Il Nuovo soggettario in Aleph 500

This document illustrates a project for the adaptation of the ALEPH 500 software to the characteristics of the subject indexing language of "Nuovo soggettario", in respect of the international formats Unimarc/Authorities and Unimarc/Bibliographic. The base unit of the indexing language of "Nuovo soggettario", structured according to the method of GRIS (Gruppo di ricerca sull'indicizzazione per soggetto, Research Group on Subject Indexing), is the indexing term, either representing a concept or referring to an individually-named entity, in the form of a noun or noun phrase. The indexing terms are not coincident to the elements of the traditional subject headings, the so-called "descrittori" in SBN (the Italian National library service)

I titoli uniformi negli archivi di autorità di sistemi UNIMARC in colloquio con Indice, con particolare riferimento ad ALEPH 500

The Italian cataloguing code (Regole italiane di catalogazione, REICAT) requires the identification of all the works represented in the catalogue by the use of uniform titles. In the SBN-MARC protocol of the Italian National Library Service network (SBN), the authority records for the uniform titles have a different structure from the one proposed by the UNIMARC Authorities format: this prevents the respect of the cataloguing rules, the correct indexing of works and expressions and consequently their effective retrieval and display in the OPACs. This paper illustrates the problems and the possible solutions, both in the SBN-MARC protocol and in the UNIMARC systems that are hubs linked to SBN Index system, the core of the collective catalogue

Il Nuovo soggettario in Aleph 500

This document illustrates a project for the adaptation of the ALEPH 500 software to the characteristics of the subject indexing language of "Nuovo soggettario", in respect of the international formats Unimarc/Authorities and Unimarc/Bibliographic. The base unit of the indexing language of "Nuovo soggettario", structured according to the method of GRIS (Gruppo di ricerca sull'indicizzazione per soggetto, Research Group on Subject Indexing), is the indexing term, either representing a concept or referring to an individually-named entity, in the form of a noun or noun phrase. The indexing terms are not coincident to the elements of the traditional subject headings, the so-called "descrittori" in SBN (the Italian National library service)

Triazole RGD antagonist reverts TGFβ1-induced endothelial-to-mesenchymal transition in endothelial precursor cells

Fibrosis is the dramatic consequence of a dysregulated reparative process in which activated fibroblasts (myofibroblasts) and Transforming Growth Factor β1 (TGFβ1) play a central role. When exposed to TGFβ1, fibroblast and epithelial cells differentiate in myofibroblasts; in addition, endothelial cells may undergo endothelial-to-mesenchymal transition (EndoMT) and actively participate to the progression of fibrosis. Recently, the role of αv integrins, which recognize the Arg-Gly-Asp (RGD) tripeptide, in the release and signal transduction activation of TGFβ1 became evident. In this study, we present a class of triazole-derived RGD antagonists that interact with αvβ3 integrin. Above different compounds, the RGD-2 specifically interferes with integrin-dependent TGFβ1 EndoMT in Endothelial Colony-Forming Cells (ECPCs) derived from circulating Endothelial Precursor Cells (ECPCs). The RGD-2 decreases the amount of membrane-associated TGFβ1, and reduces both ALK5/TGFβ1 type I receptor expression and Smad2 phosphorylation in ECPCs. We found that RGD-2 antagonist reverts EndoMT, reducing α-smooth muscle actin (α-SMA) and vimentin expression in differentiated ECPCs. Our results outline the critical role of integrin in fibrosis progression and account for the opportunity of using integrins as target for anti-fibrotic therapeutic treatment

Relative Timing of Off-Axis Volcanism from Sediment Thickness Estimates on the 8°20’N Seamount Chain, East Pacific Rise

Volcanic seamount chains on the flanks of mid-ocean ridges record variability in magmatic processes associated with mantle melting over several millions of years. However, the relative timing of magmatism on individual seamounts along a chain can be difficult to estimate without in situ sampling and is further hampered by Ar40/Ar39 dating limitations. The 8°20’N seamount chain extends ∼170 km west from the fast-spreading East Pacific Rise (EPR), north of and parallel to the western Siqueiros fracture zone. Here, we use multibeam bathymetric data to investigate relationships between abyssal hill formation and seamount volcanism, transform fault slip, and tectonic rotation. Near-bottom compressed high-intensity radiated pulse, bathymetric, and sidescan sonar data collected with the autonomous underwater vehicle Sentry are used to test the hypothesis that seamount volcanism is age-progressive along the seamount chain. Although sediment on seamount flanks is likely to be reworked by gravitational mass-wasting and current activity, bathymetric relief and Sentry vehicle heading analysis suggest that sedimentary accumulations on seamount summits are likely to be relatively pristine. Sediment thickness on the seamounts\u27 summits does not increase linearly with nominal crustal age, as would be predicted if seamounts were constructed proximal to the EPR axis and then aged as the lithosphere cooled and subsided away from the ridge. The thickest sediments are found at the center of the chain, implying the most ancient volcanism there, rather than on seamounts furthest from the EPR. The nonlinear sediment thickness along the 8°20’N seamounts suggests that volcanism can persist off-axis for several million years

Il mercato del vino nella Grande Distribuzione Organizzata in Italia. Tendenze 2009-2017 e Previsioni.

This report analyzes the composition and trends of wine sales in the Italian large-scale retail trade in the period 2009-2017. The analysis focuses on wine sales by type of product, i.e. sales format, color, still/sparkling wine, geographical indication, sales in promotion. Specific insights regard wines in 0.75 liter glass bottles, Private Label wine and the first twenty designations of origin in terms of value sold in the large-scale distribution. Lastly, forecasting models based on quarterly time series have been developed to provide a picture of the future performance of the sector. The study allows defining appropriate strategies to be implemented to respond to new consumption trends

Il mercato del vino nella Grande Distribuzione Organizzata in Italia

This report analyzes the composition and trends of wine sales in the Italian large-scale retail trade in the period 2009-2017. The analysis focuses on wine sales by type of product, i.e. sales format, color, still/sparkling wine, geographical indication, sales in promotion. Specific insights regard wines in 0.75 liter glass bottles, Private Label wine and the first twenty designations of origin in terms of value sold in the large-scale distribution. Lastly, forecasting models based on quarterly time series have been developed to provide a picture of the future performance of the sector. The study allows defining appropriate strategies to be implemented to respond to new consumption trends