1,679 research outputs found
On-lattice agent-based simulation of populations of cells within the open-source chaste framework
Over the years, agent-based models have been developed that combine cell division and reinforced random walks of cells on a regular lattice, reaction-diffusion equations for nutrients and growth factors and ordinary differential equations (ODEs) for the subcellular networks regulating the cell cycle. When linked to a vascular layer, this multiple scale model framework has been applied to tumour growth and therapy. Here we report on the creation of an agent-based multiscale environment amalgamating the characteristics of these models within a Virtual Pysiological Human (VPH) Exemplar Project. This project enables re-use, integration, expansion and sharing of the model and relevant data. The agent-based and reactiondiffusion parts of the multiscale model have been implemented and are available for download as part of the latest public release of Chaste (“Cancer, Heart and Soft Tissue Environment”), (http://www.cs.ox.ac.uk/chaste/) version 3.1, part of the VPH Toolkit (http://toolkit.vph-noe.eu/). The environment functionalities are verified against the original models, in addition to extra validation of all aspects of the code. In this work, we present the details of the implementation of the agent-based environment, including the system description, the conceptual model, the development of the simulation model and the processes of verification and validation of the simulation results. We explore the potential use of the environment by presenting exemplar applications of the “what if” scenarios that can easily be studied in the environment. These examples relate to tumour growth, cellular competition for resources and tumour responses to hypoxia. We conclude our work by summarising the future steps for the expansion of the current system
Far-infrared all sky diffuse mapping with AKARI
We discuss the capability of AKARI in recovering diffuse far-infrared
emission, and examine the achieved reliability. Critical issues in making
images of diffuse emission are the transient response and long-term stability
of the far-infrared detectors. Quantitative evaluation of these characteristics
are the key to achieving sensitivity comparable to or better than that for
point sources (< 20 -- 95 MJy sr-1). We describe current activity and progress
toward the production of high quality images of the diffuse far-infrared
emission using the AKARI all-sky survey data.Comment: 4 pages, 8 figures, to appear in the Proceedings of the Conference
"AKARI, a light to illuminate the misty Universe", Fukutake Hall, The
University of Tokyo, Japan, 16-19 February 200
Reducción del consumo eléctrico debido a climatización en un salón de un edificio educativo del NEA
La sociedad actual demanda condiciones de confort que permitan desarrollar actividades con elevada productividad, en el NEA alcanzar las condiciones apropiadas de temperatura y humedad en edificios antiguos implica un excesivo consumo de energía eléctrica. Se presenta la simulación computacional mediante el software Energy Plus del comportamiento térmico de un aula del edificio de la Facultad Regional Resistencia de la Universidad Tecnológica Nacional. Se validan los resultados de la simulación con datos experimentales de temperatura interior para idénticas condiciones exteriores de radiación solar y temperatura. Se obtiene la carga térmica instantánea y la disminución potencial de consumo de energía eléctrica destinada a la climatización para diferentes casos de rehabilitación térmica del salón. Se verifica la exactitud del modelo confrontando los resultados de la simulación con los datos internos medidos en el aula. Se demuestra también la capacidad del software como herramienta para mejorar la eficiencia energética de edificios y garantizar las condiciones de confort.Today’s society demands high comfort conditions to carry out activities with high productivity, in the Argentine Northeast achieving the appropriate conditions of temperature and humidity in old buildings involves excessive power consumption. It is presented the computer simulation by the Energy Plus software about thermal behavior of a classroom in the building of the Facultad Regional Resistencia of the Universidad Tecnológica Nacional. The simulation results are validated with measured data of indoor temperature for the same exterior conditions of solar radiation and temperature. Is obtained the instantaneous thermal charge and the decrease of potential consumption of electricity for air conditioning in different cases of thermal rehabilitation. The accuracy of the model is verified by comparing the simulation results with internal data measured in the classroom. The ability of the software as a tool to improve the energy efficiency of buildings and ensure comfort conditions is also demonstrated.Tema 8: Energías renovables, modelización y simulación.Facultad de Arquitectura y Urbanism
Reducción del consumo eléctrico debido a climatización en un salón de un edificio educativo del NEA
La sociedad actual demanda condiciones de confort que permitan desarrollar actividades con elevada productividad, en el NEA alcanzar las condiciones apropiadas de temperatura y humedad en edificios antiguos implica un excesivo consumo de energía eléctrica. Se presenta la simulación computacional mediante el software Energy Plus del comportamiento térmico de un aula del edificio de la Facultad Regional Resistencia de la Universidad Tecnológica Nacional. Se validan los resultados de la simulación con datos experimentales de temperatura interior para idénticas condiciones exteriores de radiación solar y temperatura. Se obtiene la carga térmica instantánea y la disminución potencial de consumo de energía eléctrica destinada a la climatización para diferentes casos de rehabilitación térmica del salón. Se verifica la exactitud del modelo confrontando los resultados de la simulación con los datos internos medidos en el aula. Se demuestra también la capacidad del software como herramienta para mejorar la eficiencia energética de edificios y garantizar las condiciones de confort.Today’s society demands high comfort conditions to carry out activities with high productivity, in the Argentine Northeast achieving the appropriate conditions of temperature and humidity in old buildings involves excessive power consumption. It is presented the computer simulation by the Energy Plus software about thermal behavior of a classroom in the building of the Facultad Regional Resistencia of the Universidad Tecnológica Nacional. The simulation results are validated with measured data of indoor temperature for the same exterior conditions of solar radiation and temperature. Is obtained the instantaneous thermal charge and the decrease of potential consumption of electricity for air conditioning in different cases of thermal rehabilitation. The accuracy of the model is verified by comparing the simulation results with internal data measured in the classroom. The ability of the software as a tool to improve the energy efficiency of buildings and ensure comfort conditions is also demonstrated.Tema 8: Energías renovables, modelización y simulación.Facultad de Arquitectura y Urbanism
Reducción del consumo eléctrico debido a climatización en un salón de un edificio educativo del NEA
La sociedad actual demanda condiciones de confort que permitan desarrollar actividades con elevada productividad, en el NEA alcanzar las condiciones apropiadas de temperatura y humedad en edificios antiguos implica un excesivo consumo de energía eléctrica. Se presenta la simulación computacional mediante el software Energy Plus del comportamiento térmico de un aula del edificio de la Facultad Regional Resistencia de la Universidad Tecnológica Nacional. Se validan los resultados de la simulación con datos experimentales de temperatura interior para idénticas condiciones exteriores de radiación solar y temperatura. Se obtiene la carga térmica instantánea y la disminución potencial de consumo de energía eléctrica destinada a la climatización para diferentes casos de rehabilitación térmica del salón. Se verifica la exactitud del modelo confrontando los resultados de la simulación con los datos internos medidos en el aula. Se demuestra también la capacidad del software como herramienta para mejorar la eficiencia energética de edificios y garantizar las condiciones de confort.Today’s society demands high comfort conditions to carry out activities with high productivity, in the Argentine Northeast achieving the appropriate conditions of temperature and humidity in old buildings involves excessive power consumption. It is presented the computer simulation by the Energy Plus software about thermal behavior of a classroom in the building of the Facultad Regional Resistencia of the Universidad Tecnológica Nacional. The simulation results are validated with measured data of indoor temperature for the same exterior conditions of solar radiation and temperature. Is obtained the instantaneous thermal charge and the decrease of potential consumption of electricity for air conditioning in different cases of thermal rehabilitation. The accuracy of the model is verified by comparing the simulation results with internal data measured in the classroom. The ability of the software as a tool to improve the energy efficiency of buildings and ensure comfort conditions is also demonstrated.Tema 8: Energías renovables, modelización y simulación.Facultad de Arquitectura y Urbanism
The Far-Infrared Properties of Spatially Resolved AKARI Observations
We present the spatially resolved observations of IRAS sources from the
Japanese infrared astronomy satellite AKARI All-Sky Survey during the
performance verification (PV) phase of the mission. We extracted reliable point
sources matched with IRAS point source catalogue. By comparing IRAS and AKARI
fluxes, we found that the flux measurements of some IRAS sources could have
been over or underestimated and affected by the local background rather than
the global background. We also found possible candidates for new AKARI sources
and confirmed that AKARI observations resolved IRAS sources into multiple
sources. All-Sky Survey observations are expected to verify the accuracies of
IRAS flux measurements and to find new extragalactic point sources.Comment: 11 pages, 7 figures, accepted publication in PASJ AKARI special issu
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