3,546 research outputs found
Innovation as socially shared practice: the contribution of the Teaching and Learning Center
The contribution describes a study on the organizational devices and the professional development programs carried
out at the Teaching and Learning Center (TLC) of the University of Siena and at the Teaching and Learning Lab
(TLL) of the University of Macerata. The focus is on systemic actions capable to elicit innovation at an organizational level, starting from the work of the institutional centers for research, professional training, and digital enhanced learning embedded in the university. In the final paragraph, future developmental trajectories for constituting an inter-universities network of TLCs are discussed
Competenze trasversali, innovazione didattica e presidi organizzativi (Cap. 4.)
Gli odierni scenari lavorativi, le nuove professioni, con i relativi bisogni di conoscenza, hanno enfatizzato le criticitĂ e le contraddizioni di approcci didattici troppo spesso ancorati a logiche teorico-disciplinari e offerte formative costruite su criteri autoreferenziali.
• Le Università progettano centri, curriculum e percorsi di apprendimento capaci di promuovere l’acquisizione di competenze pratiche utili per i futuri professionisti.
• Necessità di promuovere esperienze concrete (Teaching and Learning Center) che attivino offerte formative in grado di intercettare bisogni di apprendimento emergenti e sfidanti rispetto agli attuali scenari lavorativi, e di dialogare con gli stakeholder.
• Costruire una rete nazionale dei Teaching and Learning Center dei diversi Atenei italiani al fine di condividere esperienze di didattica innovativa e di supportare lo sviluppo delle competenze trasversali degli studenti e dei docenti
At the beginning was the decree. Towards a shared design process between insiders and outsiders
The article describes the collaborative research carried out for the co-design of the Program for professional socio-pedagogical educator. Starting from the analysis of the laws and regulations defining normative parameters, using the results of the TECO-D project, the work reconstructs the elements of the research conducted with educators working in the professional sectors interested by the Program. The collaborative methodology implemented has made possible identifying four core contents: situated theories, methodologies of investigation, verification of the effectiveness of the educational action, conflicts between colleagues. In principio era il decreto. Verso una progettazione condivisa tra insider e outsiderIl contributo descrive la ricerca collaborativa condotta per la co-progettazione del Corso intensivo di formazione per la qualifica di educatore professionale socio-pedagogico. Partendo dall’analisi della traiettoria legislativa che ne ha definito normativamente i parametri, utilizzando il lavoro di ricerca svolto nel progetto TECO-D, si arriva a ricostruire gli elementi della ricerca condotta insieme ad educatori e coordinatori dei servizi che operano nei settori professionali interessati dal corso di formazione. La metodologia collaborativa attuata ha permesso di individuare quattro contenuti ritenuti centrali dai partecipanti alla ricerca: Teorie situate, metodologie d’indagine, verifica dell’efficacia dell’azione educativa, conflitti tra colleghi
Impact of size effects on photopolymerization and its optical monitoring in-situ
Photopolymerization processes are exploited in light exposure-based 3D printing technologies, where either a focused laser beam or a patterned light sheet allows layers of a UV curable, liquid pre-polymer to be solidified. Here we focus on the crucial, though often neglected, role of the layer thickness on photopolymerization. The temporal evolution of polymerization reactions occurring in droplets of acrylate-based oligomers and in photoresist films with varied thickness is investigated by means of an optical system, which is specifically designed for in-situ and real-time monitoring. The time needed for complete curing is found to increase as the polymerization volume is decreased below a characteristic threshold that depends on the specific reaction pathway. This behavior is rationalized by modeling the process through a size-dependent polymerization rate. Our study highlights that the formation of photopolymerized networks might be affected by the involved volumes regardless of the specific curing mechanisms, which could play a crucial role in optimizing photocuring-based additive manufacturing
Assembly of Pt nanoparticles on graphitized carbon nanofibers as hierarchically structured electrodes
Carbon-based nanofibers decorated with metallic nanoparticles (NPs) as hierarchically structured electrodes offer significant opportunities for use in low-temperature fuel cells, electrolyzers, flow and air batteries, and electrochemical sensors. We present a facile and scalable method for preparing nanostructured electrodes composed of Pt NPs on graphitized carbon nanofibers. Electrospinning directly addresses the issues related to large-scale production of Pt-based fuel cell electrocatalysts. Through precursors containing polyacrylonitrile and Pt salt electrospinning along with an annealing protocol, we obtain approximately 180 nm thick graphitized nanofibers decorated with approximately 5 nm Pt NPs. By in situ annealing scanning transmission electron microscopy, we qualitatively resolve and quantitatively analyze the unique dynamics of Pt NP formation and movement. Interestingly, by very efficient thermal-induced segregation of all Pt from the inside to the surface of the nanofibers, we increase overall Pt utilization as electrocatalysis is a surface phenomenon. The obtained nanomaterials are also investigated by spatially resolved Raman spectroscopy, highlighting the higher structural order in nanofibers upon doping with Pt precursors. The rationalization of the observed phenomena of segregation and ordering mechanisms in complex carbon-based nanostructured systems is critically important for the effective utilization of all metal-containing catalysts, such as electrochemical oxygen reduction reactions, among many other applications
Prenatal diagnosis and post-mortem examination in a fetus with thrombocytopenia-absent radius (TAR) syndrome due to compound heterozygosity for a 1q21.1 microdeletion and a RBM8A hypomorphic allele: a case report
Background: Thrombocytopenia-absent radius syndrome is a rare autosomal recessive disorder characterized by megakaryocytic thrombocytopenia and longitudinal limb deficiencies mostly affecting the radial ray. Most patients are compound heterozygotes for a 200 kb interstitial microdeletion in 1q21.1 and a hypomorphic allele in RBM8A, mapping in the deleted segment. At the moment, the complete molecular characterization of thrombocytopenia-absent radius syndrome is limited to a handful of patients mostly ascertained in the pediatric age. Case presentation. We report on a fetus with bilateral upper limb deficiency found at standard prenatal ultrasound examination. The fetus had bilateral radial agenesis and humeral hypo/aplasia with intact thumbs, micrognathia and urinary anomalies, indicating thrombocytopenia-absent radius syndrome. Molecular studies demonstrated compound heterozygosity for the 1q21.1 microdeletion and the RBM8A rs139428292 variant at the hemizygous state, inherited from the mother and father, respectively. Conclusion: The molecular information allowed prenatal diagnosis in the following pregnancy resulting in the birth of a healthy carrier female. A review was carried out with the attempt to the trace the fetal ultrasound presentation of thrombocytopenia-absent radius syndrome and discussing opportunities for second-tier molecular studies within a multidisciplinary setting. © 2013 Bottillo et al.; licensee BioMed Central Ltd
Gas Analysis and Monitoring Systems for the RPC Detector of CMS at LHC
The Resistive Plate Chambers (RPC) detector of the CMS experiment at the LHC
proton collider (CERN, Switzerland) will employ an online gas analysis and
monitoring system of the freon-based gas mixture used. We give an overview of
the CMS RPC gas system, describe the project parameters and first results on
gas-chromatograph analysis. Finally, we report on preliminary results for a set
of monitor RPC.Comment: 9 pages, 8 figures. Presented by Stefano Bianco (Laboratori Nazionali
di Frascati dell'INFN) at the IEEE NSS, San Diego (USA), October 200
The CMS RPC gas gain monitoring system: an overview and preliminary results
The status of the CMS RPC Gas Gain Monitoring (GGM) system developed at the
Frascati Laboratory of INFN (Istituto Nazionale di Fisica Nucleare) is reported
on. The GGM system is a cosmic ray telescope based on small RPC detectors
operated with the same gas mixture used by the CMS RPC system. The GGM gain and
efficiency are continuously monitored on-line, thus providing a fast and
accurate determination of any shift in working point conditions. The
construction details and the first result of GGM commissioning are described.Comment: 8 pages, 9 figures, uses lnfprepCMS.sty, presented by L. Benussi at
RPC07, Mumbai, INDIA 200
Lack of efficacy of convalescent plasma in COVID-19 patients with concomitant hematological malignancies: An Italian retrospective study
A multicenter retrospective study was designed to assess clinical outcome of COVID-19 in patients with hematological malignancies (HM) following treatment with anti-SARS-CoV-2 convalescent plasma (CP) or standard of care therapy. To this aim, a propensity score matching was used to assess the role of non-randomized administration of CP in this high-risk cohort of patients from the Italian Hematology Alliance on COVID-19 (ITA-HEMA-COV) project, now including 2049 untreated control patients. We investigated 30- and 90-day mortality, rate of admission to intensive care unit, proportion of patients requiring mechanical ventilatory support, hospitalization time, and SARS-CoV-2 clearance in 79 CP recipients and compared results with 158 propensity score-matched controls. Results indicated a lack of efficacy of CP in the study group compared with the untreated group, thus confirming the negative results obtained from randomized studies in immunocompetent individuals with COVID-19. In conclusion, this retrospective analysis did not meet the primary and secondary end points in any category of immunocompromized patients affected by HM
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