Production of English Vowel Contrasts in Spanish L1 Learners: A Longitudinal Study

The present study undertakes a longitudinal examination of forty postgraduate students, native Spanish speakers, during their first year at a UK university. The research focuses on both individual and collective progress in mastering distinctions within English vowel pairs (/iː/-/ɪ/, /ɪ/-/e/, and /uː/-/ʊ/), with a specific focus on adaptations towards achieving native-like English vowel pronunciation, particularly in terms of vowel quality. Prior research indicates that adult Spanish learners encounter difficulties in mastering the intricate linguistic nuances presented by English. The methodology involved recording Spanish-speaking participants reading a list of words (CVC context) at three different time points over a year. The analysis was based on formant frequencies using Praat, and Euclidean distances were calculated to represent the degree of separation between each pair of vowels. Information about external factors potentially influencing the development of vowel productions among speakers was gathered through a language background questionnaire. The outcomes suggested varying rates of advancement within the group, which could be attributed to the diverse levels of exposure and interaction with native English speakers during their year of study in the UK. These results affirm the learning processes in adult L2 production, emphasizing the critical role played by both the quantity and quality of time in the assimilation of pronunciations to novel L2 segments

Um Interior Vazio: A análise da situação dos municípios do COREDE Fronteira Noroeste

Um dos fatores que influenciam o desenvolvimento local é a dinâmica populacional. O deslocamento de pessoas para uma determinada área está relacionado com o comportamento da economia e, a análise das conexões entre migração e desenvolvimento se torna pertinente. O Conselho Regional de Desenvolvimento (COREDE) Fronteira Noroeste é o objeto desta pesquisa devido à evasão populacional que se verifica em seu território, sobretudo nos municípios de menor porte. Esta investigação busca despertar uma reflexão sobre as causas e as soluções para este problema de modo que, o aprofundamento deste estudo contribui para o entendimento dos movimentos migratórios e o desenvolvimento. One of the factors that influence local development is the population dynamics. The movement of people to a particular area is related to the behavior of the economy and the analysis of the links between migration and development becomes relevant. The Regional Development Council (COREDE) North West Frontier is the object of this research due to the decline in population that occurs in its territory, particularly in smaller municipalities. This research seeks to arouse a reflection on the causes and solutions to this problem so that the deepening of this study contributes to the understanding of migration and development

Genomic analysis of two phlebotomine sand fly vectors of Leishmania from the New and Old World.

Phlebotomine sand flies are of global significance as important vectors of human disease, transmitting bacterial, viral, and protozoan pathogens, including the kinetoplastid parasites of the genus Leishmania, the causative agents of devastating diseases collectively termed leishmaniasis. More than 40 pathogenic Leishmania species are transmitted to humans by approximately 35 sand fly species in 98 countries with hundreds of millions of people at risk around the world. No approved efficacious vaccine exists for leishmaniasis and available therapeutic drugs are either toxic and/or expensive, or the parasites are becoming resistant to the more recently developed drugs. Therefore, sand fly and/or reservoir control are currently the most effective strategies to break transmission. To better understand the biology of sand flies, including the mechanisms involved in their vectorial capacity, insecticide resistance, and population structures we sequenced the genomes of two geographically widespread and important sand fly vector species: Phlebotomus papatasi, a vector of Leishmania parasites that cause cutaneous leishmaniasis, (distributed in Europe, the Middle East and North Africa) and Lutzomyia longipalpis, a vector of Leishmania parasites that cause visceral leishmaniasis (distributed across Central and South America). We categorized and curated genes involved in processes important to their roles as disease vectors, including chemosensation, blood feeding, circadian rhythm, immunity, and detoxification, as well as mobile genetic elements. We also defined gene orthology and observed micro-synteny among the genomes. Finally, we present the genetic diversity and population structure of these species in their respective geographical areas. These genomes will be a foundation on which to base future efforts to prevent vector-borne transmission of Leishmania parasites

AVASUS’ Contributions to Promoting Lifelong Learning in Health: Toward Achieving the SDGs and Strengthening Global Health Security

The Virtual Learning Environment of the Brazilian Health System (AVASUS) was developed by the Laboratory for Technological Innovation in Health (LAIS) and the Secretariat of Distance Education (SEDIS) at the Federal University of Rio Grande do Norte (UFRN) in partnership with Brazil’s Ministry of Health (MoH). AVASUS provides open educational resources in the health field and has emerged as the third largest platform for massive health education globally, with more than one million students. Among the various learning pathways AVASUS offers, some specifically focus on meeting the educational needs to address public health emergencies and overlooked health contexts. The main argument in this study is that technology-mediated lifelong learning in health is an effective strategy for achieving the Sustainable Development Goals (SDGs) of the 2030 Agenda. This chapter analyzes the pathways related to COVID-19, syphilis, and prison health, focusing on the contributions towards achieving SDGs 3, 4, 5, 10, 11, 16, and 17 and fulfilling the Global Health Security Agenda. Our analysis revealed two key findings. Lifelong learning in health (i) prompts decision-making on public health policies and (ii) contributes towards implementing the SDGs. Ultimately, AVASUS should be recognized as a tool to improve health services and support policy-making