14 research outputs found

    erratum to superlubricity of epitaxial monolayer ws2 on graphene

    Get PDF
    The article Superlubricity of epitaxial monolayer WS2 on graphene, written by Holger Buch, Antonio Rossi, Stiven Forti, Domenica Convertino, Valentina Tozzini, and Camilla Coletti, was originally published electronically on the publisher's internet portal (currently SpringerLink) on June 18th 2018 without open access. With the author(s)' decision to opt for Open Choice the copyright of the article changed in August 2018 to © The Author(s) 2018 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/ ), which permits use, duplication, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made. The original article has been corrected

    Metabolically healthy polycystic ovary syndrome (MH-PCOS) and metabolically unhealthy polycystic ovary syndrome (MU-PCOS): a comparative analysis of four simple methods useful for metabolic assessment.

    Get PDF
    study question:Is it possible to distinguish metabolically healthy polycystic ovary syndrome (MH-PCOS) from metabolically un-healthy PCOS (MU-PCOS) by simple diagnostic tools such as body mass index (BMI), waist/hip ratio (WHR), at-risk category suggestedby Androgen Excess Society (AES) and visceral adiposity index (VAI)?summary answer:VAI could be an easy and useful tool in clinical practice and in population studies for assessment of MU-PCOS.what is known already:VAI is a good indicator of insulin sensitivity and cardiometabolic risk in oligo-ovulatory women withPCOS.study design, size, duration:We conducted a cross-sectional study of 232 women with PCOS in a university hospital setting.participants/materials, setting, methods:Anthropometric, hormonal and metabolic parameters were evaluated. Anoral glucose tolerance test measured areas under the curve (AUC) for insulin (AUC2h insulin) and for glucose (AUC2h glucose). Homeostasismodel assessment of insulin resistance (HOMA2-IR), the Matsuda index of insulin sensitivity (ISI), the oral dispositional index (DIo) and VAIwere determined.main results and the role of chance:The prevalence of MU-PCOS according to the different criteria was: BMI, 56.0%;WHR, 18.1%; at-risk criteria of AES, 72.0% and VAI, 34.5%. The likelihood that a woman would exhibit MU-PCOS (except when diagnosedby the WHR criterion) showed a significant positive association with high HOMA2-IR [BMI criterion: (odds ratio (OR): 1.86; 95% confidenceinterval (CI): 1.43–2.41); risk criteria of AES (OR: 1.86; 95% CI: 1.36–2.56); VAI criterion (OR: 1.45; 95% CI: 1.17–1.80)] and a significantnegative association with low ISI Matsuda [BMI criterion: (OR: 0.81; 95% CI: 0.72–0.91); risk criteria of AES (OR: 0.78; 95% CI: 0.69–0.89);VAI criterion (OR: 0.82; 95% CI: 0.71–0.94)]. Only MU-PCOS according to the VAI criterion showed a significant association with low DIo(OR: 0.85; 95% CI: 0.75–0.96); these women also showed a significant association with low luteal progesterone levels (OR: 0.97; 95% CI:0.95–0.99).limitations, reasons for caution:The analysis is limited by the lack of a gold standard definition of metabolic health thatwould have allowed the execution of a receiver operator characteristic analysis of the four proposed criteria.wider implications of the findings:The results will facilitate the early recognition of cardiometabolic risk in women withPCOS before they develop overt metabolic syndrome

    Premorbid Adjustment and IQ in Patients With First-Episode Psychosis: A Multisite Case-Control Study of Their Relationship With Cannabis Use.

    Get PDF
    Psychotic patients with a lifetime history of cannabis use generally show better cognitive functioning than other psychotic patients. Some authors suggest that cannabis-using patients may have been less cognitively impaired and less socially withdrawn in their premorbid life. Using a dataset comprising 948 patients with first-episode psychosis (FEP) and 1313 population controls across 6 countries, we examined the extent to which IQ and both early academic (Academic Factor [AF]) and social adjustment (Social Factor [SF]) are related to the lifetime frequency of cannabis use in both patients and controls. We expected a higher IQ and a better premorbid social adjustment in psychotic patients who had ever used cannabis compared to patients without any history of use. We did not expect such differences in controls. In both patients and controls, IQ was 3 points higher among occasional-users than in never-users (mean difference [Mdiff] = 2.9, 95% CI = [1.2, 4.7]). Both cases and control daily-users had lower AF compared to occasional (Mdiff = -0.3, 95% CI = [-0.5; -0.2]) and never-users (Mdiff = -0.4, 95% CI = [-0.6; -0.2]). Finally, patient occasional (Mdiff = 0.3, 95% CI = [0.1; 0.5]) and daily-users (Mdiff = 0.4, 95% CI = [0.2; 0.6]) had better SF than their never-using counterparts. This difference was not present in controls (Fgroup*frequency(2, 2205) = 4.995, P = .007). Our findings suggest that the better premorbid social functioning of FEP with a history of cannabis use may have contributed to their likelihood to begin using cannabis, exposing them to its reported risk-increasing effects for Psychotic Disorders
    corecore