566 research outputs found
Techno-economic assessment of sour gas oxy-combustion water cycles for CO2 capture
Growing energy demand coupled with the threat of global warming call for investigating alternative and unconventional energy sources while reducing CO2 emissions. One of these unconventional fuels is sour gas, which consists of methane, hydrogen sulfide and carbon dioxide. Using this fuel poses many challenges because of the toxic and corrosive nature of its combustion products. A promising technology for utilizing it is oxy-fuel combustion with carbon capture and storage, including the potential of enhanced oil recovery for added economic benefits. Although methane oxy-fuel cycles have been studied in the literature, using sour gas as the fuel has not been investigated or considered. In this paper, water is used as the diluent to control the flame temperature in the combustion process, and the associated cycle type is modeled to examine its performance. As the working fluid condenses, sulfuric acid forms which causes corrosion. Therefore, either expensive acid resistant materials should be used, or a redesign of the cycle is required. These different options are explored. A cost analysis of the proposed systems is also conducted to provide preliminary estimates for the levelized cost of electricity (LCOE). The results show the acid resistance cycle with a 4.5% points increase in net efficiency over the cycle with SO[subscript x] removal. However there is nearly a 9% decrease in the cycle's LCOE for the latter case.Aspen Technology, Inc
Comparison of knowledge, attitude and practice of Urban and rural households toward iron deficiency anemia in three provinces of Iran
Background: Lack of nutritional knowledge is one of the most important reasons of nutritional problems and consequently improper practice, which can lead to several complications. This study has been designed in order to compare knowledge, attitude and practices of the urban and rural households regarding iron deficiency anemia (IDA) in Boushehr, Golestan and Sistan & Balouchestan provinces in 2004. Methods: The sampling method at household's level in each province was the single-stage cluster sampling with equal size clusters. The necessary data were gathered with a structured questionnaire and via the interviews between the questioners and the eligible people in each household. Comparison of frequency of variables between urban and rural areas were tested by chi square test. Results: A total of 2306 households were selected as overall sample size. In urban areas, people recognized iron food sources better than rural areas. Knowledge level of respondents about vulnerable group for IDA and the favorite attitude of households toward IDA were better in urban areas of Sistan & Blouchestan and Golestan provinces. In Sistan & Balouchestan and Golestan, rural households who drank tea immediately before or after meal was more than urban ones. The majority of pregnant and lactating mothers (except for rural areas of Bushehr) did not take iron supplement regularly. Less than 60 percent of children used iron drop regularly. Conclusion: Knowledge, attitude, and practice levels of households toward IDA were not acceptable. One of the best ways of improving nutritional practice is nutritional education with focus on applying available food resources
Brief communication "Landslide Early Warning System: toolbox and general concepts"
We define landslide Early Warning Systems and present practical guidelines to assist end-users with limited experience in the design of landslide Early Warning Systems (EWSs). <br><br> In particular, two flow chart-based tools coming from the results of the SafeLand project (7th Framework Program) have been created to make them as simple and general as possible and in compliance with a variety of landslide types and settings at single slope scale. We point out that it is not possible to cover all the real landslide early warning situations that might occur, therefore it will be necessary for end-users to adapt the procedure to local peculiarities of the locations where the landslide EWS will be operated
On the Acceptable Risk for Structures Subjected to Geohazards
Geohazards such as earthquakes or landslides represent a major risk to structures. In this contribution risk acceptance criteria for structures subjected to geohazards are reviewed. Especially the implementation of human safety and cost benefit considerations are discussed. Current trends in the definition of target safety criteria for structures subjected to earthquakes and landslides are presented and conclusions regarding codified criteria are drawn
An efficient annotation and gene-expression derivation tool for Illumina Solexa datasets
<p>Abstract</p> <p>Background</p> <p>The data produced by an Illumina flow cell with all eight lanes occupied, produces well over a terabyte worth of images with gigabytes of reads following sequence alignment. The ability to translate such reads into meaningful annotation is therefore of great concern and importance. Very easily, one can get flooded with such a great volume of textual, unannotated data irrespective of read quality or size. CASAVA, a optional analysis tool for Illumina sequencing experiments, enables the ability to understand INDEL detection, SNP information, and allele calling. To not only extract from such analysis, a measure of gene expression in the form of tag-counts, but furthermore to annotate such reads is therefore of significant value.</p> <p>Findings</p> <p>We developed TASE (Tag counting and Analysis of Solexa Experiments), a rapid tag-counting and annotation software tool specifically designed for Illumina CASAVA sequencing datasets. Developed in Java and deployed using jTDS JDBC driver and a SQL Server backend, TASE provides an extremely fast means of calculating gene expression through tag-counts while annotating sequenced reads with the gene's presumed function, from any given CASAVA-build. Such a build is generated for both DNA and RNA sequencing. Analysis is broken into two distinct components: DNA sequence or read concatenation, followed by tag-counting and annotation. The end result produces output containing the homology-based functional annotation and respective gene expression measure signifying how many times sequenced reads were found within the genomic ranges of functional annotations.</p> <p>Conclusions</p> <p>TASE is a powerful tool to facilitate the process of annotating a given Illumina Solexa sequencing dataset. Our results indicate that both homology-based annotation and tag-count analysis are achieved in very efficient times, providing researchers to delve deep in a given CASAVA-build and maximize information extraction from a sequencing dataset. TASE is specially designed to translate sequence data in a CASAVA-build into functional annotations while producing corresponding gene expression measurements. Achieving such analysis is executed in an ultrafast and highly efficient manner, whether the analysis be a single-read or paired-end sequencing experiment. TASE is a user-friendly and freely available application, allowing rapid analysis and annotation of any given Illumina Solexa sequencing dataset with ease.</p
Hydrometeorological threshold conditions for debris flow initiation in Norway
Debris flows, triggered by extreme precipitation events and rapid snow melt, cause considerable damage to the Norwegian infrastructure every year. To define intensity-duration (ID) thresholds for debris flow initiation critical water supply conditions arising from intensive rainfall or snow melt were assessed on the basis of daily hydro-meteorological information for 502 documented debris flow events. Two threshold types were computed: one based on absolute ID relationships and one using ID relationships normalized by the local precipitation day normal (PDN). For each threshold type, minimum, medium and maximum threshold values were defined by fitting power law curves along the 10th, 50th and 90th percentiles of the data population. Depending on the duration of the event, the absolute threshold intensities needed for debris flow initiation vary between 15 and 107 mm day<sup>−1</sup>. Since the PDN changes locally, the normalized thresholds show spatial variations. Depending on location, duration and threshold level, the normalized threshold intensities vary between 6 and 250 mm day<sup>−1</sup>. The thresholds obtained were used for a frequency analysis of over-threshold events giving an estimation of the exceedance probability and thus potential for debris flow events in different parts of Norway. The absolute thresholds are most often exceeded along the west coast, while the normalized thresholds are most frequently exceeded on the west-facing slopes of the Norwegian mountain ranges. The minimum thresholds derived in this study are in the range of other thresholds obtained for regions with a climate comparable to Norway. Statistics reveal that the normalized threshold is more reliable than the absolute threshold as the former shows no spatial clustering of debris flows related to water supply events captured by the threshold
Ascaris suum: cDNA microarray analysis of 4th stage larvae (L4) during self-cure from the intestine
There is spontaneous cure of a large portion of Ascaris suum 4th-stage larvae (L4) from the jejunum of infected pigs between 14 and 21 days after inoculation (DAI). Those L4 that remain in the jejunum continue to develop while those that have moved to the ileum are eventually expelled from the intestines. Although increases in intestinal mucosal mast cells and changes in localhost immunity are coincidental with spontaneous cure, the population of L4 that continue to develop in the jejunum may counteract host protective mechanisms by the differential production of factors related to parasitism. To this end, a cDNA library was constructed from L4 isolated from pig jejunum at 21 DAI, and 93% of 1920 original clones containing a single amplicon in the range 400– 1500 bp were verified by gel electrophoresis and printed onto glass slides for microarray analysis. Fluorescent probes were prepared from total RNA isolated from: (1) 3rd stage-larvae from lung at 7 DAI, (L3); (2) L4 from jejunum at 14 DAI (L4-14-J); (3) L4 from jejunum at 21 DAI (L4-21-J); (4) L4 from ileum at 21 DAI (L4-21-I, and; (5) adults (L5). Cy3-labeled L3, L4-14-J, L4-21-I and L5 cDNA, and Cy5-labeled L4-21-J cDNA were simultaneously used to screen the printed arrays containing the L4-21-J-derived cDNA library. Several clones showed consistent differential gene expression over two separate experiments and were grouped into 3 distinct transcription patterns. The data showed that sequences from muscle actin and myosin, ribosomal protein L11, glyceraldehyde-3- phosphate dehydrogenase and the flavoprotein subunit of succinate dehydrogenase were highly expressed in L4-21-J, but not in L4- 21-I; as were a collection of unannotated genes derived from a worm body wall-hypodermis library, and a testes germinal zone tissue library. These results suggest that only actively developing A. suum L4 are destined to parasitize the host and successfully neutralize host protective responses
MAPT and PAICE: Tools for time series and single time point transcriptionist visualization and knowledge discovery
With the advent of next-generation sequencing, -omics fields such as transcriptomics have experienced increases in data
throughput on the order of magnitudes. In terms of analyzing and visually representing these huge datasets, an intuitive and
computationally tractable approach is to map quantified transcript expression onto biochemical pathways while employing datamining
and visualization principles to accelerate knowledge discovery. We present two cross-platform tools: MAPT (Mapping and
Analysis of Pathways through Time) and PAICE (Pathway Analysis and Integrated Coloring of Experiments), an easy to use
analysis suite to facilitate time series and single time point transcriptomics analysis. In unison, MAPT and PAICE serve as a visual
workbench for transcriptomics knowledge discovery, data-mining and functional annotation. Both PAICE and MAPT are two
distinct but yet inextricably linked tools. The former is specifically designed to map EC accessions onto KEGG pathways while
handling multiple gene copies, detection-call analysis, as well as UN/annotated EC accessions lacking quantifiable expression. The
latter tool integrates PAICE datasets to drive visualization, annotation, and data-mining
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