The thermal and detailed kinetic analysis of dipicolinate complexes

The [Cu(pydc)(eim)(3)]center dot H2O(1), [Cu(pydc)(4hp)(H2O)] (2) and [Ni(pydc)(3hp)(H2O)(2)][Cu(pydc)(3hp)(H2O)(2)]center dot 3H(2)O (3) complexes (H(2)pydc = 2,6-pyridinedicarboxylic acid or dipicolinic acid, eim = 2-ethylimidazole, 4hp = 4-hydroxypyridine, 3hp = 3-hydroxypyridine) were studied by thermo-gravimetric analysis at an ambient temperature up to 1000 K under nitrogen atmosphere. The complexes are stable about 350 K, and the decomposition reactions were carried out in seven, three and four stages for the complexes 1, 2 and 3, respectively. Following detailed thermogravimetrical analysis of the complexes, the decomposition mechanism was suggested for all complexes. The kinetic analysis of all decomposition stages of each compound was performed except for the final stages. The values of the activation energy, Ea, were obtained using model-free Kissinger-Akahira-Sunose and Flyn-Wall-Ozawa methods for all decomposition stages

Syntheses of crystal structures and in vitro cytotoxic activities of new copper(II) complexes of pyridine-2,6-dicarboxylate

TAS, MURAT/0000-0002-2879-6501; Koyundereli CILGI, Gulbanu/0000-0002-0016-019XWOS: 000362682600005[Cu(pydc)(im)](n) (1), [Cu(pydc)(mim)(3)].2H(2)O (2), [Cu(pydc)(ampy)(H2O)].H2O (3), and [Cu(pydc)(phen)][Cu(Hpydc)(2)] (4) (H(2)pydc=2,6-pyridinedicarboxylic acid or dipicolinic acid, im=imidazole, mim=2-methylimidazole, ampy=2-amino-4-methylpyridine, and phen=1,10-phenanthroline) were synthesized and characterized by elemental analysis, spectroscopic measurements (UV-vis and IR spectra) and single crystal X-ray diffraction. Complexes 1, 2 and 3 were studied by thermogravimetric analysis from ambient temperature to 1100K under nitrogen and thermal stabilities were investigated. The effects of complexes on proliferation of fibrosarcoma cells were investigated using the Quick Cell Proliferation Assay. The cell viability changes depend on the concentrations and type of complexes. According to cell proliferation/viability data, 4 was determined to be the most cytotoxic.Dumlupinar UniversityDumlupinar University [20012/22]This work was supported by Dumlupinar University [project number 20012/22]

Minutes, April 19, 1972

[Cu(pydc)(eim)(3)].H2O (1), [Cu(pydc)(4hp)(H2O)] (2), and [Ni(pydc)(3hp)(H2O)(2)][Cu(pydc)(3hp)(H2O)(2)].3H(2)O (3) (H(2)pydc=2,6-pyridinedicarboxylic acid or dipicolinic acid, eim=2-ethylimidazole, 4hp=4-hydroxypyridine, 3hp=3-hydroxypyridine) were synthesized and characterized by elemental analysis, spectroscopic measurements (UV-vis and IR spectra), and single-crystal X-ray diffraction. Crystal analysis revealed that the complexes extended to 3-D supramolecular networks through intermolecular H-bonding and molecular interactions between the ligand moieties and water molecules. The thermal stabilities of complexes are investigated by thermogravimetry, differential thermogravimetry, and differential thermal analysis techniques. The effects of complexes on the proliferation of HT-1080 fibrosarcoma cells were investigated using the quick cell proliferation assay. The cell viability changes were found to depend on the concentrations and type of complex