5,872 research outputs found
Comportamento das fêmeas de Elasmopalpus lignosellus (Lepidoptera: Pyralidae) associado a liberação de feromônio sexual.
Agrotóxicos em hortaliças: segurança alimentar, riscos socioambientais e políticas públicas para promoção da saúde.
Propriedades calorimétricas da água e vidros citoplasmáticos associados à tolerância a dessecação em sementes de Coffee arabica L.
On the optimal control of a cascade of hydro-electric power stations
In this paper we consider a model for a cascade of hydroelectric
power stations where some of the
stations have reversible turbines. The objective of our work is to optimize the profit of power production
satisfying restrictions on the water level in the reservoirs. The problem is considered in the framework
of discretetime
optimal control and is solved using numerical methods. The optimization uses real data
of market prices of electricity, water levels at the reservoirs, and water flows in different types of days
Qualidade do polvilho durante a fermentação da fécula de mandioca, com e sem adição de inóculos.
A compendium of current developments on polysaccharide and protein-based microneedles
Microneedles (MNs), i.e. minimally invasive three-dimensional microstructures that penetrate the stratum corneum inducing relatively little or no pain, have been studied as appealing therapeutic vehicles for transdermal drug delivery. Over the last years, the fabrication of MNs using biopolymers, such as polysaccharides and proteins, has sparked the imagination of scientists due to their recognized biocompatibility, biodegradability, ease of fabrication and sustainable character. Owing to their wide range of functional groups, polysaccharides and proteins enable the design and preparation of materials with tunable properties and functionalities. Therefore, these biopolymer-based MNs take a revolutionary step offering great potential not only in drug administration, but also in sensing and response to physiological stimuli. In this review, a critical and comprehensive overview of the polysaccharides and proteins employed in the design and engineering of MNs will be given. The strategies adopted for their preparation, their advantages and disadvantages will be also detailed. In addition, the potential and challenges of using these matrices to deliver drugs, vaccines and other molecules will be discussed. Finally, this appraisal ends with a perspective on the possibilities and challenges in research and development of polysaccharide and protein MNs, envisioning the future advances and clinical translation of these platforms as the next generation of drug delivery systems.publishe
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