Energy and technological refurbishment of the School of Architecture Valle Giulia, Rome

Modern architecture built in historical urban contexts represents a demanding issue when its energy efficiency should be improved. Indeed, the strongest efforts have to be made to maintain the architectural identity and its harmony with the surrounding cultural heritage. This study deals with the main building of the School of Architecture Valle Giulia in Rome, designed by Enrico Del Debbio in the 30’s. Further constraints are related to several interventions of airspace expansion starting from 1958 which involved the building starting from 1958. So, preservation would mean highlighting its historic change but, adapting the built environment to the contemporary users’ needs. As above-mentioned, the building belongs to the Valle delle Accademie, within the historic park of Villa Borghese, so that to acquire landscaping values. Those latter ones call for ulterior requirements when any new design process is conceived. The study provides a global renewal of the building accounting for the current low Indoor Environmental Quality in both summer and winter seasons and the lack of suitability to the contemporary University student’s needs. The interaction between building performance and HVAC systems was studied by collecting data and architectural surveys conducted by all the architects who modified the building. This procedure was chosen since thermo-physical investigations are considered destructive due to required perforations to identify the actual wall layers. Moreover, thermographic surveys were carried out to validate the modelled building response. The result of the study is the identification of viable interventions to improve the accessibility and fruition of the building as well as its energy performance. A specific cost-benefit analysis was done to prioritize the design options along with considering the measures needed to preserve all the architectural features and values

Improvement of heart rate recovery after exercise training in older people.

Twenty-four subjects aged 70 and older were retrospectively selected from our archives and screened for symptoms of cardiovascular disease. Baseline exercise test was negative for myocardial ischemia in all subjects. All subjects had completed an 8-week program, performed for a variety of indications and consisting of an aerobic physical training program including 30 minutes of cycling three times per week at 65% to 75% of maximum heart rate achieved at peak exercise test performed at enrollment, an educational intervention, dietary advice, and psychological support. All subjects underwent a cardiopulmonary exercise test (CPX) before and at the end of exercise training. At the end of each CPX, peak oxygen uptake (VO2peak), the rate of increase of ventilation per unit of increase of carbon dioxide production (VE/VCO2slope), and HRR were recorded. Twenty-five healthy subjects younger than 60 with no evidence of exercise-induced myocardial ischemia and not enrolled in any exercise training program were also retrospectively selected from our archives and used as a control group for analyzing HRR. These patients performed two exercise tests several weeks apart. Several studies have shown that changes in vagal tone can be used as an outcome tool that helps identify patients or subjects with or without cardiovascular disease at risk for a cardiovascular event, although the evidence of a prognostic value of HRR in older subjects without cardiovascular disease is rather poor. In this study, exercise training resulted in HRR improvement in healthy elderly subjects, suggesting that exercise training improves vagal/sympathetic balance in older subjects without cardiovascular disease as well. Whether the observed improvement in HRR may have long-term beneficial prognostic effects was not the aim of the study, although a beneficial effect might be postulated, in light of the Framingham dat

Overview of the geochemical modeling on CO2 capture & storage in Italian feasibility studies

CO2 Capture & Storage in saline aquifers is presently one of the most promising technologies for reducing anthropogenic emissions of CO2. In these sites the short-longterm consequences of CO2 storage into a deep reservoir can be predicted by numerical modelling of geochemical processes. Unfortunately a common problem working with off-shore closed wells, where only the well-log information are available, is to obtain physico-chemical data (e.g. petrophysical and mineralogical) needed to reliable numerical simulations. Available site-specific data generally include only basic physical parameters such as temperature, pressure, and salinity of the formation waters. In this study we present a methodological procedure that allows to estimate and integrate lacking information to geochemical modelling of deep reservoirs such as: i) bulk and modal mineralogical composition, ii) porosity and permeability of the rock obtained from heat flow measurements and temperature, iii) chemical composition of formation waters (at reservoir conditions) prior of CO2 injection starting from sampling of analogue outcropping rock formations. The data sets in this way reconstructed constitute the base of geochemical simulations applied on some deep-seated Italian carbonatic and sandy saline aquifers potentially suitable for geological CO2 storage. Numerical simulations of reactive transport has been performed by using the reactive transport code TOUGHREACT via pressure corrections to the default thermodynamic database to obtain a more realistic modelling. Preliminary results of geochemical trapping (solubility and mineral trapping) potentiality and cap-rock stability as strategic need for some feasibility studies near to be started in Italy are here presented and discussed

A comparison between standard and crossfeed monopulse radars in presence of rough sea scattering and ship movements

Monopulse radars are widely used in tracking systems, due to their relative simplicity and theoretical precision, but the presence of multipath impairs the tracking capabilities of these radars, especially when multipath signals are strong, as in a naval environment. A special monopulse setup, the crossfeed, has been proposed in the past to provide an automatic cancellation from smooth sea multipath. In this contribution, the performances of such a system are analyzed in presence of rough sea scattering and compared with those of a standard monopulse setup. Particular attention is devoted to performance degradations due to possible phase errors in the passive network implementing the comparator and due to ship rolling and pitching. This latter requires a full 3D monopulse simulator for its correct evaluation

Prevalence and pharmacologic management of familial hypercholesterolemia in an unselected contemporary cohort of patients with stable coronary artery disease

INTRODUCTION: Familial hypercholesterolemia (FH) is an inherited disorder characterized by elevated plasma levels of low-density lipoprotein cholesterol (LDL-C) associated with premature cardiovascular disease. METHODS: Using the data from the START (STable Coronary Artery Diseases RegisTry) study, a nationwide, prospective survey on patients with stable coronary artery disease (CAD), we described prevalence and lipid lowering strategies commonly employed in these patients. The study population was divided into "definite/probable FH," defined as a Dutch Lipid Clinic Network (DLCN) score ≥6, "possible FH" with DLCN 3-5, and "unlikely FH" in presence of a DLCN <3. RESULTS: Among the 4030 patients with the DLCN score available, 132 (3.3%) were classified as FH (2.3% with definite/probable and 1.0% with possible FH) and 3898 (96.7%) had unlikely FH. Patients with both definite/probable and possible FH were younger compared to patients not presenting FH. Mean on-treatment LDL-C levels were 107.8 ± 41.5, 84.4 ± 40.9, and 85.8 ± 32.3 (P < 0.0001) and a target of ≤70 mg/dL was reached in 10.9%, 30.0%, and 22.0% (P < 0.0001) of patents with definite/probable, possible FH, and unlikely FH, respectively. Statin therapy was prescribed in 85 (92.4%) patients with definite/probable FH, in 38 (95.0%) with possible FH, and in 3621 (92.9%) with unlikely FH (P = 0.86). The association of statin and ezetimibe, in absence of other lipid-lowering therapy, was more frequently used in patients with definite/probable FH compared to patients without FH (31.5% vs 17.5% vs 9.5%; P < 0.0001). CONCLUSIONS: In this large cohort of consecutive patients with stable CAD, FH was highly prevalent and generally undertreated with lipid lowering therapies

Oleogelation of extra virgin olive oil by different gelators affects lipid digestion and polyphenol bioaccessibility

The possibility to steer extra virgin olive oil (EVOO) digestion and polyphenol bioaccessibility through oleogelation was investigated. EVOO was converted into oleogels using lipophilic (monoglycerides, rice wax, sunflower wax, phytosterols) or hydrophilic (whey protein aerogel particles, WP) gelators. In-vitro digestion demonstrated that the oleogelator nature influenced both lipid digestion and polyphenol bioaccessibility. WP-based oleogels presented ∼100% free fatty acid release compared to ∼64% for unstructured EVOO and ∼40 to ∼55% for lipophilic-based oleogels. This behavior was attributed to the ability of WP to promote micelle formation through oleogel destructuring. Contrarily, the lower lipolysis of EVOO gelled with lipophilic gelators compared to unstructured EVOO suggested that the gelator obstructed lipase accessibility. Tyrosol and hydroxytyrosol bioaccessibility increased for WP oleogels (∼27%), while liposoluble-based oleogels reduced it by 7 to 13%. These findings highlight the deep effect of the gelator choice on the digestion fate of EVOO components in the human body

Weak localization and dimensional crossover in carbon nanotube systems

We investigate the effects of magnetic and electric fields on electron wavefunction interactions in single walled carbon nanotube bundles. The magnetoresistance measurements performed at 4.2 K and the dependence of the data upon the electric field reveal good agreement with weak localization theory. An electrical field conditioned characteristic length is associated to ohmic-non ohmic transition, observed below 85 K, in current voltage characteristics. This length results equal to the average bundles diameter just at T ≅ 85 K, indicating that 2D-3D crossover is responsible for the observed conductance transition

Macroscopic Effects of Tunnelling Barriers in Aggregates of Carbon Nanotube Bundles

Abstract We report on experiments conducted on single-walled carbon nanotube bundles aligned in chains and connected through a natural contact barrier. The dependence upon the temperature of the transport properties is investigated for samples having different characteristics. Starting from two bundles separated by one barrier deposited over four-contact probes, we extend the study of the transport properties to samples formed by chains of several bundles. The systematic analysis of the properties of these aggregates shows the existence of two conduction regimes in the barrier. We show that an electrical circuit taking into account serial and parallel combinations of voltages generated at the junctions between bundles can model the samples consistently.</jats:p

Charge-transport and tunneling in single-walled carbon nanotubes

We investigate experimentally the transport properties of single-walled carbon nanotube bundles as a function of temperature and applied current over broad intervals of these variables. The analysis is performed on arrays of nanotube bundles whose axes are aligned along the direction of the externally supplied bias current. The data are found consistent with a charge transport model governed by the tunnelling between metallic regions occurring through potential barriers generated by nanotubes contact areas or bundles surfaces. Based on this model and on experimental data we describe quantitatively the dependencies of the amplitude of these barriers upon bias current and temperature.Comment: 8 pages, 4 figures. Physical Review Letters (in press