Hot topics in congenital heart disease and new insight into ventricular non-compaction

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Arrhythmia-associated risk: from cardiac arrest to stroke and dementia

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Atherosclerotic Plaque Disruption and Healing

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Pathophysiological aspects and management workflow of coronary microvascular obstruction in ST-segment elevation myocardial infarction

Restoring blood flow to ischemic but viable myocardium and reducing infarct size constitute the goals of reperfusion therapy with fibrinolytic drugs or primary percutaneous intervention in patients with ST-segment elevation myocardial infarction (STEMI). However, in a sizable proportion of patients, this intervention gains to reopen the obstructed epicardial coronary artery but does not achieve myocardial reperfusion because of coronary microvascular obstruction phenomenon (CMVO). In the last years, consistent evidence has pointed out how CMVO has a negative impact on outcome in patients with acute STEMI. Of note, most of the trials in this setting, mainly targeting reperfusion damage, have failed to show beneficial effects. In this article we provide a revision of mechanisms, diagnosis and prognosis of CMVO in acute STEMI, also pointing out the need of an integrated approach in order to prevent and treat CMVO in the different time windows of the acute event

The year in cardiology: acute coronary syndromes

There is an unmet need in the management of acute coronary syndromes (ACS). In 2019, there were a number of important papers published in the European Heart Journal and other journals that deepened our knowledge of the spectrum of ACS and their management

An Unusual Treatment of Atrial Fibrillation Percutaneous Exclusion of a Large Coronary Aneurysm

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