736 research outputs found
Factorizations of Elements in Noncommutative Rings: A Survey
We survey results on factorizations of non zero-divisors into atoms
(irreducible elements) in noncommutative rings. The point of view in this
survey is motivated by the commutative theory of non-unique factorizations.
Topics covered include unique factorization up to order and similarity, 2-firs,
and modular LCM domains, as well as UFRs and UFDs in the sense of Chatters and
Jordan and generalizations thereof. We recall arithmetical invariants for the
study of non-unique factorizations, and give transfer results for arithmetical
invariants in matrix rings, rings of triangular matrices, and classical maximal
orders as well as classical hereditary orders in central simple algebras over
global fields.Comment: 50 pages, comments welcom
Prosocial response to client-instigated victimisation: the roles of forgiveness and workgroup conflict
We investigate forgiveness as a human service employee coping response to client-instigated victimizations and further explore the role of workgroup conflict in 1) facilitating this response, and 2) influencing the relationship between victimization and workplace outcomes. Using the theoretical lens of Conservation of Resources (Hobfoll, 1989), we propose that employees forgive clients – especially in the context of low workgroup conflict. From low to moderate levels of client-instigated victimization, we suggest that victimization and forgiveness are positively related; however, this positive relationship does not prevail when individuals confront egregious levels of victimization (i.e., an inverted-U shape). This curvilinear relationship holds under low but not under high workgroup conflict. Extending this model to workplace outcomes, findings also demonstrate that the indirect effects of victimization on job satisfaction, burnout, and turnover intentions are mediated by forgiveness when workgroup conflict is low. Experiment- and field-based studies provide evidence for the theoretical model
La médiation interculturelle : une approche pour soutenir la relation parents immigrants-orthophonistes au niveau primaire
À partir de deux études (Bergeron et Beauregard, 2018 ; Borri-Anadon, 2014), l’une portant sur les parents immigrants et l’autre sur les orthophonistes travaillant en milieu scolaire multiethnique, l’article documente les perceptions de ces deux groupes quant aux pratiques de chacun à l’égard de l’enfant-élève issu de l’immigration ayant des difficultés de langage. En mobilisant le cadre théorique de l’approche interculturelle (Cohen-Emerique, 2015), les convergences et les divergences de ces perceptions sont mises en évidence. Cette mise en relation permet d’aborder la médiation interculturelle, en tant que processus de réflexion sur soi, sur l’autre et sur leurs interactions, comme étant susceptible de favoriser, par la connaissance et la reconnaissance mutuelles de leur expertise, la réussite éducative de l’enfant-élève
Prosocial response to client-instigated victimization: the roles of forgiveness and workgroup conflict
We investigate forgiveness as a human service employee coping response to client-instigated victimizations and further explore the role of workgroup conflict in 1) facilitating this response, and 2) influencing the relationship between victimization and workplace outcomes. Using the theoretical lens of Conservation of Resources (Hobfoll, 1989), we propose that employees forgive clients – especially in the context of low workgroup conflict. From low to moderate levels of client-instigated victimization, we suggest that victimization and forgiveness are positively related; however, this positive relationship does not prevail when individuals confront egregious levels of victimization (i.e., an inverted-U shape). This curvilinear relationship holds under low but not under high workgroup conflict. Extending this model to workplace outcomes, findings also demonstrate that the indirect effects of victimization on job satisfaction, burnout, and turnover intentions are mediated by forgiveness when workgroup conflict is low. Experiment- and field-based studies provide evidence for the theoretical model
Early anterior cingulate involvement is seen in presymptomatic MAPT P301L mutation carriers
BACKGROUND: PET imaging of glucose metabolism has revealed presymptomatic abnormalities in genetic FTD but has not been explored in MAPT P301L mutation carriers. This study aimed to explore the patterns of presymptomatic hypometabolism and atrophy in MAPT P301L mutation carriers. METHODS: Eighteen asymptomatic members from five families with a P301L MAPT mutation were recruited to the study, six mutation carriers, and twelve mutation-negative controls. All participants underwent standard behavioural and cognitive assessment as well as [18F]FDG-PET and 3D T1-weighted MRI brain scans. Regional standardised uptake value ratios (SUVR) for the PET scan and volumes calculated from an automated segmentation for the MRI were obtained and compared between the mutation carrier and control groups. RESULTS: The mean (standard deviation) estimated years from symptom onset was 12.5 (3.6) in the mutation carrier group with a range of 7 to 18 years. No differences in cognition were seen between the groups, and all mutation carriers had a global CDR plus NACC FTLD of 0. Significant reduction in [18F] FDG uptake in the anterior cingulate was seen in mutation carriers (mean 1.25 [standard deviation 0.07]) compared to controls (1.36 [0.09]). A similar significant reduction was also seen in grey matter volume in the anterior cingulate in mutation carriers (0.60% [0.06%]) compared to controls (0.68% [0.08%]). No other group differences were seen in other regions. CONCLUSIONS: Anterior cingulate hypometabolism and atrophy are both apparent presymptomatically in a cohort of P301L MAPT mutation carriers. Such a specific marker may prove to be helpful in stratification of presymptomatic mutation carriers in future trials
Les angles morts des travaux sur l’inclusion scolaire à la lumière de la théorie de la justice sociale de Nancy Fraser
Cet article a pour objectif d’éclairer les angles morts des travaux sur l’inclusion scolaire à la lumière de la théorie de la justice sociale de Nancy Fraser. Sur la base des paradigmes de redistribution, de reconnaissance et de représentation, il met en lumière plusieurs angles morts, tant sur le plan politique que paradigmatique. Si l’on n’en tient pas compte, ces angles morts peuvent entraîner une forme normative et prescriptive de l’inclusion à travers la simplification de la complexité du réel, et la mise en place de remèdes correctifs. Il convient donc d’adopter une approche critique de l’inclusion, qui peut être facilitée par l’utilisation de certains concepts comme le climat scolaire, la participation sociale et l’advocacy
Aspirin and some other nonsteroidal anti-inflammatory drugs inhibit cystic fibrosis transmembrane conductance regulator protein gene expression in T-84 cells.
Cystic fibrosis (CF) is caused by mutations in the CF gene, which encodes CF transmembrane conductance regulator protein (CFTR), a transmembrane protein that acts as a cAMP-regulated chloride channel The disease is characterized by inflammation but the relationship between inflammation, abnormal transepithelial ion transport, and the clinical manifestations of CF are uncertain. The present study was undertaken to determine whether three nonsteroidal anti-inflammatory drugs (NSAIDs) (aspirin, ibuprofen, and indomethacin) modulate CFTR gene expression in T-84 cells. Treatment with NSAIDs reduced CFTR transcripts, and decreased cAMP-stimulated anion fluxes, an index of CFTR function. However, the two phenomena occurred at different concentrations of both drugs. The results indicate that NSAIDs can regulate both CFTR gene expression and the function of CFTR-related chloride transport, and suggest that NSAIDs act via multiple transduction pathways
Cartan's spiral staircase in physics and, in particular, in the gauge theory of dislocations
In 1922, Cartan introduced in differential geometry, besides the Riemannian
curvature, the new concept of torsion. He visualized a homogeneous and
isotropic distribution of torsion in three dimensions (3d) by the "helical
staircase", which he constructed by starting from a 3d Euclidean space and by
defining a new connection via helical motions. We describe this geometric
procedure in detail and define the corresponding connection and the torsion.
The interdisciplinary nature of this subject is already evident from Cartan's
discussion, since he argued - but never proved - that the helical staircase
should correspond to a continuum with constant pressure and constant internal
torque. We discuss where in physics the helical staircase is realized: (i) In
the continuum mechanics of Cosserat media, (ii) in (fairly speculative) 3d
theories of gravity, namely a) in 3d Einstein-Cartan gravity - this is Cartan's
case of constant pressure and constant intrinsic torque - and b) in 3d Poincare
gauge theory with the Mielke-Baekler Lagrangian, and, eventually, (iii) in the
gauge field theory of dislocations of Lazar et al., as we prove for the first
time by arranging a suitable distribution of screw dislocations. Our main
emphasis is on the discussion of dislocation field theory.Comment: 31 pages, 8 figure
The implications of policy changes on the uptake of a PMTCT programme in rural Malawi: first three years of experience
Objective: To study how the demand for antenatal care (ANC), HIV testing and hospital delivery was influenced by policy changes among pregnant women in rural Malawi. Design: Retrospective analysis of monthly reports. Setting: Malamulo SDA hospital in Thyolo district, Makwasa, Malawi. Methods: Three hospital-based registers were analysed from 2005 to 2007. These were general ANC, delivery and Prevention of Mother to Child Transmission (PMTCT) registers. Observations were documented regarding the introduction of specific policies and when changes were effected. Descriptive analytical methods were used. Results: The ANC programme reached 4,528 pregnant mothers during the study period. HIV testing among the ANC attendees increased from 52.6 to 98.8% after the introduction of routine (opt-out) HIV testing and 15.6% of them tested positive. After the introduction of free maternity services, ANC attendance increased by 42% and the ratio of hospital deliveries to ANC attendees increased from 0.50:1 to 0.66:1. Of the HIV-tested ANC attendees, 52.6% who tested positive delivered in the hospital and got nevirapine at the time of delivery. Conclusions: Increasing maternity service availability and uptake can increase the coverage of PMTCT programmes. Barriers such as economic constraints that prevent women in poor communities from accessing services can be removed by making maternity services free. However, it is likely, particularly in resource-poor settings, that significant increases in PMTCT coverage among those at risk can only be achieved by substantially increasing uptake of general ANC and delivery services.We thank the Swedish Institute, Sweden for the financial support without which the study would have been a non-starter. We are also grateful for the support given by the unit of Epidemiology and Public Health Sciences, Umea University. Furthermore, we thank the management and staff of Malamulo SDA Hospital, P/Bag 2, Makwasa, Malawi for their support throughout the entire period of carrying out the study. This work was undertaken within the Centre for Global Health at Umea University with support from FAS, the Swedish Council for Working Life and Social Research (grant no. 2006-1512).</p
- …