924 research outputs found

    Amorphization and evolution of magnetic properties during mechanical alloying of Co62Nb6Zr2B30: Dependence on starting boron microstructure

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    Co62Nb6Zr2B30 composition was mechanically alloyed using three different types of boron powders in the starting mixture: crystalline β-B, commercial amorphous B and optimized amorphous B via ball milling. Using optimized amorphous B, amorphization process of the alloy is more efficient but milling to optimize amorphous B introduces some iron contamination. Boron inclusions (100-150 nm in size) remain even after long milling times. However, using amorphous boron reduces the fraction of boron distributed as inclusions to ∼40% of the total B. Thermal stability at the end of the milling process is affected by the initial boron microstructure. Coercivity is reduced a half using amorphous B instead of crystalline B in the starting mixture. © 2013 Elsevier B.V. All rights reserved.Peer Reviewe

    Prospecting models of primary diamond deposits of the north of the East European Platform

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    As a result of a comprehensive study of the geological structure and diamond presense of the northern part of the East European Platform, generalization of the data accumulated by various organizations in the USSR, the Russian Federation, and other states, three main prospecting models of primary diamond deposits have been identified and characterized: Karelian, Finnish, and Arkhangelsk. Geological, structural, mineralogical, and petrographic criteria of local prediction, as well as the features of the response of kimberlite and lamproite bodies in dispersion haloes and geophysical fields, are considered using known examples, including data on the developed M.V.Lomonosov and V.P.Grib mines. It is shown that the most complicated prospecting environments occur in the covered areas of the Russian Plate, where, in some cases, the primary diamond-bearing rocks are similar in their petrophysical properties to the host formations. The buried dispersion haloes of kimberlite minerals in the continental Carboniferous and Quaternary deposits are traced at a short distance from the sources. Differences in the prospecting features of magnesian (Lomonosov mine) and ferromagnesian (Grib mine) kimberlites are also shown. Conclusions about the diamond potential of the model objects of various types are given in this paper

    Current Developments in the Genetics of Autism: From Phenome to Genome

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    Despite compelling evidence from twin and family studies indicating a strong genetic involvement in the etiology of autism, the unequivocal detection of autism susceptibility genes remains an elusive goal. The purpose of this review is to evaluate the current state of autism genetics research, with attention focused on new techniques and analytic approaches. We first present a brief overview of evidence for the genetic basis of autism, followed by an appraisal of linkage and candidate gene study findings and consideration of new analytic approaches to the study of complex psychiatric conditions, namely, genome-wide association studies, assessment of structural variation within the genome, and the incorporation of endophenotypes in genetic analysis

    International capital mobility in an era of globalisation: adding a political dimension to the 'Feldstein–Horioka Puzzle'

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    The debate about the scope of feasible policy-making in an era of globalisation continues to be set within the context of an assumption that national capital markets are now perfectly integrated at the international level. However, the empirical evidence on international capital mobility contradicts such an assumption. As a consequence, a significant puzzle remains. Why is it, in a world in which the observed pattern of capital flows is indicative of a far from globalised reality, that public policy continues to be constructed in line with more extreme variants of the globalisation hypothesis? I attempt to solve this puzzle by arguing that ideas about global capital market integration have an independent causal impact on political outcomes which extends beyond that which can be attributed to the extent of their actual integration

    Potential Risk Factors for the Development of Self-Injurious Behavior among Infants at Risk for Autism Spectrum Disorder

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    Prevalence of self-injurious behavior (SIB) is as high as 50% among children with autism spectrum disorder (ASD). Identification of risk factors for the development of SIB is critical to early intervention and prevention. However, there is little empirical research utilizing a prospective design to identify early risk factors for SIB. The purpose of this study was to evaluate behavioral characteristics predicting SIB at age 2 years among 235 infants at high familial risk for ASD. Logistic regression results indicated that presence of SIB or proto-SIB and lower developmental functioning at age 12 months significantly predicted SIB at 24 months. A pattern of persistent SIB over this period was associated with a diagnosis of autism and poorer cognitive and adaptive outcomes

    New development: Running elections during a pandemic

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    The Covid-19 pandemic posed a profound challenge for the delivery of elections worldwide. Elections are indispensable for democracy, but the high volume of human interactions within the electoral process risked spreading the virus. Electoral officials therefore found themselves planning or managing an election during an emergency situation, often for the first time. This article argues that there are several major organizational ‘elephant traps’ that polities will need to side-step during pandemics in order to safely protect the healthy running of elections. IMPACT: Elections often take place in during emergency situations such as pandemics, floods, earthquakes and hurricanes. In order to secure electoral integrity, this article encourages governments, legislators and electoral management bodies to: build political consensuses, consider the impact on the whole electoral cycle, include a wide range of stakeholders in meetings, invest in sufficient resources, undertake risk assessments and avoid late major changes to electoral law

    СИНТЕЗ КОНЪЮГАТОВ ПЕНТАЦИКЛИЧЕСКИХ ТРИТЕРПЕНОВЫХ КИСЛОТ РЯДА ЛУПАНА С ПРОИЗВОДНЫМИ 6,7-ДИГИДРО-1Н-ИНДАЗОЛ-4(5Н)-ОНОВ

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    Approaches to a synthesis of new conjugates of betulonic and betulinic acids with 6,7-dihydro-1H-indazol-4(5H)-one derivatives had been developed and realized. Conjugate of betulonic acid was obtained via the acylation of 1-aryl-3-perfluoroalkyl-6,7-dihydro-1H indazol-4(5H)-one oxime with betulonic chloride. The synthesis of conjugate of betulinic acid was accomplished via the acylation of 7-amino-1-aryl-3-perfluoroalkyl-6,7-dihydro-1H indazol-4(5H)-one with 3-O-(2-chloro-2-oxoacetyl)betulinic chloride.Разработаны и реализованы подходы к синтезу конъюгатов бетулоновой и бетулиновой кислот с производными 6,7-дигидро-1Н-индазол-4(5Н)-онов. Конъюгат бетулоновой кислоты получен ацилированием оксима 1-арил-3-(перфторалкил)-6,7-дигидро-1H-индазол-4(5H)-она хлорангидридом бетулоновой кислоты. Cинтез конъюгата бетулиновой кислоты осуществлен путем ацилирования 7-амино-3-перфторалкил-1-арил-6,7-дигидро-1H-индазол-4(5H)-она хлорангидридом 3-О-(2-хлоро-2-оксоацетил)бетулиновой кислоты
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