118 research outputs found

    Il nuovo disegno del sistema locale

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    Il contributo passa in rassegna le previsioni contenute nel disegno di riforma costituzionale in materia di enti locali

    La Corte, l'Italicum e gli altri (il Presidente della Repubblica, il Parlamento, il Governo)

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    Il contributo commenta le ordinanze di rimessione relative alla legge elettorale cosiddetta Italicum, soprattutto sotto il profilo del criterio della rilevanza, alla luce della precedente sentenza della Corte n. 1/2014 sempre in materia di sistema elettorale

    Elezioni amministrative: con un occhio ai Comuni e due alla riforma elettorale. Una ulteriore spinta verso il proporzionale?

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    Sommario: 1. L\u2019accelerazione verso una (necessaria) modifica delle leggi elettorali.2.Il (magro) antipasto delle amministrative.3.La composizione dell\u2019offerta elettorale: quattro punti di osservazione per comprendere dove vanno i partiti (prima di vedere dove vanno gli elettori). 3.1Il Pd e \u201ca sinistra del PD\u201d. 3.2Il MoVimento 5 Stelle.3.3La coalizione di centrodestra.3.4Le formazioni centriste.4.Una riflessione conclusiva

    The Human Phenotype Ontology in 2024: phenotypes around the world

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    \ua9 The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research. The Human Phenotype Ontology (HPO) is a widely used resource that comprehensively organizes and defines the phenotypic features of human disease, enabling computational inference and supporting genomic and phenotypic analyses through semantic similarity and machine learning algorithms. The HPO has widespread applications in clinical diagnostics and translational research, including genomic diagnostics, gene-disease discovery, and cohort analytics. In recent years, groups around the world have developed translations of the HPO from English to other languages, and the HPO browser has been internationalized, allowing users to view HPO term labels and in many cases synonyms and definitions in ten languages in addition to English. Since our last report, a total of 2239 new HPO terms and 49235 new HPO annotations were developed, many in collaboration with external groups in the fields of psychiatry, arthrogryposis, immunology and cardiology. The Medical Action Ontology (MAxO) is a new effort to model treatments and other measures taken for clinical management. Finally, the HPO consortium is contributing to efforts to integrate the HPO and the GA4GH Phenopacket Schema into electronic health records (EHRs) with the goal of more standardized and computable integration of rare disease data in EHRs

    The Human Phenotype Ontology in 2024: phenotypes around the world.

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    The Human Phenotype Ontology (HPO) is a widely used resource that comprehensively organizes and defines the phenotypic features of human disease, enabling computational inference and supporting genomic and phenotypic analyses through semantic similarity and machine learning algorithms. The HPO has widespread applications in clinical diagnostics and translational research, including genomic diagnostics, gene-disease discovery, and cohort analytics. In recent years, groups around the world have developed translations of the HPO from English to other languages, and the HPO browser has been internationalized, allowing users to view HPO term labels and in many cases synonyms and definitions in ten languages in addition to English. Since our last report, a total of 2239 new HPO terms and 49235 new HPO annotations were developed, many in collaboration with external groups in the fields of psychiatry, arthrogryposis, immunology and cardiology. The Medical Action Ontology (MAxO) is a new effort to model treatments and other measures taken for clinical management. Finally, the HPO consortium is contributing to efforts to integrate the HPO and the GA4GH Phenopacket Schema into electronic health records (EHRs) with the goal of more standardized and computable integration of rare disease data in EHRs

    Il caos normativo in materia di province

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    Il caos normativo in materia di province

    La Provincia: storia istituzionale dell'ente locale più discusso. Dalla riforma di Crispi all'Assemblea Costituente

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    Fin dal suo famoso discorso di Stradella, Agostino Depretis - quale esponente principale di quella compagine di governo che avrebbe compiuto la cosiddetta “rivoluzione parlamentare” del 18761 – aveva individuato nella questione amministrativa uno dei punti cardine del programma della Sinistra
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