Nonlinear dynamics of a cigar-shaped Bose-Einstein condensate coupled with a single cavity mode

We investigate the nonlinear dynamics of a combined system which is composed of a cigar-shaped Bose-Einstein condensate and an optical cavity. The two sides couple dispersively. This system is characterized by its nonlinearity: after integrating out the freedom of the cavity mode, the potential felt by the condensate depends on the condensate itself. We develop a discrete-mode approximation for the condensate. Based on this approximation, we map out the steady configurations of the system. It is found that due to the nonlinearity of the system, the nonlinear levels of the system can fold up in some parameter regimes. That will lead to the breakdown of adiabaticity. Analysis of the dynamical stability of the steady states indicates that the same level structure also results in optical bistability.Comment: 8 pages, 5 figure

An experimental study for a miniature Stirling refrigerator

Experimental results of a miniature two-stage Stirling cryocooler are introduced. The influence of filling gas pressure and refrigeration temperature on the refrigerating capacity along with the relationship between parameters was measured. The valley pressure corresponding to the lowest refrigeration temperature and the cooldown time versus operating pressure are discussed. The coefficient of performance and thermodynamic efficiency of the cryocooler are calculated based on experimental data

Cessation of X-ray Pulsation of GX 1+4

We report results from our weekly monitoring campaign on the X-ray pulsar GX 1+4 with the {\em Rossi X-ray Timing Explorer} satellite. The spin-down trend of GX 1+4 was continuing, with the pulsar being at its longest period ever measured (about 138.7 s). At the late stage of the campaign, the source entered an extended faint state, when its X-ray (2-60 keV) flux decreased significantly to an average level of $\sim 3 \times 10^{-10} ergs cm^{-2} s^{-1}$. It was highly variable in the faint state; the flux dropped to as low as $\sim 3 \times 10^{-11} ergs cm^{-2} s^{-1}$. In several observations during this period, the X-ray pulsation became undetectable. We can, therefore, conclude conservatively that the pulsed fraction, which is normally $\gtrsim$ 70% (peak-to-peak), must have decreased drastically in those cases. This is very similar to what was observed of GX 1+4 in 1996 when it became similarly faint in X-ray. In fact, the flux at which the cessation of X-ray pulsation first occurred is nearly the same as it was in 1996. We suggest that we have, once again, observed the propeller effect in GX 1+4, a phenomenon that is predicted by theoretical models of accreting X-ray pulsars.Comment: 13 pages, 9 figures (available at http://www.physics.purdue.edu/~cui/ftp/cuifigs.tar.gz). To appear in Ap

Vector magnetic field sensing by single nitrogen vacancy center in diamond

In this Letter, we proposed and experimentally demonstrated a method to detect vector magnetic field with a single nitrogen vacancy (NV) center in diamond. The magnetic field in parallel with the axis of the NV center can be obtained by detecting the electron Zeeman shift, while the Larmor precession of an ancillary nuclear spin close to the NV center can be used to measure the field perpendicular to the axis. Experimentally, both the Zeeman shift and Larmor precession can be measured through the fluorescence from the NV center. By applying additional calibrated magnetic fields, complete information of the vector magnetic field can be achieved with such a method. This vector magnetic field detection method is insensitive to temperature fluctuation and it can be applied to nanoscale magnetic measurement.Comment: 5 pages, 5 figure

Evidence for "Propeller" Effects In X-ray Pulsars GX 1+4 And GROJ1744-28

We present observational evidence for "propeller" effects in two X-ray pulsars, GX 1+4 and GROJ1744-28. Both sources were monitored regularly by the Rossi X-ray Timing Explorer (RXTE) throughout a decaying period in the X-ray brightness. Quite remarkably, strong X-ray pulsation became unmeasurable when total X-ray flux had dropped below a certain threshold. Such a phenomenon is a clear indication of the propeller effects which take place when pulsar magnetosphere grows beyond the co-rotation radius as a result of the decrease in mass accretion rate and centrifugal force prevents accreting matter from reaching the magnetic poles. The entire process should simply reverse as the accretion rate increases. Indeed, steady X-ray pulsation was reestablished as the sources emerged from the non-pulsating faint state. These data allow us to directly derive the surface polar magnetic field strength for both pulsars: 3.1E+13 G for GX 1+4 and 2.4E+11 G for GROJ1744-28. The results are likely to be accurate to within a factor of 2, with the total uncertainty dominated by the uncertainty in estimating the distances to the sources. Possible mechanisms for the persistent emission observed in the faint state are discussed in light of the extreme magnetic properties of the sources.Comment: 12 pages including 3 ps figures. To appear in ApJ Letters Vol. 48

Site Selective Antibody-Oligonucleotide Conjugation via Microbial Transglutaminase.

Nucleic Acid Therapeutics (NATs), including siRNAs and AntiSense Oligonucleotides (ASOs), have great potential to drug the undruggable genome. Targeting siRNAs and ASOs to specific cell types of interest has driven dramatic improvement in efficacy and reduction in toxicity. Indeed, conjugation of tris-GalNAc to siRNAs and ASOs has shown clinical efficacy in targeting diseases driven by liver hepatocytes. However, targeting non-hepatic diseases with oligonucleotide therapeutics has remained problematic for several reasons, including targeting specific cell types and endosomal escape. Monoclonal antibody (mAb) targeting of siRNAs and ASOs has the potential to deliver these drugs to a variety of specific cell and tissue types. However, most conjugation strategies rely on random chemical conjugation through lysine or cysteine residues resulting in conjugate heterogeneity and a distribution of Drug:Antibody Ratios (DAR). To produce homogeneous DAR-2 conjugates with two siRNAs per mAb, we developed a novel two-step conjugation procedure involving microbial transglutaminase (MTGase) tagging of the antibody C-terminus with an azide-functionalized linker peptide that can be subsequently conjugated to dibenzylcyclooctyne (DBCO) bearing oligonucleotides through azide-alkyne cycloaddition. Antibody-siRNA (and ASO) conjugates (ARCs) produced using this strategy are soluble, chemically defined targeted oligonucleotide therapeutics that have the potential to greatly increase the number of targetable cell types

Analytical model of non-Markovian decoherence in donor-based charge quantum bits

We develop an analytical model for describing the dynamics of a donor-based charge quantum bit (qubit). As a result, the quantum decoherence of the qubit is analytically obtained and shown to reveal non-Markovian features: The decoherence rate varies with time and even attains negative values, generating a non-exponential decay of the electronic coherence and a later recoherence. The resulting coherence time is inversely proportional to the temperature, thus leading to low decoherence below a material dependent characteristic temperature.Comment: 19 pages, 3 figure

First-Order Provenance Games

We propose a new model of provenance, based on a game-theoretic approach to query evaluation. First, we study games G in their own right, and ask how to explain that a position x in G is won, lost, or drawn. The resulting notion of game provenance is closely related to winning strategies, and excludes from provenance all "bad moves", i.e., those which unnecessarily allow the opponent to improve the outcome of a play. In this way, the value of a position is determined by its game provenance. We then define provenance games by viewing the evaluation of a first-order query as a game between two players who argue whether a tuple is in the query answer. For RA+ queries, we show that game provenance is equivalent to the most general semiring of provenance polynomials N[X]. Variants of our game yield other known semirings. However, unlike semiring provenance, game provenance also provides a "built-in" way to handle negation and thus to answer why-not questions: In (provenance) games, the reason why x is not won, is the same as why x is lost or drawn (the latter is possible for games with draws). Since first-order provenance games are draw-free, they yield a new provenance model that combines how- and why-not provenance