2,945 research outputs found
Phase diagram and magnetic properties of LaCaMnO compound for
In this article a detailed study of LaCaMnO () phase diagram using powder x-ray diffraction and magnetization
measurements is presented. Unfortunately, in the related literature no properly
characterized samples have been used, with consequence the smearing of the real
physics in this complicated system. As the present results reveal, there are
two families of samples. The first family concerns samples prepared in
atmosphere ( Atm) which are all ferromagnetic with Curie
temperature rising with . The second family concerns samples, where a post
annealing in nearly zero oxygen partial pressure is applied. These samples show
a canted antiferromagnetic structure for below , while
for an unconventional ferromagnetic insulated phase is
present below . The most important difference between nonstoichiometric
and stoichiometric samples concerning the magnetic behavior, is the anisotropy
in the exchange interactions, in the stoichiometric samples putting forward the
idea that a new orbital ordered phase is responsible for the ferromagnetic
insulating regime in the LaCaMnO compound
Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson–Gilford Progeria Syndrome
Hutchinson–Gilford progeria syndrome (HGPS) is a genetic disorder characterized by premature aging features. Cells from HGPS patients express progerin, a truncated form of Lamin A, which perturbs cellular homeostasis leading to nuclear shape alterations, genome instability, heterochromatin loss, telomere dysfunction and premature entry into cellular senescence. Recently, we reported that telomere dysfunction induces the transcription of telomeric non-coding RNAs (tncRNAs) which control the DNA damage response (DDR) at dysfunctional telomeres. Here we show that progerin-induced telomere dysfunction induces the transcription of tncRNAs. Their functional inhibition by sequence-specific telomeric antisense oligonucleotides (tASOs) prevents full DDR activation and premature cellular senescence in various HGPS cell systems, including HGPS patient fibroblasts. We also show in vivo that tASO treatment significantly enhances skin homeostasis and lifespan in a transgenic HGPS mouse model. In summary, our results demonstrate an important role for telomeric DDR activation in HGPS progeroid detrimental phenotypes in vitro and in vivo
Regulating human interventions in Colombian coastal areas: Implications for the environmental licensing procedure in middle-income countries
Although anthropogenic impacts could be assessed in any environment, coastal areas pose a particular challenge because of their special nature as the interface between land and sea. Therefore, this study evaluates the environmental regulatory framework for coastal interventions in Colombia, as an archetype of medium income countries (MICs), to derive implications for the environmental licensing procedure (ELP). The methods comprised two simultaneous pathways: a. An inventory of human interventions at the large scale area of the Colombian Caribbean Coast, with an estimation of the overall environmental impact; b. An analysis of the ELP in Colombia during the last 25 years. The study evidences several weaknesses, such as a consistent reduction in the number of works and activities covered in each new legislative. Moreover, the Colombian ELP currently regulates only four of the ten types of interventions with greater effect in its coastal zones. The discussions highlight some policy implications for the ELP in MICs, mainly based on how the impact of a type of intervention can be magnified in proportion to its frequency of occurrence, and the need to articulate instruments of environmental management and territorial planning. At last, the need to evolve the impact assessment of human interventions from environmental factors toward socio-natural processes is evidenced and further addressed, by the introduction of a susceptibility approach inspired on geomorphological processes. Overall, this study highlights important gaps of the Colombian ELP for coastal environments, which entails valuable lessons for MICs
Evidence for Jahn-Teller distortions at the antiferromagnetic transition in LaTiO
LaTiO is known as Mott-insulator which orders antiferromagnetically at
K. We report on results of thermal expansion and temperature
dependent x-ray diffraction together with measurements of the heat capacity,
electrical transport measurements, and optical spectroscopy in untwinned single
crystals. At significant structural changes appear, which are
volume conserving. Concomitant anomalies are also observed in the
dc-resistivity, in bulk modulus, and optical reflectivity spectra. We interpret
these experimental observations as evidence of orbital order.Comment: 4 pages, 4 figures; published in Phys. Rev. Lett. 91, 066403 (2003
Crystal structure and high-field magnetism of La2CuO4
Neutron diffraction was used to determine the crystal structure and magnetic
ordering pattern of a La2CuO4 single crystal, with and without applied magnetic
field. A previously unreported, subtle monoclinic distortion of the crystal
structure away from the orthorhombic space group Bmab was detected. The
distortion is also present in lightly Sr-doped crystals. A refinement of the
crystal structure shows that the deviation from orthorhombic symmetry is
predominantly determined by displacements of the apical oxygen atoms. An
in-plane magnetic field is observed to drive a continuous reorientation of the
copper spins from the orthorhombic b-axis to the c-axis, directly confirming
predictions based on prior magnetoresistance and Raman scattering experiments.
A spin-flop transition induced by a c-axis oriented field previously reported
for non-stoichiometric La2CuO4 is also observed, but the transition field (11.5
T) is significantly larger than that in the previous work
Degeneracy in excited state quantum phase transitions of two-level bosonic models and its influence on system dynamics
Excited state quantum phase transitions in collective many-body quantum
systems influence the system spectral properties due to changing degeneracy
patterns in different phases. We report a fundamental difference in the nature
of the degeneracy for boson two-level models, depending on the dimension of the
space where the models were defined. To illustrate the consequences, we assess
the validity of an out-of-time-order correlator as a possible order operator
for excited state quantum phase transitions in different models
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