Fabrication of quantum point contacts by engraving GaAs/AlGaAs-heterostructures with a diamond tip

We use the all-diamond tip of an atomic force microscope for the direct engraving of high quality quantum point contacts in GaAs/AlGaAs-heterostructures. The processing time is shortened by two orders of magnitude compared to standard silicon tips. Together with a reduction of the line width to below 90 nm the depletion length of insulating lines is reduced by a factor of two with the diamond probes. The such fabricated defect free ballistic constrictions show well resolved conductance plateaus and the 0.7 anomaly in electronic transport measurements.Comment: 3 pages, 3 figure

Storm hazards '79: F-106B operations summary

Preliminary flight tests with a F-106B aircraft were made on the periphery of isolated thunder cells using weather radar support. In addition to storm hazards correlation research, a direct-strike lightning measurement experiment and an atmospheric chemistry experiment were conducted. Two flights were made to close proximity to lightning generating cumulonimbus clouds; however, no direct lightning strikes were experienced. Although no discernible lightning transients were recorded, many operational techniques were identified and established

Nanopore analysis of amyloid fibrils formed by lysozyme aggregation.

The measurement of single particle size distributions of amyloid fibrils is crucial for determining mechanisms of growth and toxicity. Nanopore sensing is an attractive solution for this problem since it gives information on aggregates' shapes with relatively high throughput for a single particle technology. In this paper we study the translocation of lysozyme fibrils through quartz glass nanopores. We demonstrate that, under appropriate salt and pH conditions, lysozyme fibrils translocate through bare quartz nanopores without causing significant clogging. This enables us to measure statistics on tens of thousands of translocations of lysozyme fibrils with the same nanopore and track their development over a time course of aggregation spanning 24 h. Analysis of our events shows that the statistics are consistent with a simple bulk conductivity model for the passage of rods with a fixed cross sectional area through a conical glass nanopore.N.A.W.B. acknowledges funding from the EPSRC NanoDTC program and an EPSRC doctoral prize award and U.F.K. acknowledges funding from an ERC starting grant, PassMembrane (261101).This is the final version of the article. It first appeared from RSC via http://dx.doi.org/10.1039/C5AN00530

The use of neural network algorithms for the classification of undifferentiated arthritis by synovial histopathology

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