Extradigital glomus tumour causing thigh pain: a case report

Glomus tumours are rare and benign, arising from a neuromyoarterial glomus body, most commonly in the hand. We report a patient with such a tumour in an atypical site, the right vastus lateralis. Pain was aggravated by muscle contraction, and ultrasonography and MRI were required to locate the lesion accurately. Surgical excision gave immediate pain relief

Histomorphometric study of growth plate subjected to different mechanical conditions (compression, tension and neutralization): an experimental study in lambs. Mechanical growth plate behavior

We studied the morphologic effect of low mechanical stresses (compression, tension and neutralization) on the growth cartilage with an external fixator in 18 young lambs. On radiography, we only found more length in the femora subjected to tension (P < 0.05). Bony bridges were not present, nor were there signs of altered vascularization or Ranvier's perichondral ring. Histomorphometrically, in the group subjected to tension, the germinative layer in the femur was higher (P < 0.001) in the bones that had undergone surgery. The proliferative layer was lower in the operated tibia (P < 0.001), and the hypertrophic layer was higher in operated tibias and femora (P < 0.001). In the group subjected to compression, the germinative layer in the femora was higher in the operated bones (P < 0.05); the proliferative layer of the tibia was lower (P < 0.001) and the hypertrophic layer was higher (P < 0.001) in both operated bones. In the neutralization group, the proliferative layer of both operated bones presented lower values (P < 0.001) and the hypertrophic layer was higher (P < 0.001) than that in the control group

Empleo de aloinjerto óseo en la reparación quirúrgica de fracturas del platillo tibial

Cada vez es mayor el número de indicaciones posibles en el uso de aloinjertos en patología osteoarticular. Muchas veces supone una alternativa válida frente al uso de autoinjerto, evitando así la morbilidad que conlleva la extracción del injerto del propio paciente. Presentamos 6 casos de frac tura de platillo tibial externo en las que existía depresión central y hundimiento de la superficie articular (tipo B3 según la clasificación AO) en cuyo tratamiento quirúrgico se ha utilizado el injerto óseo de banco (fragmento de cabeza femoral tallada a medida) para el soporte del platillo tibial deprimido una vez levantado y conseguida la congruencia articular. En todos los casos se obtuvo un resultado satisfactorio en cuanto a la función de soporte y a la consolidación sin existir complicaciones per o postoperatorias

Low Energy Chiral Lagrangian in Curved Space-Time from the Spectral Quark Model

We analyze the recently proposed Spectral Quark Model in the light of Chiral Perturbation Theory in curved space-time. In particular, we calculate the chiral coefficients $L_1, ..., L_{10}$, as well as the coefficients $L_{11}$, $L_{12}$, and $L_{13}$, appearing when the model is coupled to gravity. The analysis is carried for the SU(3) case. We analyze the pattern of chiral symmetry breaking as well as elaborate on the fulfillment of anomalies. Matching the model results to resonance meson exchange yields the relation between the masses of the scalar, tensor and vector mesons, $M_{f_0}=M_{f_2}=\sqrt{2} M_V= 4 \sqrt{3 /N_c} \pi f_\pi$. Finally, the large-$N_c$ limit suggests the dual relations in the vector and scalar channels, $M_V=M_S= 2 \sqrt{6 /N_c} \pi f_\pi$ and $^{1/2}_S = < r^2 >^{1/2}_V = 2 \sqrt{N_c} / f_\pi = 0.59 {\rm fm}$.Comment: 18 pages, no figure

Analytical approach to chiral symmetry breaking in Minkowsky space

The mass gap equation for spontaneous chiral symmetry breaking is studied directly in Minkowsky space. In hadronic physics, spontaneous chiral symmetry breaking is crucial to generate a constituent mass for the quarks, and to produce the Partially Conserved Axial Current theorems, including a small mass for the pion. Here a class of finite kernels is used, expanded in Yukawa interactions. The Schwinger-Dyson equation is solved with an analytical approach. This improves the state of the art of solving the mass gap equation, which is usually solved with the equal-time approximation or with the Euclidean approximation. The mapping from the Euclidean space to the Minkowsky space is also illustrated.Comment: 7 pages, 3 figure

X chromosome inactivation does not necessarily determine the severity of the phenotype in Rett syndrome patients

Rett syndrome (RTT) is a severe neurological disorder usually caused by mutations in the MECP2 gene. Since the MECP2 gene is located on the X chromosome, X chromosome inactivation (XCI) could play a role in the wide range of phenotypic variation of RTT patients; however, classical methylation-based protocols to evaluate XCI could not determine whether the preferentially inactivated X chromosome carried the mutant or the wild-type allele. Therefore, we developed an allele-specific methylation-based assay to evaluate methylation at the loci of several recurrent MECP2 mutations. We analyzed the XCI patterns in the blood of 174 RTT patients, but we did not find a clear correlation between XCI and the clinical presentation. We also compared XCI in blood and brain cortex samples of two patients and found differences between XCI patterns in these tissues. However, RTT mainly being a neurological disease complicates the establishment of a correlation between the XCI in blood and the clinical presentation of the patients. Furthermore, we analyzed MECP2 transcript levels and found differences from the expected levels according to XCI. Many factors other than XCI could affect the RTT phenotype, which in combination could influence the clinical presentation of RTT patients to a greater extent than slight variations in the XCI pattern

Extradigital glomus tumour causing thigh pain: a case report

Glomus tumours are rare and benign, arising from a neuromyoarterial glomus body, most commonly in the hand. We report a patient with such a tumour in an atypical site, the right vastus lateralis. Pain was aggravated by muscle contraction, and ultrasonography and MRI were required to locate the lesion accurately. Surgical excision gave immediate pain relief

Empleo de aloinjerto óseo en la reparación quirúrgica de fracturas del platillo tibial

Cada vez es mayor el número de indicaciones posibles en el uso de aloinjertos en patología osteoarticular. Muchas veces supone una alternativa válida frente al uso de autoinjerto, evitando así la morbilidad que conlleva la extracción del injerto del propio paciente. Presentamos 6 casos de frac tura de platillo tibial externo en las que existía depresión central y hundimiento de la superficie articular (tipo B3 según la clasificación AO) en cuyo tratamiento quirúrgico se ha utilizado el injerto óseo de banco (fragmento de cabeza femoral tallada a medida) para el soporte del platillo tibial deprimido una vez levantado y conseguida la congruencia articular. En todos los casos se obtuvo un resultado satisfactorio en cuanto a la función de soporte y a la consolidación sin existir complicaciones per o postoperatorias

Transient osteoporosis of the hip. Presentation of a case and literature review

We present a case of idiopathic transient osteoporosis of the hip in a 43 year-old male. The patient presented with pain in the hip and limb. Hip x ray showed osteoporosis and scintigraphy revealed a diffuse uptake in the femoral head. Magnetic resonance imaging showed decreased signal intensity on the T1 weighted images and increased signal intensity on T2 weighted images in the femoral head and neck. Blood tests were normal. Healing was achieved by restricting weight-bearing and administering calcitonin and calcium. Radiographic remineralization occurred simultaneously with clinical resolutio

Quark Schwinger-Dyson evaluation of the l(1),l(2) coefficients in the chiral Lagrangian

Using a systematic expansion of the quark-antiquark Bethe Salpeter wave functions in the relativistic quark model and working to O(P-4) in the chiral limit, we are able to derive theoretical expressions relating the coefficients of the chiral Lagrangian l(1),l(2) to the underlying quark-antiquark wave functions and interaction kernels. This is accomplished by using a novel technique based on a Ward identity for the quark-antiquark ladder kernel which greatly simplifies the required effort. Numerical evaluations are performed in two simple specific models