Stretched Polymers in Random Environment

We survey recent results and open questions on the ballistic phase of stretched polymers in both annealed and quenched random environments.Comment: Dedicated to Erwin Bolthausen on the occasion of his 65th birthda

Mechanical concept of the neurosurgical robot ‘Minerva'

We describe a robot capable of performing all procedures necessary to carry out a complete stereotactic neurosurgical operation under the control and supervision of a surgeon. The operation consists of the introduction of a small probe with diameter 2-3 mm through a hole without trepanation. The robot has been built and is now being tested and evaluated. The accompanying control software as well as various medical probes are either in development or partially tested. The installation will be able to carry out a complete intervention under the surveillance of a computed tomography scanner. In this article we emphasize the design choices required to eliminate gearing backlash in a crucial degree of freedo

Routing stemflow water through the soil via preferential flow: a dual-labelling approach with artificial tracers

Stemflow and its belowground funnelling along roots and macropores may play an important role in the soil moisture redistribution in forest environments. In this study, a stemflow experiment on Pinus sylvestris L. (Scots pine) used artificial tracers to view and quantify preferential flow after stemflow infiltration into the soil. A total of 41 L of water labelled with enriched deuterium and brilliant blue FCF were applied at a flow rate of 7 L h−1 to the stem of a pine tree, which corresponds to the stemflow caused by about 50 mm of rainfall. Time domain reflectometry (TDR) probes were installed around the tree trunk to measure the high-resolution volumetric water content. A total of 1 d after the stemflow discharge, soil pits were dug in the different cardinal directions and at varying distances from the tree. Photographs were taken for imaging analysis to quantify preferential flow metrics. Soil samples were taken from the different profiles to analyse the dye concentrations and isotopic compositions. We found that stemflow infiltrated through an annulus-shaped area around the tree base. We observed a heterogenous spatiotemporal soil moisture response to stemflow and the occurrence of shallow perched water tables around the tree trunk. Dye staining demonstrated that stemflow infiltrated primarily along the surface of coarse roots and through macropores. The dye coverage was less extensive close to the soil surface and increased with depth and with proximity to the tree trunk. Lateral flow was also observed, mainly in the shallow soil layers. Our analyses demonstrate the prevalence of preferential flow. Deuterium and brilliant blue FCF concentrations were significantly correlated. The tracer concentrations decreased with increasing distance from the tree trunk, indicating dilution and mixing with residual soil water. Macropores, coarse roots (living or decayed) and perched water tables produced a complex network regulating the preferential flow. Our results suggest that stemflow affects soil moisture distribution, and thus likely also groundwater recharge and surface runoff. Our study provides insights into the soil hydrological processes that are regulated by stemflow belowground funnelling and improves our understanding of forest–water interactions.</p

Lyapunov exponents of Green's functions for random potentials tending to zero

We consider quenched and annealed Lyapunov exponents for the Green's function of $-\Delta+\gamma V$, where the potentials $V(x), x\in\Z^d$, are i.i.d. nonnegative random variables and $\gamma>0$ is a scalar. We present a probabilistic proof that both Lyapunov exponents scale like $c\sqrt{\gamma}$ as $\gamma$ tends to 0. Here the constant $c$ is the same for the quenched as for the annealed exponent and is computed explicitly. This improves results obtained previously by Wei-Min Wang. We also consider other ways to send the potential to zero than multiplying it by a small number.Comment: 16 pages, 3 figures. 1 figure added, very minor corrections. To appear in Probability Theory and Related Fields. The final publication is available at http://www.springerlink.com, see http://www.springerlink.com/content/p0873kv68315847x/?p=4106c52fc57743eba322052bb931e8ac&pi=21

Depth-resolved local reflectance spectra measurements in full-field optical coherence tomography

Full-field optical coherence tomography (FF-OCT) is a widely used technique for applications such as biological imaging, optical metrology, and materials characterization, providing structural and spectral information. By spectral analysis of the backscattered light, the technique of spectroscopic-OCT enables the differentiation of structures having different spectral properties, but not the determination of their reflectance spectrum. For surface measurements, this can be achieved by applying a Fourier transform to the interferometric signals and using an accurate calibration of the optical system. An extension of this method is reported for local spectroscopic characterization of transparent samples and in particular for the determination of depth-resolved reflectance spectra of buried interfaces. The correct functioning of the method is demonstrated by comparing the results with those obtained using a program based on electromagnetic matrix methods for stratified media. Experimental measurements of spatial resolutions are provided to demonstrate the smallest structures that can be characterized

Using digital and hand printing techniques to compensate for loss: re-establishing colour and texture in historic textiles

Conservators use a range of 'gap filling' techniques to improve the structural stability and presentation of objects. Textile conservators often use fabric supports to provide reinforcement for weak areas of a textile and to provide a visual infill in missing areas. The most common technique is to use dyed fabrics of a single colour but while a plain dyed support provides good reinforcement, it can be visually obtrusive when used with patterned or textured textiles. Two recent postgraduate dissertation projects at the Textile Conservation Centre (TCC) have experimented with hand printing and digital imaging techniques to alter the appearance of support fabrics so that they are less visually obtrusive and blend well with the colour and texture of the textile being supported. Case studies demonstrate the successful use of these techniques on a painted hessian rocking horse and a knitted glove from an archaeological context

Persistence of root-colonizing Pseudomonas protegens in herbivorous insects throughout different developmental stages and dispersal to new host plants.

The discovery of insecticidal activity in root-colonizing pseudomonads, best-known for their plant-beneficial effects, raised fundamental questions about the ecological relevance of insects as alternative hosts for these bacteria. Since soil bacteria are limited in their inherent abilities of dispersal, insects as vectors might be welcome vehicles to overcome large distances. Here, we report on the transmission of the root-colonizing, plant-beneficial and insecticidal bacterium Pseudomonas protegens CHA0 from root to root by the cabbage root fly, Delia radicum. Following ingestion by root-feeding D. radicum larvae, CHA0 persisted inside the insect until the pupal and adult stages. The emerging flies were then able to transmit CHA0 to a new plant host initiating bacterial colonization of the roots. CHA0 did not reduce root damages caused by D. radicum and had only small effects on Delia development suggesting a rather commensal than pathogenic relationship. Interestingly, when the bacterium was fed to two highly susceptible lepidopteran species, most of the insects died, but CHA0 could persist throughout different life stages in surviving individuals. In summary, this study investigated for the first time the interaction of P. protegens CHA0 and related strains with an insect present in their rhizosphere habitat. Our results suggest that plant-colonizing pseudomonads have different strategies for interaction with insects. They either cause lethal infections and use insects as food source or they live inside insect hosts without causing obvious damages and might use insects as vectors for dispersal, which implies a greater ecological versatility of these bacteria than previously thought

Depth-resolved local reflectance spectra measurements in full-field optical coherence tomography

Full-field optical coherence tomography (FF-OCT) is a widely used technique for applications such as biological imaging, optical metrology, and materials characterization, providing structural and spectral information. By spectral analysis of the backscattered light, the technique of spectroscopic-OCT enables the differentiation of structures having different spectral properties, but not the determination of their reflectance spectrum. For surface measurements, this can be achieved by applying a Fourier transform to the interferometric signals and using an accurate calibration of the optical system. An extension of this method is reported for local spectroscopic characterization of transparent samples and in particular for the determination of depth-resolved reflectance spectra of buried interfaces. The correct functioning of the method is demonstrated by comparing the results with those obtained using a program based on electromagnetic matrix methods for stratified media. Experimental measurements of spatial resolutions are provided to demonstrate the smallest structures that can be characterized

Does menopause transition influence viral suppression and adherence in Women living with HIV?

BACKGROUND Increasing numbers of women living with HIV transition through menopause. It is unclear if this transition has an impact on treatment adherence, viral suppression, psychiatric comorbidities or drug use. We aimed at examining adherence and viral suppression during the perimenopausal period and explored the influence of psychiatric comorbidities and active injection drug use (IDU). SETTING Retrospective Swiss HIV Cohort Study analysis from 01/2010 to 12/2018. METHODS We explored peri- and postmenopausal trends of viral blips, low-level viremia, viral failure, adherence, psychiatric comorbidities and IDU using interrupted time series (ITS) models. RESULTS Rates of depression and psychiatric care increased during perimenopause before decreasing afterwards. Negative treatment outcomes such as viral blips, low-level viremia, viral failure and low adherence steadily declined while transitioning through menopause - this was also true for subgroups of women with depression, psychiatric treatment and active IDU. CONCLUSIONS Increased rates of depression and psychiatric care while transitioning through menopause do not result in lower rates of adherence or viral suppression in women living with HIV in Switzerland