Building a Sustainable Learning Cycle: The Role of ‘the Formative Use of Summative Tests’ (FUST) in Promoting Students’ Developments

The study employed a descriptive mixed-methods qualitative case study approach. Material and interview-based data were collected from two EFL classes in a private international school in central China. Findings from RQ1 suggest that teacher-made summative tests were largely dependable to the extent that the tests reflect the syllabus-based construct and address students’ affective factors. Findings from RQ2 suggest that facilitating factors including in-school continuous professional development (CPD) and teacher collegiality practices may enhance FUST’s prospective role

Feature Selective Networks for Object Detection

Objects for detection usually have distinct characteristics in different sub-regions and different aspect ratios. However, in prevalent two-stage object detection methods, Region-of-Interest (RoI) features are extracted by RoI pooling with little emphasis on these translation-variant feature components. We present feature selective networks to reform the feature representations of RoIs by exploiting their disparities among sub-regions and aspect ratios. Our network produces the sub-region attention bank and aspect ratio attention bank for the whole image. The RoI-based sub-region attention map and aspect ratio attention map are selectively pooled from the banks, and then used to refine the original RoI features for RoI classification. Equipped with a light-weight detection subnetwork, our network gets a consistent boost in detection performance based on general ConvNet backbones (ResNet-101, GoogLeNet and VGG-16). Without bells and whistles, our detectors equipped with ResNet-101 achieve more than 3% mAP improvement compared to counterparts on PASCAL VOC 2007, PASCAL VOC 2012 and MS COCO datasets

Ordering policies for a dual sourcing supply chain with disruption risks

Purpose: The main purpose of this article is to explore the trade-off between ordering policies and disruption risks in a dual-sourcing network under specific (or not) service level constraints, assuming that both supply channels are susceptible to disruption risks. Design/methodology/approach: Stochastic newsvendor models are presented under both the unconstrained and fill rate constraint cases. The models can be applicable for different types of disruptions related among others to the supply of raw materials, the production process, and the distribution system, as well as security breaches and natural disasters. Findings: Through the model, we obtain some important managerial insights and evaluate the value of contingency strategies in managing uncertain supply chains. Originality/value: This paper attempts to combine explicitly disruption management with risk aversion issues for a two-stage supply chain with two unreliable suppliers.Peer Reviewe

Teaching Literary Reading for Transfer: Hugging and Bridging Designed

As researchers are looking for different strategies to reform on a straightforwardly presented instruction in the English literature classroom, the specific ends of teaching literature for transfer are sometimes neglected. That does not mean transfer is not valid in a literature course, but teachers should design a course persistently and systematically enough to foster transfer. This study revisits the hugging-bridging framework to explore the instructor methods in a literary reading course and suggests creative writing as a hub of teaching transfer. Main focus would be given to the design of hugging in class reading instruction and bridging in transferable task of writing. Though effective transfer is decided by students’ familiarity with the knowledge and proficiency in using certain knowledge, learning for transfer could be conducive to shaping a routine problem- minded concept for learners

Reconfi guration analysis of carrier security system for IPv6

With the continuous development of the Internet, IPv6 planning and deployment has become the current “accelerate the construction of network power, to win the future international competition of new advantages” an urgent requirement, and the current security system reconstruction in the implementation of IPv6 planning and deployment plan has a very important practical promotion signifi cance. However, we should pay attention to one point is that compared with the Internet construction and operation and maintenance, the operator IPv6 network construction and its security operation and maintenance is a certain difference. Therefore, based on the background of the new era, it is very necessary to actively explore the path of IPv6 oriented carrier security system reconstruction planning. Based on this, this paper fi rst describes the application advantages of IPv6, and briefl y analyzes the status quo of the carrier security system, and discusses the reconstruction direction and planning of the IPv6 oriented carrier security system, for reference only

Cytotoxic activity of lithospermum erythrorhizon root extract against childhood acute leukemia cells via regulation of PI3K/AKT/mTOR pathway

Purpose: To investigate the effect and mechanism of action of Lithospermum erythrorhizon root extract (LR) in childhood acute leukemia. Methods: Human leukemic lymphoblast (CCRF-CEM cell line) cells were treated with LR (2, 4, and 8 mg/mL). Cell viability, cell apoptosis and cell cycle were measured using 3-(4,5-dimethylthiazol-2- thiazolyl)-2,5-diphenyltetrazolium bromide (MTT) assay and flow cytometry, respectively. The levels of cell-cycle-related proteins including cyclin D1, cyclin E1, cyclin-dependent kinase 2 (CDK2), CDK4 and CDK6, as well as cleaved caspase 3, cleaved caspase 9 and Bcl-2-associated x (Bax). Also determined were B-cell lymphoma-2 (Bcl-2), E-cadherin, N-cadherin, vimentin, zonula occludens 1 (ZO-1), matrix metalloproteinase-2 (MMP-2) and MMP-9. Cell migration and invasion were assessed using scratch and Transwell assays. Finally, phosphoinositide 3-kinase (PI3K), phosphorylated serine/threonine kinase (pAKT), total AKT (t-AKT), mammalian target of rapamycin (mTOR), and phosphorylated mTOR (pmTOR) were measured using western blotting. Results: Lithospermum erythrorhizon root extract not only dose-dependently inhibited cell viability, induced G1 phase accumulation, and downregulated CDK2, CDK4, CDK6, cyclin D1, and cyclin E1, but also elevated apoptosis, cleaved caspase 3, cleaved caspase 9, and Bax and decreased Bcl-2 expression levels. In addition, Lithospermum erythrorhizon root extract suppressed migration and invasion of CCRF-CEM cells, downregulated N-cadherin, vimentin, MMP-2, and MMP-9, and upregulated E-cadherin and ZO-1. Moreover, Lithospermum erythrorhizon root extracts dosedependently inhibited PI3K, p-AKT (ser473)/t-AKT, p-mTOR (ser2448)/mTOR, and p-mTOR (ser2481)/mTOR. Conclusion: The findings provide a potential therapeutic approach to the treatment of childhood acute leukemia