based solutions have flexibility benefits but often come at the cost of performance degradation or high CPU overhead. On the other hand, hardware-assisted solutions offer high performance and low CPU usage, but their adoption is often limited by the need for special hardware support or the requirement for new hardware development. In this paper, we propose LightIOV, a novel software-based NVMe virtualization mechanism that achieves high performance and scalability without consuming valuable CPU resources and without requiring special hardware support. LightIOV can support thousands of VMs on each server. The key idea behind LightIOV is NVMe hardware I/O queues passthrough, which enables VMs to directly access I/O queues of NVMe devices, thus eliminating virtualization overhead and providing near-native performance. Results from our experiments show that LightIOV can provide comparable performance to VFIO, with an IOPS of 97.6%-100.2% of VFIO. Furthermore, in high-density VMs environments, LightIOV achieves 31.4% lower latency than SPDK-Vhost when running 200 VMs, and an improvement of 27.1% in OPS performance in real-world applications

Effects of single session transcranial direct current stimulation on aerobic performance and one arm pull-down explosive force of professional rock climbers

Objective: To explore the effects of single-session transcranial direct current stimulation (tDCS) on aerobic performance and explosive force in the one-arm pull-down of long-term trained rock climbers.Method: Twenty athletes (twelve male and eight female) from the Rock Climbing Team of Hunan province (Hunan, China) were selected for a randomized double-blind crossover study. After baseline tests, All subjects visited laboratories twice to randomly receive either sham or a-tDCS at a current intensity of 2 mA for 20 min. The two visits were more than 72 h apart. Immediately after each stimulation, subjects completed a 9-min 3-level-load aerobic test and a one-arm pull-down test.Results: Differences in the heart rate immediately after 9-min incremental aerobic exercises revealed no statistical significance between each group (p > 0.05). However, the decrease in heart rate per unit time after exercise after real stimulation was significantly better than before stimulation (p < 0.05), and no statistical significance was observed between after sham stimulation and before stimulation (p > 0.05). One-arm pull-down explosive force on both sides after real stimulation was improved by a-tDCS compared with before stimulation, but with no significant difference (p > 0.05). Real stimulation was significantly improved, compared with sham stimulation on the right side (p < 0.05).Conclusion: Single-session tDCS could potentially benefit sports performance in professional athletes

Hemodynamic Characteristics Associated With Paraclinoid Aneurysm Recurrence in Patients After Embolization

Objective: To investigate the hemodynamic features before and after embolization of paraclinoidal aneurysms using hemodynamic numerical simulation and the influence of embolization on recurrence after embolization.Methods: From January 2016 to December 2017, we enrolled a total of 113 paraclinoidal aneurysms treated with embolization. They were divided into recurrent group and stable group depending on follow-up results. An aneurysm model was generated based on 3D-DSA before and after embolization. The hemodynamic characteristics were analyzed between two groups using Computational fluid dynamic (CFD).Results: In the recurrent group, the peak systolic WSS, OSI and velocity around the aneurysm neck areas prior to embolization were 20.47 ± 3.04 Pa, 0.06 ± 0.02 and 0.07 ± 0.03 m/s, respectively. These values were 23.50 ± 4.11 Pa, 0.06 ± 0.01 and 0.11 ± 0.02 m/s, respectively in the stable group (P > 0.05). The WSS, OSI, velocity around the same areas in the recurrent group after embolization were 35.59 ± 8.75 Pa, 0.07 ± 0.02 and 0.12 ± 0.03 m/s, respectively (P < 0.01). In the stable group, the WSS, OSI and velocity were 13.08 ± 2.89 Pa, 0.04 ± 0.01 and 0.07 ± 0.02 m/s, respectively (P < 0.01). After embolization, the WSS, OSI and velocity around the aneurysm neck areas in the recurrent group were significantly higher than those in the stable group.Conclusions: High peak systolic WSS, OSI and velocity around aneurysm neck areas after embolization of paraclinoidal aneurysms may be important factors leading to recurrence

Clinical application of Kirschner wires combined with 5-Ethibond fixation for patella fractures

BackgroundPatella fractures that require surgery are conventionally treated using Kirschner wires (K-wires) and stainless steel wires. In recent years, the nonabsorbable polyester has been reported to have excellent outcomes clinically. Therefore, the goal of our study was to evaluate the effects of Kirschner wires combined with 5-Ethibond on treating patellar fractures.MethodsFrom July 2018 to January 2022, 22 patella fracture patients were treated with Kirschner wires combined with 5-Ethibond. Radiographs of the knees were used to evaluate fracture healing and hardware complications. The clinical results were evaluated through the functional score, knee joint range of motion (ROM), and Bostman patella fracture functional score.ResultsThe average age of patients was 57.4 ± 11.9 (range 33–74) years. The mean follow-up time was 15.2 ± 7.6 (range 4–36) months. The mean operation time was 56.8 ± 8.7 (range 45–80) min. The entire patients had bony union at an average of 10.5 ± 1.9 (range 8–14) weeks. At the final follow-up, the mean range of postoperative ROM was 123.4° ± 14.6° (range 95°–140°), and the functional score was 28.7 ± 1.2 (range 26–30) points. No patient exhibited internal fixation failure, and no symptomatic implants or skin complications were recorded.ConclusionsThe fixation approach using K-wires combined with 5-Ethibond has a lower complication rate and delivers superior clinical results. This research reveals that such technology is a safe and prospective substitute for conventional metal fixation approaches

Assessment of Cardiovascular Health of Children Ages 6 to 10 Years Conceived by Assisted Reproductive Technology

Importance: Assisted reproductive technology (ART) has been widely used for treatment of infertility and has brought millions of births worldwide. The health of offspring conceived by ART has been of much concern, and adverse cardiovascular health outcomes have been reported by previous studies.Objective: To assess the cardiovascular health of children conceived by ART.Design, setting, and participants: This cohort study was conducted among participants recruited from November 2017 to February 2019. Participants were 382 children conceived by ART who were selected from a single reproductive center and 382 children who were naturally conceived, randomly selected from a primary school, and matched by sex, age, and maternal age at the child's birth (2 years older or younger). Data were analyzed from March 2019 through December 2019.Exposures: Conception by ART.Main outcomes and measures: Blood pressure was measured, and echocardiography was performed to determine left ventricular structural and functional parameters. Adjusted relative wall thickness (aRWT) was found for age, with high RWT defined as an aRWT of 0.375 or more.Results: Among 764 children aged 6 to 10 years, 382 children were conceived by ART (mean [SD] age, 7.20 [1.21] years; 201 [52.6%] boys) and 382 children were naturally conceived (mean [SD] age, 7.20 [1.21] years; 201 [52.6%] boys). Children conceived by ART had statistically significantly increased mean (SD) height (130.2 [9.5] cm vs 128.5 [8.1] cm; P = .007) and body mass index (17.6 [3.6] vs 17.1 [2.7]; P = .03). Those conceived by ART, compared with children in the matched control group, had statistically significantly increased blood pressure (mean [SD] systolic blood pressure, 105.5 [6.9] mm Hg vs 103.5 [8.4] mm Hg; adjusted P P P P 2.7 vs 28.28 [3.54] g/m2.7; adjusted P P P = .03), high RWT (61 children [16.0%] vs 0 children; P P for left ventricle remodeling Conclusions and relevance: This study found that children conceived by ART had increased blood pressure and unfavorable changes in left ventricular structure and function compared with children who were naturally conceived. These findings suggest that further studies are needed to investigate the potential mechanisms and long-term outcomes associated with these differences.</p