Relationship of food insecurity to women's dietary outcomes: a systematic review

Context: Food insecurity matters for women's nutrition and health. Objective: This review sought to comprehensively evaluate how food insecurity relates to a full range of dietary outcomes (food groups, total energy, macronutrients, micronutrients, and overall dietary quality) among adult women living in Canada and the United States. Data sources: Peer-reviewed databases (PubMed/MEDLINE, CINAHL, Scopus, Web of Science) and gray literature sources from 1995 to 2016 were searched. Data extraction: Observational studies were used to calculate a percentage difference in dietary intake for food-insecure and food-secure groups. Results: Of the 24 included studies, the majority found food-insecure women had lower food group frequencies (dairy, total fruits and vegetables, total grains, and meats/meat alternatives) and intakes of macro- and micronutrients relative to food-secure women. Methodological quality varied. Among high-quality studies, food insecurity was negatively associated with dairy, fruits and vegetables, grains, meats/meats alternatives, protein, total fat, calcium, iron, magnesium, vitamins A and C, and folate. Conclusions: Results hold practical relevance for selecting nutritional targets in programs, particularly for nutrient-rich foods with iron and folate, which are more important for women's health

Trees over Infinite Structures and Path Logics with Synchronization

We provide decidability and undecidability results on the model-checking problem for infinite tree structures. These tree structures are built from sequences of elements of infinite relational structures. More precisely, we deal with the tree iteration of a relational structure M in the sense of Shelah-Stupp. In contrast to classical results where model-checking is shown decidable for MSO-logic, we show decidability of the tree model-checking problem for logics that allow only path quantifiers and chain quantifiers (where chains are subsets of paths), as they appear in branching time logics; however, at the same time the tree is enriched by the equal-level relation (which holds between vertices u, v if they are on the same tree level). We separate cleanly the tree logic from the logic used for expressing properties of the underlying structure M. We illustrate the scope of the decidability results by showing that two slight extensions of the framework lead to undecidability. In particular, this applies to the (stronger) tree iteration in the sense of Muchnik-Walukiewicz.Comment: In Proceedings INFINITY 2011, arXiv:1111.267

Solidification behavior of intensively sheared hypoeutectic Al-Si alloy liquid

The official published version of this article can be found at the link below.The effect of the processing temperature on the microstructural and mechanical properties of Al-Si (hypoeutectic) alloy solidified from intensively sheared liquid metal has been investigated systematically. Intensive shearing gives a significant refinement in grain size and intermetallic particle size. It also is observed that the morphology of intermetallics, defect bands, and microscopic defects in high-pressure die cast components are affected by intensive shearing the liquid metal. We attempt to discuss the possible mechanism for these effects.Funded by the EPSRC

The Dynamics of the India‐Eurasia Collision: Faulted Viscous Continuum Models Constrained by High‐Resolution Sentinel‐1 InSAR and GNSS Velocities

The distribution and magnitude of forces driving lithospheric deformation in the India-Eurasia collision zone have been debated over many decades. Here we test a two-dimensional (2-D) Thin Viscous Shell approach that has been adapted to explicitly account for displacement on major faults and investigate the impact of lateral variations in depth-averaged lithospheric strength. We present a suite of dynamic models to explain the key features from new high-resolution Sentinel-1 Interferometric Synthetic Aperture Radar as well as Global Navigation Satellite System velocities. Comparisons between calculated and geodetically observed velocity and strain rate fields indicate: (a) internal buoyancy forces from Gravitational Potential Energy acting on a relatively weak region of highest topography (>2,000 m) contribute to dilatation of the high plateau and contraction on the margins; (b) a weak central Tibetan Plateau (∼10²¹ Pa s compared to far-field depth-averaged effective viscosity of at least 10²²–10²³ Pa s) is required to explain the observed long-wavelength eastward velocity variation; (c) localized displacement on fault systems enables strain concentration and clockwise rotation around the Eastern Himalayan Syntaxis. We discuss the tectonic implications for rheology of the lithosphere, distribution of geodetic strain, and partitioning of active faulting and seismicity

Langevin Simulation of Thermally Activated Magnetization Reversal in Nanoscale Pillars

Numerical solutions of the Landau-Lifshitz-Gilbert micromagnetic model incorporating thermal fluctuations and dipole-dipole interactions (calculated by the Fast Multipole Method) are presented for systems composed of nanoscale iron pillars of dimension 9 nm x 9 nm x 150 nm. Hysteresis loops generated under sinusoidally varying fields are obtained, while the coercive field is estimated to be 1979 $\pm$ 14 Oe using linear field sweeps at T=0 K. Thermal effects are essential to the relaxation of magnetization trapped in a metastable orientation, such as happens after a rapid reversal of an external magnetic field less than the coercive value. The distribution of switching times is compared to a simple analytic theory that describes reversal with nucleation at the ends of the nanomagnets. Results are also presented for arrays of nanomagnets oriented perpendicular to a flat substrate. Even at a separation of 300 nm, where the field from neighboring pillars is only $\sim$ 1 Oe, the interactions have a significant effect on the switching of the magnets.Comment: 19 pages RevTeX, including 12 figures, clarified discussion of numerical technique

DT/T beyond linear theory

The major contribution to the anisotropy of the temperature of the Cosmic Microwave Background (CMB) radiation is believed to come from the interaction of linear density perturbations with the radiation previous to the decoupling time. Assuming a standard thermal history for the gas after recombination, only the gravitational field produced by the linear density perturbations present on a $\Omega\neq 1$ universe can generate anisotropies at low z (these anisotropies would manifest on large angular scales). However, secondary anisotropies are inevitably produced during the nonlinear evolution of matter at late times even in a universe with a standard thermal history. Two effects associated to this nonlinear phase can give rise to new anisotropies: the time-varying gravitational potential of nonlinear structures (Rees-Sciama RS effect) and the inverse Compton scattering of the microwave photons with hot electrons in clusters of galaxies (Sunyaev-Zeldovich SZ effect). These two effects can produce distinct imprints on the CMB temperature anisotropy. We discuss the amplitude of the anisotropies expected and the relevant angular scales in different cosmological scenarios. Future sensitive experiments will be able to probe the CMB anisotropies beyong the first order primary contribution.Comment: plain tex, 16 pages, 3 figures. Proceedings of the Laredo Advance School on Astrophysics "The universe at high-z, large-scale structure and the cosmic microwave background". To be publised by Springer-Verla

Constraining the Power Spectrum using Clusters

(Shortened Abstract). We analyze a redshift sample of Abell/ACO clusters and compare them with numerical simulations based on the truncated Zel'dovich approximation (TZA), for a list of eleven dark matter (DM) models. For each model we run several realizations, on which we estimate cosmic variance effects. We analyse correlation statistics, the probability density function, and supercluster properties from percolation analysis. As a general result, we find that the distribution of galaxy clusters provides a constraint only on the shape of the power spectrum, but not on its amplitude: a shape parameter 0.18 < \Gamma < 0.25 and an effective spectral index at 20Mpc/h in the range [-1.1,-0.9] are required by the Abell/ACO data. In order to obtain complementary constraints on the spectrum amplitude, we consider the cluster abundance as estimated using the Press--Schechter approach, whose reliability is explicitly tested against N--body simulations. We conclude that, of the cosmological models considered here, the only viable models are either Cold+Hot DM ones with \Omega_\nu = [0.2-0.3], better if shared between two massive neutrinos, and flat low-density CDM models with \Omega_0 = [0.3-0.5].Comment: 37 pages, Latex file, 9 figures; New Astronomy, in pres

Identification of a RAI1-associated disease network through integration of exome sequencing, transcriptomics, and 3D genomics.

Smith-Magenis syndrome (SMS) is a developmental disability/multiple congenital anomaly disorder resulting from haploinsufficiency of RAI1. It is characterized by distinctive facial features, brachydactyly, sleep disturbances, and stereotypic behaviors. We investigated a cohort of 15 individuals with a clinical suspicion of SMS who showed neither deletion in the SMS critical region nor damaging variants in RAI1 using whole exome sequencing. A combination of network analysis (co-expression and biomedical text mining), transcriptomics, and circularized chromatin conformation capture (4C-seq) was applied to verify whether modified genes are part of the same disease network as known SMS-causing genes. Potentially deleterious variants were identified in nine of these individuals using whole-exome sequencing. Eight of these changes affect KMT2D, ZEB2, MAP2K2, GLDC, CASK, MECP2, KDM5C, and POGZ, known to be associated with Kabuki syndrome 1, Mowat-Wilson syndrome, cardiofaciocutaneous syndrome, glycine encephalopathy, mental retardation and microcephaly with pontine and cerebellar hypoplasia, X-linked mental retardation 13, X-linked mental retardation Claes-Jensen type, and White-Sutton syndrome, respectively. The ninth individual carries a de novo variant in JAKMIP1, a regulator of neuronal translation that was recently found deleted in a patient with autism spectrum disorder. Analyses of co-expression and biomedical text mining suggest that these pathologies and SMS are part of the same disease network. Further support for this hypothesis was obtained from transcriptome profiling that showed that the expression levels of both Zeb2 and Map2k2 are perturbed in Rai1 (-/-) mice. As an orthogonal approach to potentially contributory disease gene variants, we used chromatin conformation capture to reveal chromatin contacts between RAI1 and the loci flanking ZEB2 and GLDC, as well as between RAI1 and human orthologs of the genes that show perturbed expression in our Rai1 (-/-) mouse model. These holistic studies of RAI1 and its interactions allow insights into SMS and other disorders associated with intellectual disability and behavioral abnormalities. Our findings support a pan-genomic approach to the molecular diagnosis of a distinctive disorder