The efficacy of the semi-blind approach of transversus abdominis plane block on postoperative analgesia in patients undergoing inguinal hernia repair: a prospective randomized double-blind study

A Ebru Salman,1 Fahri Yetisir,2 Banu Yürekli,3 Mustafa Aksoy,1 Murat Yildirim,2 Mehmet Kiliç21Anesthesiology and Reanimation Department, 2General Surgery Department, Atatürk Research and Training Hospital, Ankara, Turkey; 3Endocrinology Department, Bozyaka Research and Training Hospital, Izmir, TurkeyPurpose: In this prospective, randomized, double-blind study, our aim was to compare the analgesic efficacy of the semi-blind approach of transversus abdominis plane (TAP) block with a placebo block in patients undergoing unilateral inguinal hernia repair.Methods: After receiving hospital ethical committee approval and informed patient consents, American Society of Anesthesiologists (ASA) I–III patients aged 18–80 were enrolled in the study. Standard anesthesia monitoring was applied to all patients. After premedication, spinal anesthesia was administered to all patients with 3.5 mL heavy bupivacaine at the L3-L4 subarachnoid space. Patients were randomly allocated into 2 groups. Group I (n = 32) received a placebo block with 20 mL saline, Group II (n = 32) received semi-blind TAP block with 0.25% bupivacaine in 20 mL with a blunt regional anesthesia needle into the neurofascial plane via the lumbar triangle of Petit near the midaxillary line before fascial closure. At the end of the operation, intravenous (IV) dexketoprofen was given to all patients. The verbal analog scale (VAS) was recorded at 2, 4, 6, 12, and 24 hours postoperatively. Paracetamol IV was given to patients if their VAS score > 3. A rescue analgesic of 0.05 mg/kg morphine IV was applied if VAS > 3. Total analgesic consumption and morphine requirement in 24 hours were recorded.Results: TAP block reduced VAS scores at all postoperative time points (P < 0.001). Postoperative analgesic and morphine requirement in 24 hours was significantly lower in group II (P < 0.01).Conclusion: Semi-blind TAP block provided effective analgesia, reducing total 24-hour postoperative analgesic consumption and morphine requirement in patients undergoing elective unilateral inguinal hernia repair.Keywords: pain, inguinal hernia, transversus abdominis plan

Rootstock potential of Turkish Lagenaria siceraria germplasm for watermelon: Plant growth, yield and quality [Türkiye'deki Lagenaria siceraria gen kaynaklarının karpuz için anaçlık potansiyeli: Bitki gelişimi, verim ve kalite]

The rootstock potential of 21 bottle gourds (Lagenaria siceraria) collected from the Mediterranean region (Turkey) was investigated for watermelon with regard to plant growth, yield, and fruit quality. The Crimson Tide watermelon cultivar was used as a scion and 2 commercial rootstocks (L. siceraria) were also used for comparison. In greenhouse conditions, the survival rate of grafted plants and the eff ect of rootstocks on plant growth were determined. The grafted plants were planted under low tunnels in early spring and the eff ects of the rootstocks on early yield, total yield, and fruit quality were evaluated. The survival rates of the grafted plants varied from 83% to 100%. Survival rates of those with commercial rootstocks and local rootstocks were similar. Plants grafted onto 20-02, 31-09, 31-43, 35-01, and 46-03 were more vigorous than ungrafted control plants. Compared to the control plants, grafted plants had 37% to 80% higher plant dry weight. All of the grafted plants except CT/Macis produced a higher yield than the control plants. The plants grafted onto 6 of the local rootstocks had significantly greater total yields than those grafted onto the commercial rootstocks. Among the local bottle gourd landraces tested, the 01-16, 07-45, 20-06, 31-09, 31-15, and 46-03 were found to be promising genotypes with regard to total yield. Early yield was not significantly affected by rootstock. The quality parameters of the fruits harvested from the grafted and control plants were found to be similar except for a limited number of graft combinations. It was concluded that germplasm from Turkish bottle gourds has a high rootstock potential for watermelon with regard to the investigated parameters. © TÜBİTAK

The Importance of Parameters: MPV, MPV/Thrombocyte Ratio and Neutrophil/Lymphocyte Ratio in Sorafenib Treatment Response of Patients with Hepatocellular Cancer

PubMedID: 28691138[No abstract available