凍結プロセスにより誘起されるタンパク質凝集体の構造変化に関する研究

京都大学新制・課程博士博士(農学)甲第23520号農博第2467号新制||農||1086(附属図書館)学位論文||R3||N5351(農学部図書室)京都大学大学院農学研究科食品生物科学専攻(主査)教授 谷 史人, 教授 保川 清, 准教授 中川 究也学位規則第4条第1項該当Doctor of Agricultural ScienceKyoto UniversityDGA

A Neural RDE-based model for solving path-dependent PDEs

The concept of the path-dependent partial differential equation (PPDE) was first introduced in the context of path-dependent derivatives in financial markets. Its semilinear form was later identified as a non-Markovian backward stochastic differential equation (BSDE). Compared to the classical PDE, the solution of a PPDE involves an infinite-dimensional spatial variable, making it challenging to approximate, if not impossible. In this paper, we propose a neural rough differential equation (NRDE)-based model to learn PPDEs, which effectively encodes the path information through the log-signature feature while capturing the fundamental dynamics. The proposed continuous-time model for the PPDE solution offers the benefits of efficient memory usage and the ability to scale with dimensionality. Several numerical experiments, provided to validate the performance of the proposed model in comparison to the strong baseline in the literature, are used to demonstrate its effectiveness

Integrated Optimisation Model of Daily Freight Train Scheduling and Dynamic Railcar Routing Based on a Two-Layer Space-Time Network

This paper focuses on daily freight train scheduling and dynamic railcar routing problems for rail freight transportation at the operational level. Two mixed integer linear programming models that adopted different strategies were formulated based on a continuous two-layer time-space network. We simultaneously considered the benefits of railroad company and service quality when setting the objective function. By solving the models, we can distribute the dynamic railcar flows to the train paths in the basic train timetable to obtain the daily train operation plan over a short time horizon (e.g. a day), which will be helpful for dispatchers to make decisions such as the empty railcar distribution and car routing (trip planning). Finally, we compared two models on a part of the Chinese railroad network. The results show that the second model can effectively improve the efficiency of railroad freight transportation

UniBriVL: Robust Universal Representation and Generation of Audio Driven Diffusion Models

Multimodal large models have been recognized for their advantages in various performance and downstream tasks. The development of these models is crucial towards achieving general artificial intelligence in the future. In this paper, we propose a novel universal language representation learning method called UniBriVL, which is based on Bridging-Vision-and-Language (BriVL). Universal BriVL embeds audio, image, and text into a shared space, enabling the realization of various multimodal applications. Our approach addresses major challenges in robust language (both text and audio) representation learning and effectively captures the correlation between audio and image. Additionally, we demonstrate the qualitative evaluation of the generated images from UniBriVL, which serves to highlight the potential of our approach in creating images from audio. Overall, our experimental results demonstrate the efficacy of UniBriVL in downstream tasks and its ability to choose appropriate images from audio. The proposed approach has the potential for various applications such as speech recognition, music signal processing, and captioning systems.Comment: Voice-Text fusion input; The first work of audio driven diffusion model. arXiv admin note: text overlap with arXiv:2303.0458

The manufacturing of lactobacillus microcapsules by freezing with egg yolk: The analysis of microstructure and the preservation effect against freezing and acid treatments

Encapsulation is an effective strategy to prevent probiotics from environmental damages. The survivability of Lactobacillus is generally reduced under frozen or acid environments. In this study, an attempt was made to encapsulate Lactobacillus into the egg yolk aggregates formed upon freezing. Lactobacillus broth was mixed with liquid egg yolk and frozen at selected temperatures and time periods. After thawing, the number of surviving bacteria was determined. The results showed that freezing with the addition of egg yolk improved Lactobacillus survivability. It was confirmed that freezing increased the number of egg yolk aggregates, and those aggregates coated Lactobacillus after freezing. The encapsulated Lactobacillus was treated at pH 2.5 for 10 min, and the results showed that the encapsulation process increased the acid resistance of Lactobacillus. These results indicate that freezing-induced encapsulation with egg yolk could effectively protect Lactobacillus against freezing and acid treatment. This finding could be useful for the design and preservation of probiotics-based food products

4-Benzyl-4-ethyl­morpholin-1-ium hexa­fluoro­phosphate

The asymmetric unit of the title compound, C13H20NO+·PF6 −, contains two cations, one complete anion and two half hexa­fluoro­phosphate anions having crystallographically imposed twofold rotation symmetry. In the cations, the morpholine rings are in a chair conformation. In the crystal, ions are linked by weak C—H⋯F hydrogen bonds into a three-dimensional network

Probing the IGM/Galaxy Connection IV: The LCO/WFCCD Galaxy Survey of 20 Fields Surrounding UV Bright Quasars

We publish the survey for galaxies in 20 fields containing ultraviolet bright quasars (with z_em 0.1 to 0.5) that can be used to study the association between galaxies and absorption systems from the low-z intergalactic medium (IGM). The survey is magnitude limited (R~19.5 mag) and highly complete out to 10' from the quasar in each field. It was designed to detect dwarf galaxies (L ~ 0.1 L*) at an impact parameter rho 1Mpc (z=0.1) from a quasar. The complete sample (all 20 fields) includes R-band photometry for 84718 sources and confirmed redshifts for 2800 sources. This includes 1198 galaxies with 0.005 < z < (z_em - 0.01) at a median redshift of 0.18, which may associated with IGM absorption lines. All of the imaging was acquired with cameras on the Swope 40" telescope and the spectra were obtained via slitmask observations using the WFCCD spectrograph on the Dupont 100" telescope at Las Campanas Observatory (LCO). This paper describes the data reduction, imaging analysis, photometry, and spectral analysis of the survey. We tabulate the principal measurements for all sources in each field and provide the spectroscopic dataset online.Comment: Accepted to the Astrophysical Journal Supplements; 20 pages, only 6 figures shown in this version. See http://www.ucolick.org/~xavier/WFCCDOVI/index.html for a full-length manuscript and other supportive materia