Peculiar Motions in the Region of the Ursa Major Supercluster of Galaxies

We have investigated the peculiar motions of clusters of galaxies in the Ursa Major (UMa) supercluster and its neighborhood. Based on SDSS (Sloan Digital Sky Survey) data, we have compiled a sample of early-type galaxies and used their fundamental plane to determine the cluster distances and peculiar velocities. The samples of early-type galaxies in the central regions (within R_200) of 12 UMa clusters of galaxies, in three main subsystems of the supercluster -- the filamentary structures connecting the clusters, and in nine clusters from the nearest UMa neighborhood have similar parameters. The fairly high overdensity (3 by the galaxy number and 15 by the cluster number) suggests that the supercluster as a whole is gravitationally bound, while no significant peculiar motions have been found: the peculiar velocities do not exceed the measurement errors by more than a factor of 1.5-2. The mean random peculiar velocities of clusters and the systematic deviations from the overall Hubble expansion in the supercluster are consistent with theoretical estimates. For the possible approach of the three UMa subsystems to be confirmed, the measurement accuracy must be increased by a factor of 2-3.Comment: 21 pages, 4 tables, 7 figure

The Structure of Clusters with Bimodal Distributions of Galaxy Radial Velocities. I. A1035

The structure of the A1035 cluster of galaxies (10h32m +40d13', cz ~ 22000 km/s), which exhibits a bimodal distribution of galaxy radial velocities (\Delta V\approx 3000 km/s), is analyzed using three methods of determining the relative distances to clusters from early-type galaxies: the Kormendy relation corrected for the dependence of residuals on galaxy magnitude, the photometric plane, and the fundamental plane. We use the data obtained with the 1-m telescope of the Special Astrophysical Observatory of the Russian Academy of Sciences and SDSS (DR5) data to show that A1035 consists of two gravitationally unbound independent clusters. These clusters with the velocity dispersions of 566 km/s and 610 km/s and masses within R_200 equal to 2.7 10^14 and 3.5 10^14 M_sun, respectively, obey the Hubble law.Comment: 13 pages, 3 tables, 6 figure

Detailed Study of the Ursa Major Supercluster of Galaxies Using the 2MASS and SDSS Catalogs

We study the infrared (K_s band) properties of clusters of galaxies in the Ursa Major supercluster using data from 2MASS (Two-Micron All-Sky Survey) and SDSS (Sloan Digital Sky Survey). We identified three large filaments with mean redshifts of z = 0.051, 0.060, and 0.071. All clusters of the supercluster are located in these filaments. We determined the total K_s-band luminosities and masses for 11 clusters of galaxies within comparable physical regions (within a radius R_200 close to the virial radius) using a homogeneous method. We constructed a combined luminosity function for the supercluster in this region, which can be described by the Schechter function with the following parameters: M*_K = -24^m.50 and \alpha = -0.98. The infrared luminosities of the clusters of galaxies correlate with their masses; the M/L_K ratios of the systems increase with their masses (luminosities), with most of the Ursa Major clusters of galaxies (particularly the richer ones) closely following the relations derived previously for a large sample of clusters and groups of galaxies. The total mass-to-infrared-luminosity ratio is 52 M_{\odot}/L_{\odot} for six Abell clusters and 49 M_{\odot}/L_{\odot} for all of the clusters, except Anon2.Comment: 16 pages, 5 figure

Precise phylogenetic analysis of microbial isolates and genomes from metagenomes using PhyloPhlAn 3.0

Microbial genomes are available at an ever-increasing pace, as cultivation and sequencing become cheaper and obtaining metagenome-assembled genomes (MAGs) becomes more effective. Phylogenetic placement methods to contextualize hundreds of thousands of genomes must thus be efficiently scalable and sensitive from closely related strains to divergent phyla. We present PhyloPhlAn 3.0, an accurate, rapid, and easy-to-use method for large-scale microbial genome characterization and phylogenetic analysis at multiple levels of resolution. PhyloPhlAn 3.0 can assign genomes from isolate sequencing or MAGs to species-level genome bins built from >230,000 publically available sequences. For individual clades of interest, it reconstructs strain-level phylogenies from among the closest species using clade-specific maximally informative markers. At the other extreme of resolution, it scales to large phylogenies comprising >17,000 microbial species. Examples including Staphylococcus aureus isolates, gut metagenomes, and meta-analyses demonstrate the ability of PhyloPhlAn 3.0 to support genomic and metagenomic analyses

ЭФФЕКТИВНОСТЬ СТАЦИОНАРНОГО ЭТАПА ЛЕЧЕНИЯ БОЛЬНЫХ ТУБЕРКУЛЕЗОМ С ЛЕКАРСТВЕННОЙ УСТОЙЧИВОСТЬЮ МИКОБАКТЕРИЙ

The composition and effectiveness of the treatment of patients 159 drug-resistant TB of Mycobacterium tuberculosis. Dominated by common processes (87%), massive bacterioexcretion (74.2%) and multidrug-resistant TB. Full clinical effect achieved in 54.8% (n = 68), including 28.8% (37) by surgical methods. Изучен состав и эффективность лечения 159 больных туберкулезом с лекарственной устойчиво-стью (ЛУ) микобактерий туберкулеза, преимущественно множественной. Преобладали распро-страненные процессы (в 87%) с массивным бактериовыделением (74,2%) и с ЛУ ко всем препара-там основного ряда. Полный клинический эффект достигнут в 54,8% (у 68 больных), в том числе в 28,8% (у 37) хирургическими методами

Медико-социальные характеристики умерших в 2017-2018 гг. в стационаре больных туберкулезом (по данным Кемеровской области)

The objective of the study: to analyze the medical and social characteristics of tuberculosis cases died in hospitals of Kemerovo Region in 2017-2018 including those with HIV infectionSubjects and methods. Clinical, radiological and morphological data of 372 patients who died in in-patient units of Kemerovo Regional Clinical Phthisiopulmonary Medical Center in 2017-2018 were studied.Results. HIV infection was the major cause of death in tuberculosis patients in Kemerovo Region - in 74.7% (278 patients). Only 21.7% died of tuberculosis, and 3.6% - died of other diseases. The main clinical form of tuberculosis in patients with TB/HIV co-infection was a generalized form with lesions in multiple organs, of them, lesions of intrathoracic lymph nodes, spleen, liver, kidneys, pleura, and central nervous system were the most frequent. In patients who died of tuberculosis, the leading clinical form was fibrous cavernous tuberculosis, mainly complicated by caseous pneumonia.Цель исследования: проанализировать медико-социальные характеристики умерших в стационарах Кемеровской области в 2017-2018 гг. больных туберкулезом, в том числе с ВИЧ-инфекцией.Материалы и методы. Изучены клинико-рентгенологические и морфологические данные 372 больных, умерших в стационарных отделениях Кемеровского областного клинического фтизиопульмонологического медицинского центра в 2017-2018 гг.Результаты. Ведущей причиной летальных исходов у больных туберкулезом в Кемеровской области явилась ВИЧ-инфекция – в 74,7% (278 больных). От туберкулеза умерли лишь 21,7%, от других заболеваний ‒ 3,6%. Основной клинической формой туберкулеза у больных сочетанной инфекцией явился генерализованный процесс с поражением многих органов, наиболее часто внутригрудных лимфатических узлов, селезенки, печени, почек, плевры, центральной нервной системы. У умерших от туберкулеза ведущей клинической формой был фиброзно-кавернозный туберкулез, преимущественно осложненный казеозной пневмонией

Летальные исходы у больных туберкулезом в динамике за 17 лет в Кемеровской области

Lethal outcomes were studied in 704 tuberculosis patients in Kemerovo Region over 2 periods of time: 1995-1997 – 255 cases (including 229 with autopsy) and 2012-2014 – 449 cases (including 413 with autopsy) in three in-patient units of Kemerovo Regional Clinical TB Dispensary (continuous sampling). The number of those died during the second period increased due to co-infection of HIV and tuberculosis. During the second period there was an abrupt increase in disseminated forms of tuberculosis while the number of fibrous-cavernous forms went down, which was due to specific features of tuberculosis in HIV patients given the severe immune deficiency in them. At the same time the increase in the disseminated forms of tuberculosis was detected during the 2nd period in the HIV negative patients.Изучены летальные исходы у 704 больных туберкулезом в Кемеровской области за 2 периода: 1995-1997 гг. - 255 (в том числе вскрытых 229) и 2012-2014 гг. - 449 (в том числе вскрытых 413) в трех стационарных отделениях Кемеровского областного клинического противотуберкулезного диспансера (метод сплошной выборки). Увеличение числа умерших во II периоде произошло за счет больных ВИЧ-инфекцией в сочетании с туберкулезом. Во II периоде резко увеличилось число больных диссеминированным туберкулезом и сократилось с фиброзно-кавернозным туберкулезом, что объясняется особенностями туберкулеза у больных ВИЧ-инфекцией на фоне выраженного иммунодефицита. В то же время рост диссеминированных форм туберкулеза выявлен во II периоде и у больных туберкулезом без ВИЧ-инфекции

Tunka-Rex Virtual Observatory

Tunka-Rex (Tunka Radio Extension) was a detector for ultra-high energy cosmic rays measuring radio emission for air showers in the frequency band of 30-80 MHz, operating in 2010s. It provided an experimental proof that sparse radio arrays can be a cost-effective technique to measure the depth of shower maximum with resolutions competitive to optical detectors. After the decommissioning of Tunka-Rex, as last phase of its lifecycle and following the FAIR (Findability — Accessibility — Interoperability — Reuse) principles, we publish the data and software under free licenses in the frame of the TRVO (Tunka-Rex Virtual Observatory), which is hosted at KIT under the partnership with the KCDC and GRADLCI projects. We present the main features of TRVO, its interface and give an overview of projects, which benefit from its open software and data