Superovulation and transcervical embryo recovery in Lacaune ewes raised under tropical conditions.

This study assessed two superovulatory treatments and the feasibility of transcervical embryo recovery in Lacaune ewes. Ewes (n=23) received medroxyprogesterone acetate sponges (60mg, Progespon®, Syntex, (Prolise®, Tecnopec, São Paulo, Brazil) 24 h before sponge removal and were superovulated with 133 mg of porcine FSH i.m. (Folltropin®-V; Bioniche Animal Health, Belleville, Canada) in six decreasing doses (twice daily) at 60 h before sponge removal, under a crossover design. In conclusion, both treatments showed high variability in ovulatory response which might reduce the embryo yield average from donors. The protocol for cervical relaxation allowed the transcervical embryo recovery in high percentage of Lacaune ewes

Atrial fibrillation history impact on catheter ablation outcome. Findings from the ESC-EHRA Atrial Fibrillation Ablation Long-Term Registry

Background Atrial fibrillation (AF) promotes atrial remodeling that in turn promotes AF perpetuation. The aim of our study is to investigate the impact of AF history length on 1-year outcome of AF catheter ablation in a cohort of patients enrolled in the Atrial Fibrillation Ablation Registry. Methods We described the real-life clinical epidemiology, therapeutic strategies, and the short- and mid-term outcomes of 1948 patients (71.9% with paroxysmal AF) undergoing AF ablation procedures, stratified according to AF history duration (= 2 years). Results The mean AF history duration was 46.2 +/- 57.4 months, 592 patients had an AF history duration = 2 years (mean 75.5 +/- 63.5 months) (P = 2 years (34.0%) (P = 0.037). AF history duration >= 2 years, overall ablation procedure duration, hypertension, and chronic kidney disease were all predictors of recurrences after the blanking period. Conclusions In this multicenter registry, performing catheter ablation in patients with an AF history >= 2 years was associated with higher rates of AF recurrences at 1 year. Since cumulative time in AF in not necessarily equivalent to AF history, its role remains to be clarified.Cardiolog