3,245 research outputs found
Canning study: Impact of new public buying habits
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Nouveaux OrthoptĂšres (Ensifera, Insecta) du Trias des Vosges (France)
Trois nouveaux Orthoptera, Ensifera (Hagloidea et Gryllavoidea) du GrÚs à Voltzia (Buntsandstein supérieur, Trias inférieur/moyen) des Vosges (France) représentés par des ailes antérieures, sont décrits. Galliagryllavus vogesiacus n. gen., n.sp. (Gryllavidae) montre des affinités avec Gryllavus madyge nicus SHAROV 1968 du Trias de Madygen (Kirghizistan). Triassoparacyrtophyllites bifurcatus n. gen., n.sp. (Tuphellidae) présente des analogies avec Pa racyrtophillites undulatus SHAROV 1968 du Jurassique supérieur de Karatau (Kazakhstan). Voltziahagla pseudoveinosa n. gen., n.sp. (Haglidae) semble proche du genre Archaboilus MARTYNOV 1937 du Jurassique inférieur de Shurab (Tadjikistan).
Ces trois Ensifera qui appartiennent à des familles distinctes mettent en évidence la diversité de ce groupe à la limite du Trias inférieur/moyen. Une révision cladistique des Hagloidea et des Gryllavoidea serait nécessaire pour pouvoir déterminer les relations phylogénétiques entre ces différentes familles.Three new Orthoptera, Ensifera (Hagloidea and Gryllavoidea) from the Grés à Voltzia (Upper Buntsandstein, transition Lower / Middle Triassic) of the Vosges (France) are described based on forewings. Galliagryllavus vogesiacus n.gen., n.sp. (Gryllavidae) shows affinities with Gryllavus madygenicus SHAROV 1968 from the Triassic of Madygen (Kirghizistan). Triassoparacyrtophyllites bifurcatus n.gen., n.sp. (Tuphellidae) displays some similarities with Paracyrtophillites undulatus SHAROV 1968 from the Upper Jurassic of Karatau (Kazakhstan). Voltziahagla pseudoveinosa n.gen., n.sp. (Haglidae) seems close to the genus Archaboilus MARTYNOV 1937 from the Lower Jurassic of Shurab (Tadjikistan).
These three Ensifera which belong to distinct families underscore the diversity of the Hagloidea and the Gryllavoidea at the boundary between the Lower and Middle Triassic. A cladistic study would be necessary to determine the phylogenetical relationships between the different families
Nouveaux OrthoptĂšres (Ensifera, Insecta) du Trias des Vosges (France)
Three new Orthoptera, Ensifera (Hagloidea and Gryllavoidea) from the Grés à Voltzia (Upper Buntsandstein, transition Lower / Middle Triassic) of the Vosges (France) are described based on forewings. Galliagryllavus vogesiacus n.gen., n.sp. (Gryllavidae) shows affinities with Gryllavus madygenicus SHAROV 1968 from the Triassic of Madygen (Kirghizistan). Triassoparacyrtophyllites bifurcatus n.gen., n.sp. (Tuphellidae) displays some similarities with Paracyrtophillites undulatus SHAROV 1968 from the Upper Jurassic of Karatau (Kazakhstan). Voltziahagla pseudoveinosa n.gen., n.sp. (Haglidae) seems close to the genus Archaboilus MARTYNOV 1937 from the Lower Jurassic of Shurab (Tadjikistan). These three Ensifera which belong to distinct families underscore the diversity of the Hagloidea and the Gryllavoidea at the boundary between the Lower and Middle Triassic. A cladistic study would be necessary to determine the phylogenetical relationships between the different families
On the use of blow up to study regularizations of singularities of piecewise smooth dynamical systems in
In this paper we use the blow up method of Dumortier and Roussarie
\cite{dumortier_1991,dumortier_1993,dumortier_1996}, in the formulation due to
Krupa and Szmolyan \cite{krupa_extending_2001}, to study the regularization of
singularities of piecewise smooth dynamical systems
\cite{filippov1988differential} in . Using the regularization
method of Sotomayor and Teixeira \cite{Sotomayor96}, first we demonstrate the
power of our approach by considering the case of a fold line. We quickly
recover a main result of Bonet and Seara \cite{reves_regularization_2014} in a
simple manner. Then, for the two-fold singularity, we show that the regularized
system only fully retains the features of the singular canards in the piecewise
smooth system in the cases when the sliding region does not include a full
sector of singular canards. In particular, we show that every locally unique
primary singular canard persists the regularizing perturbation. For the case of
a sector of primary singular canards, we show that the regularized system
contains a canard, provided a certain non-resonance condition holds. Finally,
we provide numerical evidence for the existence of secondary canards near
resonance.Comment: To appear in SIAM Journal of Applied Dynamical System
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Levothyroxine effects on depressive symptoms and limbic glucose metabolism in bipolar disorder: a randomized, placebo-controlled positron emission tomography study.
Adding supraphysiologic doses of levothyroxine (L-T4) to standard treatment for bipolar depression shows promise, but the mechanisms underlying clinical improvement are unknown. In a previous pilot study, L-T4 treatment reduced depression scores and activity within the anterior limbic network. Here we extended this work in a randomized, double-blind, placebo-controlled study of patients with bipolar depression. Cerebral glucose metabolism was assessed with positron emission tomography and [F-18]fluorodeoxyglucose before and after 6 weeks of treatment with L-T4 (n=15) or placebo (n=10) in 12 volumes of interest (VOIs): the bilateral thalamus, amygdala, hippocampus, dorsal striatum and ventral striatum, and midline cerebellar vermis and subgenual cingulate cortex. Radioactivity in the VOIs, normalized to whole-brain radioactivity was taken as a surrogate index of glucose metabolism, and markers of thyroid function were assayed. Changes in brain activity and their association with clinical response were assessed using statistical parametric mapping. Adjunctive L-T4 treatment produced a significant decline in depression scores during the 6-week treatment. In patients treated with L-T4, we found a significant decrease in regional activity at P<0.05 after Bonferroni correction in the left thalamus, right amygdala, right hippocampus, left ventral striatum and the right dorsal striatum. Decreases in the left thalamus, left dorsal striatum and the subgenual cingulate were correlated with a reduction in depression scores (P<0.05 after Bonferroni correction). Placebo treatment was associated with a significant decrease in activity only in the right amygdala, and no region had a change in activity that was correlated with change in depression scores. The groups differed significantly in the relationship between the changes in depression scores and in activity in the thalamus bilaterally and the left ventral striatum. The findings provide evidence that administration of supraphysiologic thyroid hormone improves depressive symptoms in patients with bipolar disorder by modulating function in components of the anterior limbic network
Reduced basis surrogates for quantum spin systems based on tensor networks
Within the reduced basis methods approach, an effective low-dimensional
subspace of a quantum many-body Hilbert space is constructed in order to
investigate, e.g., the ground-state phase diagram. The basis of this subspace
is built from solutions of snapshots, i.e., ground states corresponding to
particular and well-chosen parameter values. Here, we show how a greedy
strategy to assemble the reduced basis and thus to select the parameter points
can be implemented based on matrix-product-states (MPS) calculations. Once the
reduced basis has been obtained, observables required for the computation of
phase diagrams can be computed with a computational complexity independent of
the underlying Hilbert space for any parameter value. We illustrate the
efficiency and accuracy of this approach for different one-dimensional quantum
spin-1 models, including anisotropic as well as biquadratic exchange
interactions, leading to rich quantum phase diagrams.Comment: 15 pages, 13 figure
Expression, Processing, and Localization of PmpD of Chlamydia trachomatis Serovar L2 during the Chlamydial Developmental Cycle
BACKGROUND: While families of polymorphic membrane protein (pmp) genes have been identified in several Chlamydia species, their function remains mostly unknown. These proteins are of great interest, however, because of their location in the outer membrane and possible role in chlamydial virulence. METHODOLOGY/PRINCIPAL FINDING: We analyzed the relative transcription of the pmpD gene, a member of the pmp gene family in C. trachomatis serovar L2, and its protein product translation and processing during the chlamydial developmental cycle. By real-time reverse transcription polymerase chain reaction, the pmpD gene was found to be upregulated at 16 to 24 four hours after infection. Using polyclonal antibodies generated against the predicted passenger domain of PmpD, we demonstrated that it is initially localized on the surface of reticulate bodies, followed by its secretion outside Chlamydia starting at 24 hours after infection. In elementary bodies, we found a approximately 157 kDa PmpD only inside the cell. Both events, the upregulation of pmpD gene transcription and PmpD protein processing and secretion, are coincidental with the period of replication and differentiation of RBs into EBs. We also demonstrated that, in the presence of penicillin, the cleavage and secretion of the putative passenger domain was suppressed. CONCLUSION/SIGNIFICANCE: Our results are in agreement with the general concept that PmpD is an autotransporter protein which is post-translationally processed and secreted in the form of the putative passenger domain outside Chlamydia at mid- to- late point after infection, coinciding with the development of RBs into EBs
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