947 research outputs found

    Breakdown of smoothness for the Muskat problem

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    In this paper we show that there exist analytic initial data in the stable regime for the Muskat problem such that the solution turns to the unstable regime and later breaks down i.e. no longer belongs to C4C^4.Comment: 93 pages, 10 figures (6 added

    Automation on the generation of genome scale metabolic models

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    Background: Nowadays, the reconstruction of genome scale metabolic models is a non-automatized and interactive process based on decision taking. This lengthy process usually requires a full year of one person's work in order to satisfactory collect, analyze and validate the list of all metabolic reactions present in a specific organism. In order to write this list, one manually has to go through a huge amount of genomic, metabolomic and physiological information. Currently, there is no optimal algorithm that allows one to automatically go through all this information and generate the models taking into account probabilistic criteria of unicity and completeness that a biologist would consider. Results: This work presents the automation of a methodology for the reconstruction of genome scale metabolic models for any organism. The methodology that follows is the automatized version of the steps implemented manually for the reconstruction of the genome scale metabolic model of a photosynthetic organism, {\it Synechocystis sp. PCC6803}. The steps for the reconstruction are implemented in a computational platform (COPABI) that generates the models from the probabilistic algorithms that have been developed. Conclusions: For validation of the developed algorithm robustness, the metabolic models of several organisms generated by the platform have been studied together with published models that have been manually curated. Network properties of the models like connectivity and average shortest mean path of the different models have been compared and analyzed.Comment: 24 pages, 2 figures, 2 table

    Some comments on the inverse problem of pure point diffraction

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    In a recent paper, Lenz and Moody (arXiv:1111.3617) presented a method for constructing families of real solutions to the inverse problem for a given pure point diffraction measure. Applying their technique and discussing some possible extensions, we present, in a non-technical manner, some examples of homometric structures.Comment: 6 pages, contribution to Aperiodic 201

    Rank one discrete valuations of power series fields

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    In this paper we study the rank one discrete valuations of the field k((X1,...,Xn))k((X_1,..., X_n)) whose center in k\lcor\X\rcor is the maximal ideal. In sections 2 to 6 we give a construction of a system of parametric equations describing such valuations. This amounts to finding a parameter and a field of coefficients. We devote section 2 to finding an element of value 1, that is, a parameter. The field of coefficients is the residue field of the valuation, and it is given in section 5. The constructions given in these sections are not effective in the general case, because we need either to use the Zorn's lemma or to know explicitly a section σ\sigma of the natural homomorphism R_v\to\d between the ring and the residue field of the valuation vv. However, as a consequence of this construction, in section 7, we prove that k((\X)) can be embedded into a field L((\Y)), where LL is an algebraic extension of kk and the {\em ``extended valuation'' is as close as possible to the usual order function}

    A maximum principle for the Muskat problem for fluids with different densities

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    We consider the fluid interface problem given by two incompressible fluids with different densities evolving by Darcy's law. This scenario is known as the Muskat problem for fluids with the same viscosities, being in two dimensions mathematically analogous to the two-phase Hele-Shaw cell. We prove in the stable case (the denser fluid is below) a maximum principle for the LL^\infty norm of the free boundary.Comment: 16 page
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