135 research outputs found

    Activities and Role of School-Based Counselors in the US: A National Survey of American Counseling Association Members

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    This study was conducted to determine: how a US sample of American Counseling Association (ACA) affiliated school-based counselors viewed their role; the extent to which various activities were practiced; and, how demographic variables (e.g., work setting and professional identity) were related to both perceptions of role and practice. Participants (N = 249) completed the International Survey of School Counselors Activities-US (ISSA-US) online, which measured both perceptions of the appropriateness of 42 activities and whether these activities are reported to be enacted. US counselors had a broad definition of their role and showed a high degree of consensus regarding the appropriateness of activities. Grade level proved to be an important determinate of the level of enactment of both group counseling and college and career counseling. The implications for of these findings for redefining the role of school counselors in the US and for international comparative research are discussed

    Restoration of Noradrenergic Function in Parkinson’s Disease Model Mice

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    Dysfunction of the central noradrenergic and dopaminergic systems is the primary neurobiological characteristic of Parkinson’s disease (PD). Importantly, neuronal loss in the locus coeruleus (LC) that occurs in early stages of PD may accelerate progressive loss of dopaminergic neurons. Therefore, restoring the activity and function of the deficient noradrenergic system may be an important therapeutic strategy for early PD. In the present study, the lentiviral constructions of transcription factors Phox2a/2b, Hand2 and Gata3, either alone or in combination, were microinjected into the LC region of the PD model VMAT2 Lo mice at 12 and 18 month age. Biochemical analysis showed that microinjection of lentiviral expression cassettes into the LC significantly increased mRNA levels of Phox2a, and Phox2b, which were accompanied by parallel increases of mRNA and proteins of dopamine β-hydroxylase (DBH) and tyrosine hydroxylase (TH) in the LC. Furthermore, there was considerable enhancement of DBH protein levels in the frontal cortex and hippocampus, as well as enhanced TH protein levels in the striatum and substantia nigra. Moreover, these manipulations profoundly increased norepinephrine and dopamine concentrations in the striatum, which was followed by a remarkable improvement of the spatial memory and locomotor behavior. These results reveal that over-expression of these transcription factors in the LC improves noradrenergic and dopaminergic activities and functions in this rodent model of PD. It provides the necessary groundwork for the development of gene therapies of PD, and expands our understanding of the link between the LC-norepinephrine and dopamine systems during the progression of PD

    Exact solution and surface critical behaviour of open cyclic SOS lattice models

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    We consider the LL-state cyclic solid-on-solid lattice models under a class of open boundary conditions. The integrable boundary face weights are obtained by solving the reflection equations. Functional relations for the fused transfer matrices are presented for both periodic and open boundary conditions. The eigen-spectra of the unfused transfer matrix is obtained from the functional relations using the analytic Bethe ansatz. For a special case of crossing parameter λ=π/L\lambda=\pi/L, the finite-size corrections to the eigen-spectra of the critical models are obtained, from which the corresponding conformal dimensions follow. The calculation of the surface free energy away from criticality yields two surface specific heat exponents, αs=2L/2\alpha_s=2-L/2\ell and α1=1L/\alpha_1=1-L/\ell, where =1,2,,L1\ell=1,2,\cdots,L-1 coprime to LL. These results are in agreement with the scaling relations αs=αb+ν\alpha_s=\alpha_b+\nu and α1=αb1\alpha_1=\alpha_b-1.Comment: 13 pages, LaTeX, to appear in J. Phys.

    Observation of the Singly Cabibbo-Suppressed Decay Λc+ΣK+π+\Lambda_{c}^{+}\to \Sigma^{-}K^{+}\pi^{+}

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    The singly Cabibbo-suppressed decay Λc+ΣK+π+\Lambda_{c}^{+}\to \Sigma^{-}K^{+}\pi^{+} is observed for the first time with a statistical significance of 6.4σ6.4\sigma by using 4.5 fb1^{-1} of e+ee^+e^- collision data collected at center-of-mass energies between 4.600 and 4.699 GeV with the BESIII detector at BEPCII. The absolute branching fraction of Λc+ΣK+π+\Lambda_{c}^{+}\to \Sigma^{-}K^{+}\pi^{+} is measured to be (3.8±1.3stat±0.2syst)×104(3.8\pm1.3_{\rm stat}\pm0.2_{\rm syst})\times 10^{-4} in a model-independent approach. This is the first observation of a Cabibbo-suppressed Λc+\Lambda_{c}^{+} decay involving Σ\Sigma^- in the final state. The ratio of branching fractions between Λc+ΣK+π+\Lambda_{c}^{+}\to \Sigma^{-}K^{+}\pi^{+} and the Cabibbo-favored decay Λc+Σπ+π+\Lambda_{c}^{+}\to \Sigma^- \pi^+\pi^+ is calculated to be (0.4±0.1)sc2(0.4 \pm 0.1)s_{c}^{2}, where scsinθc=0.2248s_{c} \equiv \sin\theta_c = 0.2248 with θc\theta_c the Cabibbo mixing angle. This ratio significantly deviates from 1.0sc21.0s_{c}^{2} and provides important information for the understanding of nonfactorization contributions in Λc+\Lambda_{c}^{+} decays.Comment: 8 pages, 2 figure

    Study of the doubly Cabibbo-suppressed decays Ds+K+K+πD^+_s\to K^+K^+\pi^- and Ds+K+K+ππ0D^+_s\to K^+K^+\pi^-\pi^0

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    Based on 7.33 fb1^{-1} of e+ee^+e^- collision data collected at center-of-mass energies between 4.128 and 4.226 GeV with the BESIII detector, the experimental studies of the doubly Cabibbo-suppressed decays Ds+K+K+πD^+_s\to K^+K^+\pi^- and Ds+K+K+ππ0D^+_s\to K^+K^+\pi^-\pi^0 are reported. We determine the absolute branching fraction of Ds+K+K+πD^+_s\to K^+K^+\pi^- to be (1.230.25+0.28(stat)±0.06(syst){1.23^{+0.28}_{-0.25}}({\rm stat})\pm0.06({\rm syst})) ×104\times 10^{-4}. No significant signal of Ds+K+K+ππ0D^+_s\to K^+K^+\pi^-\pi^0 is observed and the upper limit on its decay branching fraction at 90\% confidence level is set to be 1.7×1041.7\times10^{-4}.Comment: 10 pages, 4 figures, 4 table

    Updated measurements of the M1 transition ψ(3686)γηc(2S)\psi(3686) \to \gamma \eta_{c}(2S) with ηc(2S)KKˉπ\eta_{c}(2S) \to K \bar{K} \pi

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    Based on a data sample of (27.08±0.14)×108 ψ(3686)(27.08 \pm 0.14 ) \times 10^8~\psi(3686) events collected with the BESIII detector at the BEPCII collider, the M1 transition ψ(3686)γηc(2S)\psi(3686) \to \gamma \eta_{c}(2S) with ηc(2S)KKˉπ\eta_{c}(2S) \to K\bar{K}\pi is studied, where KKˉπK\bar{K}\pi is K+Kπ0K^{+} K^{-} \pi^{0} or KS0K±πK_{S}^{0}K^{\pm}\pi^{\mp}. The mass and width of the ηc(2S)\eta_{c}(2S) are measured to be (3637.8±0.8(stat)±0.2(syst))(3637.8 \pm 0.8 (\rm {stat}) \pm 0.2 (\rm {syst})) MeV/c2c^{2} and (10.5±1.7(stat)±3.5(syst))(10.5 \pm 1.7 (\rm {stat}) \pm 3.5 (\rm {syst})) MeV, respectively. The product branching fraction B(ψ(3686)γηc(2S))×B(ηc(2S)KKˉπ)\mathcal{B}\left(\psi(3686) \rightarrow \gamma \eta_{c}(2 S)\right) \times \mathcal{B}(\eta_{c}(2 S) \rightarrow K \bar{K} \pi) is determined to be (0.97±0.06(stat)±0.09(syst))×105(0.97 \pm 0.06 (\rm {stat}) \pm 0.09 (\rm {syst})) \times 10^{-5}. Using BR(ηc(2S)KKˉπ)=(1.860.49+0.68)%\mathcal{BR}(\eta_{c}(2S)\to K\bar{K}\pi)=(1.86^{+0.68}_{-0.49})\%, we obtain the branching fraction of the radiative transition to be BR(ψ(3686)γηc(2S))=(5.2±0.3(stat)±0.5(syst)1.4+1.9(extr))×104\mathcal{BR}(\psi(3686) \to \gamma \eta_{c}(2S)) = (5.2 \pm 0.3 (\rm {stat}) \pm 0.5 (\rm {syst}) ^{+1.9}_{-1.4} (extr)) \times 10^{-4}, where the third uncertainty is due to the quoted BR(ηc(2S)KKˉπ)\mathcal{BR}(\eta_{c}(2S) \to K\bar{K}\pi)
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