7,124 research outputs found
Discovery of a Spin-Down State Change in the LMC Pulsar B0540-69
We report the discovery of a large, sudden, and persistent increase in the
spin-down rate of B0540-69, a young pulsar in the Large Magellanic Cloud, using
observations from the Swift and RXTE satellites. The relative increase in the
spin-down rate of 36% is unprecedented for B0540-69. No accompanying change in
the spin rate is seen, and no change is seen in the pulsed X-ray emission from
B0540-69 following the change in the spin-down rate. Such large relative
changes in the spin-down rate are seen in the recently discovered class of
'intermittent pulsars', and we compare the properties of B0540-69 to such
pulsars. We consider possible changes in the magnetosphere of the pulsar that
could cause such a large change in the spin-down rate.Comment: 6 pages, 2 figures, accepted for publication in ApJ Letter
High Energy Neutrinos and Photons from Curvature Pions in Magnetars
We discuss the relevance of the curvature radiation of pions in strongly
magnetized pulsars or magnetars, and their implications for the production of
TeV energy neutrinos detectable by cubic kilometer scale detectors, as well as
high energy photons.Comment: 19 pages, 4 figures, to appear in JCA
Use of strategies to improve retention in primary care randomised trials: a qualitative study with in-depth interviews
Objective To explore the strategies used to improve retention in primary care randomised trials.<p></p>
Design Qualitative in-depth interviews and thematic analysis.<p></p>
Participants 29 UK primary care chief and principal investigators, trial managers and research nurses.<p></p>
Methods In-depth face-to-face interviews.<p></p>
Results Primary care researchers use incentive and communication strategies to improve retention in trials, but were unsure of their effect. Small monetary incentives were used to increase response to postal questionnaires. Non-monetary incentives were used although there was scepticism about the impact of these on retention. Nurses routinely used telephone communication to encourage participants to return for trial follow-up. Trial managers used first class post, shorter questionnaires and improved questionnaire designs with the aim of improving questionnaire response. Interviewees thought an open trial design could lead to biased results and were negative about using behavioural strategies to improve retention. There was consensus among the interviewees that effective communication and rapport with participants, participant altruism, respect for participant's time, flexibility of trial personnel and appointment schedules and trial information improve retention. Interviewees noted particular challenges with retention in mental health trials and those involving teenagers.<p></p>
Conclusions The findings of this qualitative study have allowed us to reflect on research practice around retention and highlight a gap between such practice and current evidence. Interviewees describe acting from experience without evidence from the literature, which supports the use of small monetary incentives to improve the questionnaire response. No such evidence exists for non-monetary incentives or first class post, use of which may need reconsideration. An exploration of barriers and facilitators to retention in other research contexts may be justified.<p></p>
Antimatter spectra from a time-dependent modeling of supernova remnants
We calculate the energy spectra of cosmic rays (CR) and their secondaries
produced in a supernova remnant (SNR), taking into account the time-dependence
of the SNR shock. We model the trajectories of charged particles as a random
walk with a prescribed diffusioncoefficient, accelerating the particles at each
shock crossing. Secondary production by CRs colliding with gas is included as a
Monte Carlo process. We find that SNRs produce less antimatter than suggested
previously: The positron/electron ratio and the antiproton/proton ratio are a
few percent and few , respectively. Both ratios do not rise
with energy.Comment: 4 pages, 4 eps figures; v2: results for time-dependent magnetic field
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A new beamline for laser spin-polarization at ISOLDE
A beamline dedicated to the production of laser-polarized radioactive beams
has been constructed at ISOLDE, CERN. We present here different simulations
leading to the design and construction of the setup, as well as technical
details of the full setup and examples of the achieved polarizations for
several radioisotopes. Beamline simulations show a good transmission through
the entire line, in agreement with observations. Simulations of the induced
nuclear spin-polarization as a function of atom-laser interaction length are
presented for Na, [1] and for Ar, which is studied in this
work. Adiabatic spin rotation of the spin-polarized ensemble of atoms, and how
this influences the observed nuclear ensemble polarization, are also performed
for the same nuclei. For Ar, we show that multiple-frequency pumping
enhances the ensemble polarization by a factor 1.85, in agreement with
predictions from a rate equations model.
[1] J. Phys. G: Nucl. Part. Phys./174408400
Plasmodium Impairs Antibacterial Innate Immunity to Systemic Infections in Part Through Hemozoin-Bound Bioactive Molecules
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