Effects of Acute Febrile Diseases on the Periodontium of Rhesus Monkeys with Reference to Poliomyelitis

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/67269/2/10.1177_00220345510300050301.pd

Use of ASPEN in the analysis of thermodynamic cycles

In support of a number of programmatic activities of the Department of Energy (DOE) at the Idaho National Engineering Laboratory, analysis of the performance of low-temperature binary Rankine cycles for electrical power generation and estimation of the cost of the required equipment have been important technical areas for some time. In the past, these functions had been performed using separate computer programs designed for specific applications. Significant economies could be accomplished if it were possible to use a single computer program for all applications. In performing cycle analysis and cost estimation for the recovery of low-temperature thermal energy from the Advanced Test Reactor (ATR) at INEL, the ASPEN program was used, since it appeared to have the required capabilities

Tetra Detector Analysis of Membrane Proteins

Well-characterized membrane protein detergent complexes (PDC) that are pure, homogenous and stable with minimized excess detergent micelles are essential for functional assays and crystallization studies. Procedural steps to measure the mass, size, shape, homogeneity and molecular composition of PDCs and their host detergent micelle using size exclusion chromatography (SEC) with a Viscotek tetra detector array (TDA; absorbance, refractive index, light scattering and viscosity detectors) are presented. The value of starting with a quality PDC sample, the precision and accuracy of the results, and the use of a digital bench top refractometer are emphasized. An alternate and simplified purification and characterization approach using SEC with dual absorbance and refractive index detectors to optimize detergent and lipid concentration while measuring the PDC homogeneity are also described. Applications relative to purification and characterization goals are illustrated as well

Smart artefacts as affordances for awareness in distributed teams

This book examines how the computer, as we currently know it, will be replaced by a new generation of technologies, moving computing off the desktop and ultimately integrating it with real world objects and everyday environments. Computing thus becomes an inseparable part of our everyday activities while simultaneously disappearing into the background. It becomes a ubiquitous utility taking on a role similar to electricity: an enabling but invisible and pervasive medium revealing its functionality on request in an unobtrusive way and supporting people’s everyday activities. The chapters, written by members of the Steering Group of the EU-funded Disappearing Computer research initiative, address the issues and challenges in this area

Diagnosing and categorizing leprosy in live eurasian red squirrels (Sciurus vulgaris) for management, surveillance, and translocation purposes

The presence of Mycobacterium lepromatosis and Mycobacterium leprae in Eurasian red squirrel (Sciurus vulgaris, ERS) carcasses throughout the British Isles, and leprosy as a disease, have recently been reported using histological and molecular diagnostic methods. In 2016, the first longitudinal study of ERS affected by leprosy was initiated. One of the main challenges was the reliable diagnosis of leprosy in live ERS, which is important for (a) welfare and case management and (b) surveillance or pretranslocation screening efforts. We explored diagnostic methods ranging from detailed clinical assessment and informative categorization of observed lesions, thermal imaging, serology (antiphenolic glycolipid-I antibody [αPGL-I] detection) to molecular methods (polymerase chain reaction [PCR]). For PCR the ear was established as the optimal sampling site. Based on the experiences from this 2-yr study we propose an objective categorization system for clinical lesions and a diagnostic framework for the combination of the diagnostic tools we found to be effective in live ERS: clinical assessment, αPGL-I serology, and PCR. Thermal imaging did not offer additional information for leprosy diagnostics in ERS. We propose an amended definition of leprosy lesions in ERS as “skin areas of local hair loss, in which a firm–rubbery, glossy swelling develops, that may ulcerate” and standardized terminology for describing ERS leprosy status. The information presented forms the basis of a consistent, reliable diagnostic and reporting system for leprosy cases in ERS