130 research outputs found
Room temperature spin filtering in epitaxial cobalt-ferrite tunnel barriers
We report direct experimental evidence of room temperature spin filtering in
magnetic tunnel junctions (MTJs) containing CoFe2O4 tunnel barriers via
tunneling magnetoresistance (TMR) measurements.
Pt(111)/CoFe2O4(111)/gamma-Al2O3(111)/Co(0001) fully epitaxial MTJs were grown
in order to obtain a high quality system, capable of functioning at room
temperature. Spin polarized transport measurements reveal significant TMR
values of -18% at 2 K and -3% at 290 K. In addition, the TMR ratio follows a
unique bias voltage dependence that has been theoretically predicted to be the
signature of spin filtering in MTJs containing magnetic barriers. CoFe2O4
tunnel barriers therefore provide a model system to investigate spin filtering
in a wide range of temperatures.Comment: 6 pages, 3 figure
Experimental application of sum rules for electron energy loss magnetic chiral dichroism
We present a derivation of the orbital and spin sum rules for magnetic
circular dichroic spectra measured by electron energy loss spectroscopy in a
transmission electron microscope. These sum rules are obtained from the
differential cross section calculated for symmetric positions in the
diffraction pattern. Orbital and spin magnetic moments are expressed explicitly
in terms of experimental spectra and dynamical diffraction coefficients. We
estimate the ratio of spin to orbital magnetic moments and discuss first
experimental results for the Fe L_{2,3} edge.Comment: 11 pages, 2 figure
A new access control unit for GANIL and SPIRAL 2
International audienceFor the GANIL safety revaluation and the new project of accelerator SPIRAL 2, it was decided to replace theexisting access control system for radiological controlled areas. These areas are all cyclotron rooms and experimental areas. The existing system is centralized around VME cards. Updating is becoming very problematic. The new UGA (access control unit) will becomposed of a pair of PLC to ensure the safety of each room. It will be supplemented by a system UGB (radiological control unit) that will assure the radiological monitoring of the area concerned
Quantitative TEM imaging of the magnetostructural and phase transitions in FeRh thin film systems
Equi-atomic FeRh is a very interesting material as it undergoes a magnetostructural transition from an antiferromagnetic (AF) to a ferromagnetic (FM) phase between 75-105 °C. Its ability to present phase co-existence separated by domain walls (DWs) above room temperature provides immense potential for exploitation of their DW motion in spintronic devices. To be able to effectively control the DWs associated with AF/FM coexistence in FeRh thin films we must fully understand the magnetostructural transition and thermomagnetic behaviour of DWs at a localised scale. Here we present a transmission electron microscopy investigation of the transition in planar FeRh thin-film samples by combining differential phase contrast (DPC) magnetic imaging with in situ heating. We perform quantitative measurements from individual DWs as a function of temperature, showing that FeRh on NiAl exhibits thermomagnetic behaviour consistent with the transition from AF to FM. DPC imaging of an FeRh sample with HF-etched substrate reveals a state of AF/FM co-existence and shows the transition from AF to FM regions proceeds via nucleation of small vortex structures, which then grow by combining with newly nucleated vortex states into larger complex magnetic domains, until it is in a fully-FM state
Avaliação nutricional do grão de ervilha forrageira (Pisum sativum) em dietas para suÃnos em crescimento
MIF Participates in Toxoplasma gondii-Induced Pathology Following Oral Infection
BACKGROUND: Macrophage migration inhibitory factor (MIF) is essential for controlling parasite burden and survival in a model of systemic Toxoplasma gondii infection. Peroral T. gondii infection induces small intestine necrosis and death in susceptible hosts, and in many aspects resembles inflammatory bowel disease (IBD). Considering the critical role of MIF in the pathogenesis of IBD, we hypothesized that MIF participates in the inflammatory response induced by oral infection with T. gondii. METHODOLOGY/PRINCIPAL FINDINGS: Mif deficient (Mif(-/-)) and wild-type mice in the C57Bl/6 background were orally infected with T. gondii strain ME49. Mif(-/-) mice had reduced lethality, ileal inflammation and tissue damage despite of an increased intestinal parasite load compared to wt mice. Lack of MIF caused a reduction of TNF-α, IL-12, IFN-γ and IL-23 and an increased expression of IL-22 in ileal mucosa. Moreover, suppressed pro-inflammatory responses at the ileal mucosa observed in Mif(-/-) mice was not due to upregulation of IL-4, IL-10 or TGF-β. MIF also affected the expression of matrix metalloproteinase-9 (MMP-9) but not MMP-2 in the intestine of infected mice. Signs of systemic inflammation including the increased concentrations of inflammatory cytokines in the plasma and liver damage were less pronounced in Mif(-/-) mice compared to wild-type mice. CONCLUSION/SIGNIFICANCE: In conclusion, our data suggested that in susceptible hosts MIF controls T. gondii infection with the cost of increasing local and systemic inflammation, tissue damage and death
IL-10 from CD4+CD25−Foxp3−CD127− Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection
The outcome of malaria infection is determined, in part, by the balance of pro-inflammatory and regulatory immune responses. Failure to develop an effective pro-inflammatory response can lead to unrestricted parasite replication, whilst failure to regulate this response leads to the development of severe immunopathology. IL-10 and TGF-β are known to be important components of the regulatory response, but the cellular source of these cytokines is still unknown. Here we have examined the role of natural and adaptive regulatory T cells in the control of malaria infection and find that classical CD4+CD25hi (and Foxp3+) regulatory T cells do not significantly influence the outcome of infections with the lethal (17XL) strain of Plasmodium yoelii (PyL). In contrast, we find that adaptive IL-10-producing, CD4+ T cells (which are CD25−, Foxp3−, and CD127− and do not produce Th1, Th2, or Th17 associated cytokines) that are generated during both PyL and non-lethal P. yoelii 17X (PyNL) infections are able to down-regulate pro-inflammatory responses and impede parasite clearance. In summary, we have identified a population of induced Foxp3− regulatory (Tr1) T cells, characterised by production of IL-10 and down regulation of IL-7Rα, that modulates the inflammatory response to malaria
Desempenho e composição corporal de suÃnos alimentados com rações com baixos teores de proteÃna bruta
Experimental reinfection of BALB/c mice with different recombinant type I/III strains of Toxoplasma gondii: involvement of IFN-³ and IL-10
- …